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Targets Recommended: Potassium Channel

50

抑制剂 & 化合物

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化合物库

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Cat. No. Product Name
L7700 神经再生化合物库

524 compounds
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L8710 铜死亡化合物库

400 compounds
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究
L9210 儿童药物库

972 compounds
972 种儿童药物的独特集合,可用于高通量筛选和高内涵筛选

化合物库

神经再生化合物库
Cat.No: L7700
Compounds: 524
铜死亡化合物库
Cat.No: L8710
Compounds: 400
儿童药物库
Cat.No: L9210
Compounds: 972
Cat. No. Product Name Target Signaling Pathways
T16420 P-1075

Potassium Channel Membrane transporter/Ion channel
P-1075 是磺酰脲受体2相关的 ATP 敏感性的钾通道(SUR2-KIR6)的激活剂,EC50为 45 nM。它在兔子中通过打开线粒体 K (ATP) 通道产生活性氧,产生保护心脏的功效。
T16288 Neuropathiazol

Others Others
Neuropathiazol 引起成年海马神经祖细胞的神经元分化。
T7070 Nomifensine maleate

Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat

Dopamine Receptor GPCR/G Protein; Neuroscience
Nomifensine maleate (Nomifensine (maleate)) 是一种多巴胺摄取的选择性抑制剂,可用于成人注意力缺陷障碍的研究。
T31149 CYM5181

CYM 5181,CYM-5181

CYM5181与机体免疫系统相关,可用来研究多发性硬化、移植排斥反应和成人呼吸窘迫综合征。
T60201 CX717

GluR Neuroscience
CX 717 是 AMPA 受体的正变构调节剂,具有抗抑郁样作用。CX 717 可用于成人注意力缺陷多动障碍(ADHD)的研究。
T4431 Olodanrigan

PD-126055,EMA401

RAAS Endocrinology/Hormones
Olodanrigan (EMA401) 是具有口服活性、高选择性及外周受限的血管紧张素 Ⅱ 类型 2 受体(AT2R)拮抗剂。它的缓解疼痛的机制可能是:抑制增强的 AngII/AT2R 诱导的 p38 和 p42/p44 MAPK 激活,进而阻碍 DRG 神经元的过度兴奋性及 DRG 神经元的萌发。它可用于研究神经性疼痛。
T2669 Berzosertib

VX-970,VE-822

ATM/ATR DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Berzosertib (VE-822) 已用于研究卵巢肿瘤、卵巢浆液性肿瘤、成人实体瘤、晚期实体瘤和晚期实体瘤等治疗的试验。
T24695 Quinabactin

LC-66C6,ABA mimics 1,AM1,LC66C6,LC 66C6

Others Others
Quinabactin (LC-66C6) 是一种有效的磺酰胺脱落酸 ABA 激动剂。Quinabactin 促进成年拟南芥和大豆植物的保卫细胞关闭、抑制水分流失,抑制种子萌发,提高耐旱性。
T37072 Nitroxynil

4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix

Parasite Microbiology/Virology
Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) 为一种广泛用于研究 Fasciola hepatica 感染的驱虫剂,有效作用于寄生虫的成熟及未成熟阶段。
T22821 GSK J5

GSK-J5,GSKJ5

Histone Demethylase Chromatin/Epigenetic
GSK J5 对血吸虫和蠕虫具有抑制作用,常被当作一种吸血虫杀虫剂。GSK J5 以剂量和时间依赖的方式促进血吸虫死亡。GSK J5 可提高血吸虫死亡率、减低成虫活力。
T9566 PY-60

Annexin A; YAP GPCR/G Protein; Stem Cells
PY-60 有效激活针对膜联蛋白 A2 (Kd = 1.4 µM) 的 YAP 转录活性。 PY-60 在能够通过增殖重塑表皮的成年动物中激活促增殖、依赖于 YAP 的转录程序。
T68151L Tallimustine HCl

Tallimustine HCl(115308-98-0 Free base)

DNA DNA Damage/DNA Repair
Tallimustine HCl 是一种DNA 抑制剂,是二霉素的AT 特异性烷化抗肿瘤衍生物。Tallimustine HCl 可用于成人骨髓性白血病的严重联合免疫缺陷小鼠模型,可用于治疗白血病。
T5095 Oxazolone

4-乙氧基亚甲基-2-苯基-2-唑啉-5-酮,4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

Others Others
Oxazolone 已被用作半抗原化剂,可在成年斑马鱼肠道组织中诱导炎症反应,并可用作两种形式的炎症性肠病(如克罗恩病和溃疡性结肠炎)的基因表达研究模型。
T76782 Mogamulizumab

