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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-C16orf57 Polyclonal Antibody

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货号 TMAB-03305

Anti-C16orf57 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C16orf57。Anti-C16orf57 Polyclonal Antibody 可用于 WB。

Anti-C16orf57 Polyclonal Antibody

Anti-C16orf57 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03305

Anti-C16orf57 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C16orf57。Anti-C16orf57 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-C16orf57 Polyclonal Antibody is a Rabbit antibody targeting C16orf57. Anti-C16orf57 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Involvement in disease;Defects in C16orf57 are the cause of poikiloderma with neutropenia (PN). PN is a genodermatosis characterized by poikiloderma, pachyonychia and chronic neutropenia. The disorder starts as a papular erythematous rash on the limbs during the first year of life. It gradually spreads centripetally and, as the papular rash resolves, hypo- and hyperpigmentation result, with development of telangiectasias. Another skin manifestation is pachyonychia, but alopecia and leukoplakia are distinctively absent. One of the most important extracutaneous symptoms is an increased susceptibility to infections, mainly affecting the respiratory system, primarily due to a chronic neutropenia and to neutrophil functional defects. Bone marrow abnormalities account for neutropenia and may evolve into myelodysplasia associated with the risk of leukemic transformation. Poikiloderma with neutropenia shows phenotypic overlap with Rothmund-Thomson syndrome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human C16orf57
抗原种属
Human
基因名称
USB1
基因ID
79650
蛋白名称
U6 snRNA phosphodiesterase
Uniprot ID
Q9BQ65
功能
Putative phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as a ribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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