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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ADAM32 Polyclonal Antibody

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货号 TMAB-02293

Anti-ADAM32 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADAM32。Anti-ADAM32 Polyclonal Antibody 可用于 WB。

Anti-ADAM32 Polyclonal Antibody

Anti-ADAM32 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02293

Anti-ADAM32 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADAM32。Anti-ADAM32 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAM32 Polyclonal Antibody is a Rabbit antibody targeting ADAM32. Anti-ADAM32 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Horse,GuineaPig)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein (Potential).
组织特异性Testis specific.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ADAM32 was first discovered in a search for testis-specific proteinases. ADAM32 was identified in human, rat, mouse, macaque and chimp, and thus far has been found only in testis. In mice, ADAM32 is found on the sperm surface, where it may play a role in fertilization. ADAM32 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full length ADAM32 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a short spacer region, then the transmembrane domain and a cytoplasmic domain. Like many of the reproductive-specific ADAMS, ADAM32 plays a non-enzymatic role, or (as is the case for ADAMs 1 & 2 (fertilin alpha and beta)), the protein acts in concert with a proteolytically active ADAM to process proteins. Little is known about interactions between ADAM32 and other ADAMs. Several different sequences for human ADAM32 are published; 787, 688, 649, 629, and 279 amino acids in length. The 688 amino acid form is identical to the 787 AA form until the EGF-like domain, and lacks the TM and cytoplasmic domains. The 649 AA form is likewise identical to the longer form, just to the start of the TM domain, and also lacks the TM and cytoplasmic domains. The 629 AA form has a deletion of 107 residues midway into the MP-like domain, and lacks the amino end of the disintegrin domain, but contains the rest of the domains found in the full-length ADAM32. The predicted masses for the different versions are 87.8, 76.9, 72.9, 70.9 and 32.1, respectively, for the 786, 688, 649, 629 and 279 AA forms.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAM32
抗原种属
Human
基因名称
ADAM32
基因ID
203102
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 32
Uniprot ID
Q8TC27
功能
May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein (By similarity)
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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