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Anti-ZSWIM3 Polyclonal Antibody

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货号 TMAB-14464

Anti-ZSWIM3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZSWIM3。Anti-ZSWIM3 Polyclonal Antibody 可用于 WB。

Anti-ZSWIM3 Polyclonal Antibody

Anti-ZSWIM3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14464

Anti-ZSWIM3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZSWIM3。Anti-ZSWIM3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-ZSWIM3 Polyclonal Antibody is a Rabbit antibody targeting ZSWIM3. Anti-ZSWIM3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZSWIM3 (Zinc finger SWIM domain-containing protein 3) is a 696 amino acid protein that contains one SWIM-type zinc finger. SWIM domains are found in a variety of eukaryotic and prokaryotic proteins and are thought to be critical for certain ubiquitination reactions. The gene encoding ZSWIM3 maps to human chromosome 20, which contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ZSWIM3
抗原种属
Human
基因名称
ZSWIM3
基因ID
蛋白名称
Zinc finger SWIM domain-containing protein 3
Uniprot ID
功能
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
化学信息
分子量Theoretical: 79 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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