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Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2

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产品编号 TMAB-11387

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-TPH2 (Ser19)。Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2

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Rating icon 还可以
产品编号 TMAB-11387

Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-TPH2 (Ser19)。Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-TPH2 (Ser19). Anti-Phospho-TPH2 (Ser19) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Rat (predicted:Human,Dog,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Brain specific.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH) and tryptophan hydroxylase 2 (TPH2) comprise a small family of monooxygenases that catalyze the rate-limiting step in the catabolism of aromatic L-amino acids and utilize tetrahydropterine as a cofactor. TPH2 is highly expressed in the central nervous system (CNS), mainly in the brain. TPH2 catalyzes the first step in the biosynthesis of serotonin in the CNS and melatonin in the pineal gland, and may be involved in the pathology of several neuropsychiatric disorders. Glucocorticoid-mediated reduction of TPH2 is associated with the etiology of mood disorders, specifically psychotic major depression, and TPH2 may be related to dysregulation of serotonin neurotransmission in the brain which commonly leads to suicidal behavior.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human TPH2 around the phosphorylation site of Ser19
抗原种属
Human
基因名称
TPH2
基因ID
121278
蛋白名称
Tryptophan 5-hydroxylase 2
Uniprot ID
Q8IWU9
化学信息
分子量Theoretical: 56 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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