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Anti-ERG/KCNH2 Polyclonal Antibody

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货号 TMAB-05666

Anti-ERG/KCNH2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ERG/KCNH2。Anti-ERG/KCNH2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ERG/KCNH2 Polyclonal Antibody

Anti-ERG/KCNH2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05666

Anti-ERG/KCNH2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ERG/KCNH2。Anti-ERG/KCNH2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-ERG/KCNH2 Polyclonal Antibody is a Rabbit antibody targeting ERG/KCNH2. Anti-ERG/KCNH2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Highly expressed in heart and brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ERG/KCNH2
抗原种属
Human
基因名称
KCNH2
基因ID
蛋白名称
Potassium voltage-gated channel subfamily H member 2
Uniprot ID
功能
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
化学信息
分子量Theoretical: 127 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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