Name: FDGlcU
Brand: TargetMol
SKU: T86414
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

待询

3-6月

50 mg

待询

3-6月

100 mg

待询

3-6月

生物活性

产品描述	FDGlcU is a fluorescent probe used for non-invasive imaging, demonstrating high fluorescent activity. When conjugated with two mono-glucuronides, it is non-fluorescent (Ex/Em=480/514 nm) [1].
体外活性	FDGlcU, at a concentration of 0.5 μg/mL over 12 hours, demonstrates enzymatic activity and inhibits βG activity in live bacteria [1].
体内活性	FDGlcU (7.3 μM/kg) is used for in vivo time-lapse imaging of bacterial βG activity [1]. For whole-body imaging of intestinal βG activity [1], administer 50 μL of DDW, FDGlcU (7.3 μM/kg), and fluorescein (7.3 μM/kg) via gavage on the day of imaging. Anesthetize the mice with isoflurane and perform whole-body optical imaging using an IVIS spectrum optical imaging system with a GFP filter set. In a biodistribution study, sacrifice the mice 3 hours after gavage with FDGlcU or fluorescein (λex = 480 nm, λem = 514 nm). This protocol should be modified according to specific needs.

化学信息

分子量	893.63
分子式	C₃₉H₂₈F₅NO₁₈
CAS No.	209540-67-0
Smiles	O=C1OC2(C=3C1=CC(NC(=O)C4=C(F)C(F)=C(F)C(F)=C4F)=CC3)C=5C(OC=6C2=CC=C(O[C@@H]7O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]7O)C6)=CC(O[C@@H]8O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]8O)=CC5

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.

FDGlcU