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Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2
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还可以产品编号 TMAB-11378
Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Tie2 (Ser1119)。Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2
Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-11378
Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Tie2 (Ser1119)。Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Tie2 (Ser1119). Anti-Phospho-Tie2 (Ser1119) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Cell junction. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Secreted. Note=Recruited to cell-cell contacts in quiescent endothelial cells. Colocalizes with the actin cytoskeleton and at actin stress fibers during cell spreading. Recruited to the lower surface of migrating cells, especially the rear end of the cell. Proteolytic processing gives rise to a soluble extracellular domain that is secreted. |
| 组织特异性 | Predominantly expressed in endothelial cells and their progenitors, the angioblasts. Has been directly found in placenta and lung, with a lower level in umbilical vein endothelial cells, brain and kidney. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human Tie2 around the phosphorylation site of Ser1119 |
| 抗原种属 | Human |
| 基因名称 | TEK |
| 基因ID | |
| 蛋白名称 | Angiopoietin-1 receptor |
| Uniprot ID | |
| 功能 | This protein is a protein tyrosine-kinase transmembrane receptor for angiopoietin 1. It may constitute the earliest mammalian endothelial cell lineage marker. Probably regulates endothelial cell proliferation, differentiation and guides the proper patterning of endothelial cells during blood vessel formation. |
| 分子量 | Theoretical: 124 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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