KW-0761

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
Mogamulizumab (KW-0761) 是一种针对 T 细胞 CC 趋化因子受体 4 的 单克隆抗体。Mogamulizumab 具有抗癌活性,通过抗体依赖性细胞毒性 (ADCC) 消除肿瘤细胞,可用于研究癌症、成人T细胞白血病/淋巴瘤 (ATLL)、皮肤T细胞淋巴瘤(CTCL)。
T4341 Betrixaban

贝曲西班,PRT054021

Factor Xa Metabolism
Betrixaban (PRT054021) 是一种口服具有活力的选择性factor Xa(fXa) 抑制剂,IC50=1.5 nM。
T13664 DSP-4 hydrochloride

Neurotoxin DSP 4 (hydrochloride)

Others Others
DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) 是一种高选择性的神经毒素,主要是来自蓝斑 (LC) 的神经元,容易通过血脑屏障。它对成年和发育中大鼠去甲肾上腺素能神经元具有神经毒性作用,可用于中枢和外周去甲肾上腺素能神经元的暂时选择性降解。
T38287 C3a Receptor Agonist

C3a receptor agonist 1,C3a受体激动剂,Complement 3a Receptor Agonist

Complement System Immunology/Inflammation
C3a Receptor Agonist (C3a receptor agonist 1) 结合免疫系统补体途径中的G 蛋白偶联C3a 受体(C3aRs)。在肠缺血再灌注损伤模型中,C3aR 的激活可防止中性粒细胞动员。C3aRs 在成年小鼠的神经祖细胞和未成熟神经元上表达。C3a 在体外刺激神经祖细胞的分化。
T71703L Isomer-Turosteride

Isomer-Turosteride(Isomer-137099-09-3)

Reductase Endocrinology/Hormones; Metabolism
Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) 是一种新型 5α- 还原酶抑制剂。Isomer-Turosteride 在成年大鼠中的抗前列腺作用与抑制T向 DHT 的转化有关。Isomer-Turosteride引起前列腺 DHT 的降低,与 T 含量的继发性增加无关。Isomer-Turosteride 具有抗癌活性,可抑制肿瘤细胞的生长。
T4980 Betrixaban maleate

Factor Xa Metabolism
Betrixaban maleate 是一种非维生素 K 口服抗凝剂,其作用是由 Xa 因子的竞争性和可逆抑制作用驱动的。
T60554 Schnurri-3 inhibitor-1

Others Others
Schnurri-3 inhibitor-1 是有效的 schnurri-3 抑制剂,schnurri-3是成人骨形成的重要调节因子。在成骨细胞系 Shn3FFL 中,Schnurri-3 inhibitor-1 通过 EF1alpha 启动子抑制 Shn3 蛋白表达 (AC50= 2.09 μM)。Schnurri-3 inhibitor-1 可用于骨质疏松症相关的研究。
T38272 Thiacloprid

AChR; Parasite Microbiology/Virology; Neuroscience
Thiacloprid 属于氯烟碱类杀虫剂,主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性,通过疏水或氢相互作用,结合到小沟槽中,改变 DNA 的结构和稳定性。
T32908 l-trans-Phenothrin

l-trans-Phenothrin, as a synthetic pyrethroid, can kill adult fleas and ticks.
T1200 Phenothrin

苯醚菊酯,Sumithrin

Parasite Microbiology/Virology
Phenothrin (Sumithrin) 是一种合成拟除虫菊酯, 可杀死成虫、蜱和人类的头虱。
T70647 CD2019

CD2019 is a retinoic acid receptor beta (rarbeta) agonist, overcoming inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord.
T20960 Luxabendazole

HOE 216V

Luxabendazole is a benzimidazole carbamate broad-spectrum anthelmintic agent. It has proved to be effective against immature and adult stages of the major gastrointestinal nematodes, cestodes, and trematodes.
T29809 AL-1

AL 1,AL1

AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variety of adult tissues of BRAIN; HEART;
T20906 MGK-264

NSC 36678,NSC 406879,ENT 8184

MGK-264, a dicarboxamide synergist, is used to enhance the effects of pesticides. when used in combination with sublethal doses of a variety of plant-derived molluscicides, it also decreases the fecundity of adult L. acuminata and reduces survival of the
T37798 Petromyzonol

Petromyzonol is a tetrahydroxy stearol which serves as the primary spawning pheromone in adult sea lamprey. It is produced in the bile of sea lamprey larvae from the bile acid precursor allocholic acid. While the adult sea lamprey is relatively insensitive to petromyzonol itself, the C-24 sulfate ester (petromyzonol sulfate) is a pheromone and a spawning chemoattractant which can be detected at very low concentrations by lamprey olfactory chemoreceptors. Petromyzonol, petromyzonol sulfate, and a...
T61549 HDAC8-IN-2

HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and greatly reduces egg laying in adult worm pairs [1].
T76938 Camoteskimab

Camoteskimab (AVTX-007)为全人源、高亲和力抗IL-18单克隆抗体,展现于自身炎症性疾病研究潜力,包括成人斯蒂尔病(AOSD)。
T36920 16α-hydroxy Dehydroepiandrosterone

