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  • SLP7111228
    SLP-7111228,SLP 7111228
    T346581449765-82-5
    SLP7111228 is an effective and selective SphK1 inhibitor (Ki = 48 nM).
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  • SLP7111228 hydrochloride
    T852801449768-48-2
    SLP7111228 is a potent, selective SPHK1 inhibitor with Ki values of 0.048 μM for SPHK1 and >10 μM for SPH2K, showing a concentration-dependent reduction of sphingosine-1-phosphate (S1P) in U937 cells without affecting sphingosine levels. In vivo, it dose-dependently lowers S1P blood levels in rats.
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