neolitsine

Neolitsine has anthelmintic activity, it exhibits EC90 values (concentration at which 90% loss of larval motility is observed) of 6.4 microg/mL.Neolitsine and dicentrine have potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM.

Seconeolitsine，一种抗生素，是一种靶向拓扑异构酶 I(TopA)的抑制剂。Seconeolitsine 也是一种新的抗菌剂，可以抑制 S. pneumoniae 的生长。Seconeolitsine 具有抑制 TopA 的活性，其 b>IC50值为 17 μM。Seconeolitsine 可用于对其他抗生素耐药的肺炎链球菌感染的研究。