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Anti-DYX1C1 Polyclonal Antibody

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货号 TMAB-05375

Anti-DYX1C1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DYX1C1。Anti-DYX1C1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-DYX1C1 Polyclonal Antibody

Anti-DYX1C1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05375

Anti-DYX1C1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DYX1C1。Anti-DYX1C1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-DYX1C1 Polyclonal Antibody is a Rabbit antibody targeting DYX1C1. Anti-DYX1C1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Zebrafish)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm.
组织特异性Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DYX1C1
抗原种属
Human
基因名称
DNAAF4
基因ID
蛋白名称
Dynein assembly factor 4, axonemal
Uniprot ID
功能
Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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