16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2 1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydro...
T35873 C19 Ceramide (d18:1/19:0)

C19 Ceramide (d18:1/19:0)

C19 Ceramide is a naturally occurring ceramide that has been found in J. juncea extracts as well as rat brain and mouse heart.[1],[2],[3] It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 and 37%, respectively, following chronic ethanol exposure.[2] C19 Ceramide is also increased in mouse hearts following administration of angiotensin II.[3]
T68276 Macimorelin acetate

EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate

Macimorelin (EP-1572) acetate,一种 GH 促分泌素,是一种具有口服活性的GHSR 激动剂。Macimorelin acetate 可刺激 GH 的释放。Macimorelin acetate 可用于成人生长激素缺乏症 (AGHD) 和癌症厌食-恶病质综合征 (CACS) 的研究。
T35487 Anacardic Acid Diene

Anacardic acid diene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid. It has antibacterial activity against methicillin resistant S. aureus (MRSA) and S. mutans (MICs = 12.5 and 6.25 μg/ml, respectively). Anacardic acid diene has schistosomicidal activity against adult S. mansoni worms when used at a concentration of 100 μM. It also inhibits soybean lipoxygenase-1 in a time-dependent manner.
T79378 IIIM-8

Melanocortin Receptor GPCR/G Protein; Neuroscience
IIIM-8作为一种黑色素生成抑制剂,在体外和体内均表现出显著地抑制色素生成的功效,同时对成人表皮黑色素细胞(HAEM)不表现出细胞毒性。IIIM-8适用于色素沉着症研究。
T80486 αA-Conotoxin PIVA

αA-Conotoxin PIVA是选择性针对小鼠肌肉nAChR的抑制剂,对成年和胎儿型小鼠肌肉nAChR的IC50分别为2.3 nM及22 nM。该化合物可应用于神经系统疾病研究领域。
T79621 TZ4M

TZ4M 是一种含 2,4-噻唑烷二酮 (TZD) 的抗阿尔茨海默病试剂,可提供神经保护。在人类血浆中,TZ4M 可抑制 AChE。此外,TZ4M 能在东莨菪碱诱导的阿尔茨海默病动物模型中改善成年大鼠的记忆与认知功能。
T35746 Milbemycin A3

Milbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A3 is used as a nematocide and insecticide. The acaricidal and nematocidal activity of a mixture of milbemycin A3 and milbemycin A4 against adult spider mites, spider mite eggs, and C. elegans are rep...
T35745 Marcfortine A

Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subuni...
T37275 2,3-dinor-11β-Prostaglandin F2α

2,3-dinor-11β-Prostaglandin F2α

2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α wh...
T35552 Ganglioside GD3 Mixture (sodium salt)

Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increa...
T80167 αC-Conotoxin PrXA

αC-PrXA

αC-Conotoxin PrXA为麻痹肽类神经毒素,亦是竞争性nAChR拮抗剂,对α1β1εδ(成人型)和α1β1γδ(胎儿型)nAChR的IC50值分别为1.8 nM和3.0 nM。该化合物通过与α-bungarotoxin竞争nAChR的α/δ及α/γ亚基界面,展现出对神经肌肉型nAChR的高度特异性。
T82357 GABA receptor Antagonist 1

GABA Receptor Membrane transporter/Ion channel; Neuroscience
GABA receptorAntagonist 1 (compound 7w) 在抑制PxRDL1GABAR方面具有高特异性,IC50为7.08 nmol/L。针对P. xylostella、S. frugiperda、S. exigua和S. litura的杀虫活性显著,相应的LC50值分别为0.09、0.84、0.87和0.68 mg/L。此化合物对蜜蜂的急性毒性为中等(48小时,LD50=2.22μg/成虫),而对斑马鱼的急性毒性较低(LC50: 42.4mg/L)。
T70186 Methazolamide-d6

Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and re...
T70070 Cisapride tartrate

Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisapride was indicated for the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease. The Food and Drug Administration (FDA) in America stopped the marketing of cisapride as of 14th July 2000. They had received at least 341 reports o...
T73677 SR 142948 dihydrochloride

SR 142948 dihydrochloride是一种口服活性高、选择性强的非肽类神经降压素受体(NT)拮抗剂,其在h-NTR1-CHO细胞、HT-29细胞和成年大鼠脑中IC50分别为1.19 nM、0.32 nM、3.96 nM。在HT-29细胞中,该化合物能够有效拮抗NT诱导的肌醇单磷酸盐形成,IC50为3.9 nM。此外,SR 142948 dihydrochloride在体内能够阻断NT诱导的体温下降、镇痛和转向行为,且具有良好的血脑屏障通透性,适用于精神疾病研究。
T37052 Tetranactin

Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold greater for lithium than sodium or cesium ions accross bilayer membranes at low voltages. Tetranactin inhibits the growth of Gram-positive bacteria and C. miyabeanus and R. solani fungi when used at concentrations less than 0.9 μg/ml. Tetranactin (0.5-1.5 μg per insect) dose-depen...
T38217 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE

1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid and adrenic acid at thesn-1 andsn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.1 1.Hancock, S.E., Friedrich, M.G., Mitchell, T.W., et al.Decreases in phospholipids containing adrenic and arachidonic acids occur in the human hippocampus over the adult lifespanLipids50(9)861-872(2015)
T37702 Pancuronium (bromide hydrate)

Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a non-depolarizing neuromuscular blocking agent.2Pancuronium enhances anesthesia induced by isoflurane , reducing immobilization with an ED50value of 1.62 μg/kg.3 1.Liu, M., and Dilger, J.P.Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholin...
T37094 (S)-UFR2709 hydrochloride

(S)-UFR2709 hydrochloride

(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction[1][2]. Brain nicotinic acetylcholine receptors (nAChRs) is a heterogeneous family of pentameric acetylcholine-gated cation channels, whi...

化合物

P-1075
Cat.No: T16420
Synonym:
Target: Potassium Channel
Neuropathiazol
Cat.No: T16288
Synonym:
Target: Others
Nomifensine maleate
Cat.No: T7070
Synonym: Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat
Target: Dopamine Receptor
CYM5181
Cat.No: T31149
Synonym: CYM 5181,CYM-5181
Target:
CX717
Cat.No: T60201
Synonym:
Target: GluR
Olodanrigan
Cat.No: T4431
Synonym: PD-126055,EMA401
Target: RAAS
Berzosertib
Cat.No: T2669
Synonym: VX-970,VE-822
Target: ATM/ATR
Quinabactin
Cat.No: T24695
Synonym: LC-66C6,ABA mimics 1,AM1,LC66C6,LC 66C6
Target: Others
Nitroxynil
Cat.No: T37072
Synonym: 4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix
Target: Parasite
GSK J5
Cat.No: T22821
Synonym: GSK-J5,GSKJ5
Target: Histone Demethylase
PY-60
Cat.No: T9566
Synonym:
Target: Annexin A, YAP
Tallimustine HCl
Cat.No: T68151L
Synonym: Tallimustine HCl(115308-98-0 Free base)
Target: DNA
Oxazolone
Cat.No: T5095
Synonym: 4-乙氧基亚甲基-2-苯基-2-唑啉-5-酮,4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
Target: Others
Mogamulizumab
Cat.No: T76782
Synonym: KW-0761
Target: CXCR
Betrixaban
Cat.No: T4341
Synonym: 贝曲西班,PRT054021
Target: Factor Xa
DSP-4 hydrochloride
Cat.No: T13664
Synonym: Neurotoxin DSP 4 (hydrochloride)
Target: Others
C3a Receptor Agonist
Cat.No: T38287
Synonym: C3a receptor agonist 1,C3a受体激动剂,Complement 3a Receptor Agonist
Target: Complement System
Isomer-Turosteride
Cat.No: T71703L
Synonym: Isomer-Turosteride(Isomer-137099-09-3)
Target: Reductase
Betrixaban maleate
Cat.No: T4980
Synonym:
Target: Factor Xa
Schnurri-3 inhibitor-1
Cat.No: T60554
Synonym:
Target: Others
Thiacloprid
Cat.No: T38272
Synonym:
Target: AChR, Parasite
l-trans-Phenothrin
Cat.No: T32908
Synonym:
Target:
Phenothrin
Cat.No: T1200
Synonym: 苯醚菊酯,Sumithrin
Target: Parasite
CD2019
Cat.No: T70647
Synonym:
Target:
Luxabendazole
Cat.No: T20960
Synonym: HOE 216V
Target:
AL-1
Cat.No: T29809
Synonym: AL 1,AL1
Target:
MGK-264
Cat.No: T20906
Synonym: NSC 36678,NSC 406879,ENT 8184
Target:
Petromyzonol
Cat.No: T37798
Synonym:
Target:
HDAC8-IN-2
Cat.No: T61549
Synonym:
Target:
Camoteskimab
Cat.No: T76938
Synonym:
Target:
16α-hydroxy Dehydroepiandrosterone
Cat.No: T36920
Synonym:
Target:
C19 Ceramide (d18:1/19:0)
Cat.No: T35873
Synonym: C19 Ceramide (d18:1/19:0)
Target:
Macimorelin acetate
Cat.No: T68276
Synonym: EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate
Target:
Anacardic Acid Diene
Cat.No: T35487
Synonym:
Target:
IIIM-8
Cat.No: T79378
Synonym:
Target: Melanocortin Receptor
αA-Conotoxin PIVA
Cat.No: T80486
Synonym:
Target:
TZ4M
Cat.No: T79621
Synonym:
Target:
Milbemycin A3
Cat.No: T35746
Synonym:
Target:
Marcfortine A
Cat.No: T35745
Synonym:
Target:
2,3-dinor-11β-Prostaglandin F2α
Cat.No: T37275
Synonym: 2,3-dinor-11β-Prostaglandin F2α
Target:
Ganglioside GD3 Mixture (sodium salt)
Cat.No: T35552
Synonym:
Target:
αC-Conotoxin PrXA
Cat.No: T80167
Synonym: αC-PrXA
Target:
GABA receptor Antagonist 1
Cat.No: T82357
Synonym:
Target: GABA Receptor
Methazolamide-d6
Cat.No: T70186
Synonym:
Target:
Cisapride tartrate
Cat.No: T70070
Synonym:
Target:
SR 142948 dihydrochloride
Cat.No: T73677
Synonym:
Target:
Tetranactin
Cat.No: T37052
Synonym:
Target:
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE
Cat.No: T38217
Synonym:
Target:
Pancuronium (bromide hydrate)
Cat.No: T37702
Synonym:
Target:
(S)-UFR2709 hydrochloride
Cat.No: T37094
Synonym: (S)-UFR2709 hydrochloride
Target:
Cat. No. Product Name Target Signaling Pathways
T19189 Allocholic acid

