angiotensin

Angiotensin (1-7) acetate (Ang-(1-7) acetate) 是存在于血管紧张素中的一段氨基酸序列，具有抗纤维化和心脏保护作用，抑制纯化的犬血管紧张素转换酶 (ACE) 活性。Angiotensin (1-7) acetate 抑制肿瘤细胞的生长并减少几种类型癌症的局部炎症和血管生成，阻断血管紧张素 Ⅱ 诱导的平滑肌细胞增殖和肥大，可用于研究动脉粥样硬化和新型冠状病毒感染。

Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性，因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮，是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大，并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。

Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.

Firibastat (RB150) 是一种具有口服活性的 EC33 前体药物。Firibastat 是一种首创的脑氨基肽酶 A(APA) 抑制剂 (Ki=200 nM)，选择性地抑制高血压大鼠脑血管紧张素 II 转化为血管紧张素 III，降低血压。

Trichlormethiazide (Naqua) 是一种口服具有活力的噻嗪类利尿剂，具有降压作用。它能够提高急性肾功能衰竭大鼠的尿量、Na 和 K 排泄，并有改善降低的肌酐清除率。

Sacubitril/Valsartan (LCZ696)，以1:1摩尔比由Valsartan（一种ARB）和Sacubitril（AHU377）组成，为创新口服血管紧张素受体-脑啡肽酶（ARN）双重抑制剂，旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡，有助于改善糖尿病心肌病。

Icatibant acetate 是一种特异性缓激肽 B2 受体拮抗剂，其 IC50=1.07 nM，Ki=0.798 nM。

Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂，具有抗高血压活性。

Saralasin acetate(34273-10-4 free base) 是一种非选择性血管紧张素 II 拮抗剂。

Angiotensin 1/2 + A (2 - 8) Acetate 是一种血管收缩剂。

Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor.

Angiotensin III TFA is an agonist of angiotensin 1 (AT1) and AT2 receptor.

Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.

Angiotensin I-13C6,15N (human, mouse, rat) TFA 是经过13C 和15N 标记的蛋白质,具体为Angiotensin I (human, mouse, rat) TFA 的同位素标记形式。此化合物作为angiotensin II的前体，在血管紧张素转化酶 (ACE) 的作用下被裂解, 产生angiotensin II。

Angiotensin I/II (1-7) amide is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. Angiotensin I/II amide is an amide derivative of angiotensin II that is a powerful vasoco

Angiotensin I/II (2-7) is a peptide that contains the amino acids 2-7 and is converted from Angiotensin I/II peptide. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. Angiotensin also stimulates th

Angiotensin 1/2 (5-7) is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays a

Angiotensin 1/2 (5-7) acetate 是一种具有 H2N-Ile-His-Pro-OH 序列的肽。血管紧张素是一种寡肽，是一种激素和一种强大的双肽原。它来源于前体分子血管紧张素原，一种在肝脏中产生的血清球蛋白。它在肾素-血管紧张素系统中起重要作用。

Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and electrolyte, as well as homeostasis

The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.

(Sar¹)-Angiotensin II acetate 是血管紧张素 II 的类似物，是血管紧张素 AT1 受体的特异性激动剂。它与富含脑膜的颗粒结合，Kd 为 2.7 nM。它可以刺激胚胎鸡肌细胞中的蛋白质合成和细胞生长。

Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angiotensin I is then hydrolyzed by angiotensin-converting enzyme (ACE) to produce biologically active Angiotensin II. Angiotensin II has been extensively studied for its potential applications in the treatment of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.

Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。