Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family. 8-methyl Nonanoicacid is an immediate precursor of capsaicin as well as a by-product of capsaicin degradation.[1] Addition of 5 mM of 8-methyl nonanoicacid significantly increases the yield of capsaicin in both immobilized and freely suspended cells of C. frutescens. [2] Capsaicin has reported antimicrobial properties, however isocapric acid can act as a growth substrate in certain bacterial strains.[3]
9-(Boc-amino)nonanoicAcid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
3-Hydroxy NonanoicAcid, a hydroxylated fatty acid, is present in the young peridioles of Pisolithus fungi, LPS of P. aeruginosa, bovine milk, and the methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers synthesized by P. oleovorans [Matreya, LLC. Catalog No. 1725].
7-methyl-8-oxononanoicacid is an intermidate for synthesis of conjugated molecules. The acid group can derivatize amine-containing molecules in the presence of activators such as EDC or HATU.
Fmoc-9-aminononanoicacid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and and other conjugation applications. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Tripelargonin is a triacylglycerol that contains nonanoicacid at the sn-1, sn-2, and sn-3 positions. It has been found in Schizochytrium biomass.1 Tripelargonin increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in newborn rhesus monkeys.2