Others Others
Allocholic acid 是一种胆汁酸,在脊椎动物中发现,在肝脏再生和致癌过程中会重新出现,也是成熟嗅觉系统的特定性刺激物。
T5253 3-Methyladipic acid

Others; Endogenous Metabolite Metabolism; Others
3-Methyladipic acid 是 ω 氧化途径的终产物。它是植烷酸分解代谢的代谢物。
T7044 Norepinephrine

去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome
Norepinephrine (Levophed) 是β1选择性的肾上腺素能受体激动剂,EC50值为 5.37 μM。它可上调鼻咽癌肿瘤细胞中血管内皮生长因子、基质金属蛋白酶MMP-2和MMP-9的表达。
T4776 Glycerol

Glycerin,甘油

Endogenous Metabolite Metabolism
Glycerol 是甘油三酯(即脂肪和油)和磷脂的重要成分。它在食品工业中被广泛用作甜味剂和保湿剂以及药物制剂。
TL0012 Shyobunone

Others Others
Shyobunone and isoshyobunone have insecticidal and repellant activity, they exhibit strong contact toxicity against Lasioderma serricorne (LS adults with LD50 values of 20.24 and 24.19 ug/adult, respectively; they are strongly repellent against Tribolium
TN6453 Nardoaristolone B

Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophilanes and nardoaristolone B which s
T83440 17-Hydroxyjolkinolide A

Caudicifolin,Fischeriana A

17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) 是一种从大戟根中提取的昆虫摄食抑制剂。它能有效诱导玉米夜蛾 (S. zeamais) 与赤霉成虫 (T. castaneum) 对谷物产生拒食行为,其EC50s 值分别为 631.9 ppm 和 656.5 ppm。
T35758 Butyrolactone V

Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM).2,1 Butyrolactone V (227 and 454.1 μM) is also active against adult S. mansoni worms.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS radicals with IC50 values of 20.7 and 3.7 μM, respectively, in cell-free assays.3 Butyrolactone V also...
T37810 6',7'-Epoxybergamottin

6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...

天然产物

Allocholic acid
Cat.No: T19189
Synonym:
Target: Others
3-Methyladipic acid
Cat.No: T5253
Synonym:
Target: Others, Endogenous Metabolite
Norepinephrine
Cat.No: T7044
Synonym: 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol
Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy
Glycerol
Cat.No: T4776
Synonym: Glycerin,甘油
Target: Endogenous Metabolite
Shyobunone
Cat.No: TL0012
Synonym:
Target: Others
Nardoaristolone B
Cat.No: TN6453
Synonym:
Target:
17-Hydroxyjolkinolide A
Cat.No: T83440
Synonym: Caudicifolin,Fischeriana A
Target:
Butyrolactone V
Cat.No: T35758
Synonym:
Target:
6',7'-Epoxybergamottin
Cat.No: T37810
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-06022 FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)

folate receptor 1 (adult)

Cynomolgus,Rhesus HEK293 Cells
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is A0A2K5UR19&NP_001181576.1.
TMPY-01815 FOLR1 Protein, Human, Recombinant (His)

FBP,Folate Binding Protein,folate receptor 1 (adult...

Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A0A024R5H1.
TMPY-01803 FOLR1 Protein, Mouse, Recombinant (His)

folate receptor 1 (adult),Folbp1,FBP1,Folbp-1

Mouse HEK293 Cells
FOLR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P35846.
TMPY-02417 FOLR1 Protein, Canine, Recombinant (hFc)

folate receptor 1 (adult)

Canine HEK293 Cells
FOLR1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is A0A8C0Z2T7.
TMPJ-00147 FOLR1 Protein, Human, Recombinant (hFc)

Folate receptor 1,Folate receptor,Folate receptor alpha,FOLR...

Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328.
TMPY-00622 FOLR1 Protein, Canine, Recombinant (His)

folate receptor 1 (adult)

Canine HEK293 Cells
FOLR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0A8C0Z2T7.
TMPY-00543 FOLR1 Protein, Rat, Recombinant (His)

folate receptor 1 (adult)

Rat HEK293 Cells
FOLR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is G3V8M6.
TMPY-04128 FOLR1 Protein, Rat, Recombinant (hFc)

folate receptor 1 (adult)

Rat HEK293 Cells
FOLR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the accession number is G3V8M6.
TMPY-06929 FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated

Folate Binding Protein,folate receptor 1 (adult),FO...

Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.83 kDa and the accession number is NP_057937.1.
TMPY-06928 FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

FOLR,Folate Binding Protein,folate receptor 1 (adult

Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.11 kDa and the accession number is NP_057937.1.
TMPH-03426 Rotavirus X (isolate novel adult diarrhea rotavirus-B219) VP4 Protein (His)

RVX P. pastoris (Yeast)
Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. It is subsequently lost, together with VP7, following virus entry into the host cell. Following entry into the host cell, low intracellular o...
TMPJ-00148 FOLR1 Protein, Rhesus macaque, Recombinant (His)

FR-alpha,Adult folate-binding protein,Ovarian tumor...

Rhesus HEK293 Cells
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60.
TMPY-05033 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)

5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4

Human HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641.
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi)

血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,VPF,...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant

BDNF,Abrineurin,Brain-Derived Neurotrophic Factor

Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ...
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-05510 BDNF Protein, Mouse, Recombinant (His)

brain-derived neurotrophic factor

Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPJ-00071 EPO/Erythropoietin Protein, Human, Recombinant (His)

Erythropoietin,EPO,红细胞生长素,Epoetin

Human HEK293 Cells
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His)

Nog,Noggin

Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi...
TMPK-00861 A2AR Protein-VLP, Human, Recombinant

RDC8,Adenosine A2a R,ADORA2,ADORA 2,ADORA2A,A2aR

Human HEK293 Cells
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult.
TMPJ-01241 DTD1 Protein, Human, Recombinant (His)

DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-...

Human HEK293 Cells
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens...
TMPK-01239 THSD7A Protein, Human, Recombinant (His)

KIAA0960,thrombospondin,type I,domain containing 7A,Gm837,Th...

Human HEK293 Cells
Thrombospondin type I domain-containing 7A (THSD7A), is a specific autoantigen of adult idiopathic membranous nephropathy (IMN), whose circulating antibody (THSD7A-AB) represents a promising biomarker for diagnosis of IMN.
TMPJ-00663 GDF-8 Protein, Human/Mouse/Rat, Recombinant

骨肉瘤源生长因子,Gdf8,Mstn,GDF-8,Growth/differentiation factor 8,Myo...

Human,Mouse,Rat HEK293 Cells
Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically a...
TMPY-03063 SLITRK6 Protein, Human, Recombinant (His)

SLIT and NTRK like family member 6,SLITRK6,DFNMYP

Human HEK293 Cells
SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domains. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. It can sup...
TMPK-00868 Notch 4 Protein, Mouse, Recombinant (His)

Notch-4,Int-3,Notch4,Int3

Mouse HEK293 Cells
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells.
TMPJ-00666 CLIC2 Protein, Human, Recombinant (His)

CLIC2,XAP121,Chloride Intracellular Channel Protein 2

Human E. coli
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be d...
TMPY-06214 5T4/TPBG Protein, Mouse, Recombinant (hFc)

trophoblast glycoprotein,AW495680,5T4,WAIF1

Mouse HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9Z0L0.
TMPY-06191 5T4/TPBG Protein, Mouse, Recombinant (His)

trophoblast glycoprotein,WAIF1,5T4,AW495680

Mouse HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9Z0L0.
TMPK-00826 VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA,VPF,MVCD1,VEGF,...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPJ-00681 EDIL3 Protein, Human, Recombinant (His)

EGF-Like Repeats and Discoidin I-Like Domains 3,EDIL3

Human HEK293 Cells
EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence a...
TMPY-06317 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)

trophoblast glycoprotein,WAIF1,5T4AG,M6P1,5T4

Human HEK293 Cells
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.15 kDa and the accession number is NP_006661.1.
TMPH-03252 BCAN Protein, Rat, Recombinant (hFc)

Bcan,Behab,BEHAB,Brevican core protein,Brain-enriched hyalur...

