amf

PBE-AMF是一种具有抗癌活性的前药,能够活化H2O2.它通过抑制DNA合成、降低ATP水平、诱导细胞凋亡(apoptosis)及阻碍细胞周期来抑制肿瘤细胞增殖.此化合物在抑制MDA-MB-231细胞增殖方面表现出高效性和选择性(IC50=6.4 μM),同时对非癌性MCF-10A细胞具有较低的毒性影响.

PBA-AMF 在H2O2的激活下,能释放氨甲酰(AMF),并具有高选择性地抑制乳腺癌细胞增殖的功能,对非癌细胞则无影响.它通过多种机制达到抑制肿瘤增殖的效果,包括抑制DNA合成、降低ATP水平、诱导细胞凋亡(Apoptosis)及阻止细胞周期的进行.PBA-AMF亦可用于针对与H2O2水平升高相关的肿瘤与其他疾病的研究.

M-COPA is a golgi disruptor which inhibits cell surface expression of MET protein and the ADP-ribosylation factor 1 (Arf1) activation. M-COPA also inhibits angiogenesis through suppression of both VEGFR1 2 and nuclear factor-kappaB (NF-kappaB) signaling pathways.

Amfenac Sodium Hydrate 是一种含有乙酸部分的非甾体镇痛抗炎药，是 COX-2抑制剂。

amflutizole 用于治疗痛风，是一种黄嘌呤氧化酶抑制剂。

Azidamfenicol 抑制核糖体肽基转移酶，Ki 为 22 µM。Azidamfenicol 是一种广谱氯霉素类抗生素。

Oxamflatin (Metacept-3) 一种是选择性的组蛋白去乙酰化酶（HDAC）抑制剂，具有高效（IC50＝15.7 nM）和点击化学合成的特点，其炔基能够与含有叠氮基团的分子进行铜催化的叠氮-炔烃环加成反应（CuAAc）。

Amfenac promotes apoptosis in ARPE-19 cell culture.

Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.

Amfepentorex fumarate 曾作为一种食欲抑制剂被推向市场。

Amfepentorex 在1970年代于法国作为一种食欲抑制剂被推向市场。

Brolamfetamine, 也称为Dimethoxybromoamphetamine (DOB) 和bromo-DMA，是一种苯乙胺类化合物中的取代型苯丙胺和迷幻化合物。

Amfonelic Acid is a dopamine uptake blocker.

Isamfazone is utilized in the chemical and pharmacological studies on substituted pyridazones, the discovery of novel anti-inflammatory agents by aligning screening.

BAMF is a chemical reagent used in the chemical modification of proteins, mainly in the acetylation process.

Metamfazone is a biochemical.

Cipamfylline is a xanthine, a theophylline analogue, and is a potent and selective inhibitor of phosphodiesterase type 4 (PDE-4). Cipamfylline was tested in patients with a diagnosis of atopic dermatitis and in two human models of acute and chronic irritant contact dermatitis. The outcome of the study revealed that cipamfylline was more effective than vehicle in treating atopic dermatitis, but less effective than a group II steroid, hydrocortisone-17-butyrate both in the treatment of atopic dermatitis and irritant contact dermatitis. The absorption of cipamfylline and the subsequent systemic exposure might be the reason why further clinical studies with higher doses of cipamfylline have not been published.

GaMF1.39 是一种针对 F-ATP 合成酶亚基 γ 的抗菌化合物，与 ETC 抑制剂合用时具有增强的抗结核活性。

Diamfenetide is used in sheep and cattle for the treatment of liver fluxobacteria infections.

Avibactam (NXL-104) free acid is a covalent and reversible inhibitor of non-β-lactam β-lactamase (IC50s: 8 nM and 5 nM for β-lactamase TEM-1 and CTX-M-15).

Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodilating and diuretic natriuretic effe

Elotuzumab(HuLuc 63) (anti-SLAMF7) 是一种靶向 SLAMF7 受体的单克隆抗体。Elotuzumab (anti-SLAMF7) 是一种直接激活NK细胞并诱导抗体依赖性细胞毒性的化合物，可联合来那度胺和地塞米松 （Ld） 用于治疗多发性骨髓瘤。

Aristolactam FI shows platelet aggregation inhibitory activity.It is a potential cancer chemotherapeutic and chemopreventive agent.

Canada Balsam filtered 可作为生命科学研究中的生物材料或有机化合物使用。