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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PIK3R1 Polyclonal Antibody 2

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货号 TMAB-11446

Anti-PIK3R1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PIK3R1。Anti-PIK3R1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-PIK3R1 Polyclonal Antibody 2

Anti-PIK3R1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-11446

Anti-PIK3R1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PIK3R1。Anti-PIK3R1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-PIK3R1 Polyclonal Antibody 2 is a Rabbit antibody targeting PIK3R1. Anti-PIK3R1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Horse,Rabbit,Sheep,Goat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic.
组织特异性Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PI3K p85
抗原种属
Human
基因名称
PIK3R1
基因ID
5295
蛋白名称
Phosphatidylinositol 3-kinase regulatory subunit alpha
Uniprot ID
P27986
功能
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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