Rat HEK293 Cells
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Isoform 2 may function as a chondroitin sulfate-bearing cell surface receptor. BCAN Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFC tag. The predicted molecular weight is 44 kDa and the accession number is P55068.
TMPH-03253 BCAN Protein, Rat, Recombinant (His & Myc)

Brevican core protein,Behab,Bcan,Brain-enriched hyaluronan-b...

Rat Baculovirus Insect Cells
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Isoform 2 may function as a chondroitin sulfate-bearing cell surface receptor. BCAN Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 19 kDa and the accession number is P55068.
TMPK-00825 VEGF121 Protein, Human, Recombinant (His & Avi)

VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70609,RP1-261G23.1,M...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPK-00822 VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,VAS,MVCD1,...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPH-02430 SNCG Protein, Cynomolgus, Recombinant

Cynomolgus E. coli
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. SNCG Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.3 kDa and the accession number is Q2P...
TMPY-02578 DKKL1 Protein, Human, Recombinant (hFc)

SGY,dickkopf-like 1,CT34,SGY1,SGY-1

Human HEK293 Cells
Dickkopf-like 1 (DKKL1) or soggy 1, is a glycoprotein unique to mammals that is expressed primarily in developing spermatocytes and localized in the acrosome of mature sperm. It is also expressed in the trophectoderm / placental lineage. This glycoprotein is secreted by postmeiotic male germ cells. DKKL1 is a member of the Dickkopf (DKK) family, a group of proteins that are characterized as secreted antagonists of Wnt signal transduction proteins. In mammals, embryos lacking DKKL1 protein develo...
TMPH-01370 SNCG Protein, Human, Recombinant (His & SUMO)

Human E. coli
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. SNCG Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.3 kDa a...
TMPJ-00656 SULT1C2 Protein, Human, Recombinant (His)

Sulfotransferase 1C1,humSULTC2,SULT1C1,Sulfotransferase 1C2,...

Human E. coli
Sulfotransferase 1C2 (SULT1C2) is a cytosolic enzyme member of the Sulfotransferase 1 family. Human SULT1C2 is primarily expressed in the adult stomach, kidney and thyroid gland, and in the fetal kidney and liver. SULT1C2 catalyzes the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. SULT1C2 may be involved in the activation of carcinogenic hyroxylamines. It shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).
TMPJ-01003 STAT5B Protein, Human, Recombinant (His)

Signal Transducer and Activator of Transcription 5B,STAT5B

Human E. coli
Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adul...
TMPY-04118 Livin/BIRC7 Protein, Human, Recombinant (His)

MLIAP,baculoviral IAP repeat containing 7,RNF50,KIAP,ML-IAP,...

Human E. coli
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecu...
TMPY-01165 FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)

Fzd1,AW227548,frizzled class receptor 1,FZ-1,Fz1

Mouse HEK293 Cells
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signalin...
TMPY-01843 SEMA6A Protein, Human, Recombinant (His)

HT018,VIA,sema domain, transmembrane domain (TM), and cytopl...

Human HEK293 Cells
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SEMA6A may be a potential prognostic biomarker in the treatment of GBM. Among different semaphorins tested by reverse transcriptase-polymerase chain reaction in human immune cells, the expression of class 6 transmembrane semaphorin SEMA6A was restricted to dendritic cells (DCs).
TMPJ-00491 BCAN Protein, Human, Recombinant (His)

Chondroitin Sulfate Proteoglycan 7,BCAN,CSPG7,BEHAB,Brain-En...

Human HEK293 Cells
Brevican Core Protein (BCAN) is a secreted protein that belongs to the aggrecan/versican proteoglycan family. BCAN contains one C-type lectin domain, one EGF-like domain, one Ig-like V-type domain, one Sushi (CCP/SCR) domain and two Link domains. BCAN may play a role in the terminally differentiating and the adult nervous system during postnatal development. BCAN could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
TMPJ-01156 PHLDA2 Protein, Human, Recombinant (His)

Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate G...

Human E. coli
Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present in all cells of the villous cytotrophoblast. PHLDA2 plays a role in regulating placenta growth. PHLDA2 may act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.
TMPJ-00348 CD316 Protein, Human, Recombinant (hFc)

KCT-4,EWI2,CD81P3,CD316,IGSF8,Glu-Trp-Ile EWI Motif-Containi...

Human HEK293 Cells
Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.
TMPJ-00752 HBAZ Protein, Human, Recombinant (His)

Hemoglobin Subunit Zeta,Hemoglobin ζ Chain,Hemoglobin Zeta C...

Human E. coli
Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal growth and adult life. The HBZ gene consists of five functional genes and two pseudogenes, the order of genes is 5-zeta-pseudozeta-mu-pseudoalpha-1-alpha-2-alpha-1-theta-1-3.
TMPK-00945 ASPH Protein, Human, Recombinant (His)

Aspartate beta-hydroxylase,ASP beta-hydroxylase,Asph,Bah,Asp...

