Anti-ARTS1 Antibody (2L658) is a Rabbit antibody targeting ARTS1. Anti-ARTS1 Antibody (2L658) can be used in WB,IHC-P,IHC-Fr,IF.

IgG

2L658

Human,Mouse,Rat

WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200

Monoclonal

A synthesized peptide: human ERAP1

Human

ERAP1

Endoplasmic reticulum aminopeptidase 1

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.