Human E. coli
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH...
TMPK-01226 DKK3 Protein, Human, Recombinant (His & Avi)

AW061014,REIC,REICdkk-3,C87148,Dkk3,RIG,Dickkopf-3,RIG-like ...

Human HEK293 Cells
Dkk-3, also known as REIC (Reduced Expansion in Immortalized Cells), is one of four numbered members of the Dickkopf family of Wnt antagonists.DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. DKK3 Protein, Human, Recombinant (His & Avi) is expressed...
TMPK-01083 ASPH Protein, Mouse, Recombinant (His)

Aspartate β-hydroxylase,ASP β-hydroxylase,Aspartate beta-hyd...

Mouse E. coli
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH...
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重组蛋白

FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06022
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01815
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01803
Species: Mouse
Expression System: HEK293 Cells
FOLR1 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-02417
Species: Canine
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00147
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Canine, Recombinant (His)
Cat.No: TMPY-00622
Species: Canine
Expression System: HEK293 Cells
FOLR1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-00543
Species: Rat
Expression System: HEK293 Cells
FOLR1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04128
Species: Rat
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06929
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06928
Species: Human
Expression System: HEK293 Cells
Rotavirus X (isolate novel adult diarrhea rotavirus-B219) VP4 Protein (His)
Cat.No: TMPH-03426
Species: RVX
Expression System: P. pastoris (Yeast)
FOLR1 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00148
Species: Rhesus
Expression System: HEK293 Cells
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
Cat.No: TMPY-05033
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00823
Species: Human
Expression System: HEK293 Cells
BDNF Protein, Human/Murine/Rat, Recombinant
Cat.No: TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
BDNF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
EPO/Erythropoietin Protein, Human, Recombinant (His)
Cat.No: TMPJ-00071
Species: Human
Expression System: HEK293 Cells
Noggin/NOG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
A2AR Protein-VLP, Human, Recombinant
Cat.No: TMPK-00861
Species: Human
Expression System: HEK293 Cells
DTD1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01241
Species: Human
Expression System: HEK293 Cells
THSD7A Protein, Human, Recombinant (His)
Cat.No: TMPK-01239
Species: Human
Expression System: HEK293 Cells
GDF-8 Protein, Human/Mouse/Rat, Recombinant
Cat.No: TMPJ-00663
Species: Human,Mouse,Rat
Expression System: HEK293 Cells
SLITRK6 Protein, Human, Recombinant (His)
Cat.No: TMPY-03063
Species: Human
Expression System: HEK293 Cells
Notch 4 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00868
Species: Mouse
Expression System: HEK293 Cells
CLIC2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00666
Species: Human
Expression System: E. coli
5T4/TPBG Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-06214
Species: Mouse
Expression System: HEK293 Cells
5T4/TPBG Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06191
Species: Mouse
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00826
Species: Human
Expression System: HEK293 Cells
EDIL3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00681
Species: Human
Expression System: HEK293 Cells
5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)
Cat.No: TMPY-06317
Species: Human
Expression System: HEK293 Cells
BCAN Protein, Rat, Recombinant (hFc)
Cat.No: TMPH-03252
Species: Rat
Expression System: HEK293 Cells
BCAN Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03253
Species: Rat
Expression System: Baculovirus Insect Cells
VEGF121 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00825
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00822
Species: Human
Expression System: HEK293 Cells
SNCG Protein, Cynomolgus, Recombinant
Cat.No: TMPH-02430
Species: Cynomolgus
Expression System: E. coli
DKKL1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02578
Species: Human
Expression System: HEK293 Cells
SNCG Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01370
Species: Human
Expression System: E. coli
SULT1C2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00656
Species: Human
Expression System: E. coli
STAT5B Protein, Human, Recombinant (His)
Cat.No: TMPJ-01003
Species: Human
Expression System: E. coli
Livin/BIRC7 Protein, Human, Recombinant (His)
Cat.No: TMPY-04118
Species: Human
Expression System: E. coli
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01165
Species: Mouse
Expression System: HEK293 Cells
SEMA6A Protein, Human, Recombinant (His)
Cat.No: TMPY-01843
Species: Human
Expression System: HEK293 Cells
BCAN Protein, Human, Recombinant (His)
Cat.No: TMPJ-00491
Species: Human
Expression System: HEK293 Cells
PHLDA2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01156
Species: Human
Expression System: E. coli
CD316 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00348
Species: Human
Expression System: HEK293 Cells
HBAZ Protein, Human, Recombinant (His)
Cat.No: TMPJ-00752
Species: Human
Expression System: E. coli
ASPH Protein, Human, Recombinant (His)
Cat.No: TMPK-00945
Species: Human
Expression System: E. coli
DKK3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01226
Species: Human
Expression System: HEK293 Cells
ASPH Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01083
Species: Mouse
Expression System: E. coli
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