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73

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
TNU0952 2’-Fluoro-5MeC   (Bz)-3’-phosphoramidite

2'-Fluoro-5MeC (Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite.
T75225 Rev 2’-O-MOE-5MeC(Bz)-5’-amidite

Rev 2’-O-MOE-5MeC(Bz)-5’-amidite 是一种嘌呤核苷类似物,广泛应用于靶向惰性淋巴系统恶性肿瘤的抗癌研究中。其抗肿瘤机制主要通过抑制 DNA 合成和诱导细胞凋亡 (apoptosis) 实现。
T2006 Omecamtiv mecarbil

CK-1827452

ATPase; Myosin Cytoskeletal Signaling; Membrane transporter/Ion channel
Omecamtiv mecarbil (CK-1827452) 是一种心脏特异性的肌球蛋白激活剂,用于研究心脏相关疾病。
T4059 Selamectin

UK-124114,司拉克丁,塞拉菌素

Chloride channel; P-gp; Parasite Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Selamectin (UK-124114) 是半合成的大环内酯,是一种驱虫剂,可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂,可激活神经元和咽肌中的谷氨酸门控氯离子通道,以预防恶丝虫,淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂,IC50为 120 nM。
T60055 Chromeceptin

2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile

Akt; IGF-1R; mTOR Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Chromeceptin 是 IGF 信号通路的抑制剂,可减少肿瘤球的数量,并抑制 AKT/mTOR 通路。
T67758 Pumecitinib

JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
Pumecitinib 是一种Janus 激酶(JAK)抑制剂。Pumecitinib 显示出抗炎活性。
T21727 Ivermectin B1a

SARS-CoV; Parasite Microbiology/Virology
Ivermectin B1a 是 Avermectin B1a 的一种衍生物,是 Ivermectin 的主要成分。Ivermectin 是广谱的抗寄生虫剂。Ivermectin 也是抗 SARS-CoV-2/COVID-19 的候选药物。
T7560 Pivmecillinam hydrochloride

匹美西林盐酸盐,FL-1039 hydrochloride,盐酸匹美西林

Antibacterial; Antibiotic Microbiology/Virology
Pivmecillinam hydrochloride (FL-1039 hydrochloride) 是Mecillinam 的口服活性前药,是一种广谱青霉素抗生素,对革兰氏阴性菌有活性,可用作氨苄青霉素。
T5836 Eprinomectin

依普菌素,MK-397

Parasite Microbiology/Virology
Eprinomectin (MK-397) 是一种阿维菌素,具有驱虫,杀虫杀螨活性。
T40652 Meclizine

Meclozine

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Meclizine (Meclozine) (Meclozine)具有抗组胺作用,可可逆地抑制组胺与H1受体的相互作用。Meclizine 是哌嗪类H1拮抗剂的一个成员。Meclizine 是一种有效的抗运动病剂。Meclizine 可通过血脑屏障。Meclizine 是小鼠组成型雄烷受体(CAR)的激动剂配体,也是人CAR 的反向激动剂。Meclizine 可用于polyQ 毒性疾病的研究,如亨廷顿病。
T1110 Meclizine dihydrochloride

Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪

Apoptosis; Histamine Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Meclizine dihydrochloride (NSC28728) 是一种组胺 H1 拮抗剂,用于治疗妊娠期间的晕动病、眩晕和恶心以及放射病。它是小鼠组成型雄甾烷受体激动剂,是人 CAR 的反向激动剂。它可透过血脑屏障,可用于多聚谷氨酰胺毒性障碍方面的研究。
T2648 Pimecrolimus

SDZ-ASM 981,ASM 981,吡美莫司

Others Others
Pimecrolimus (SDZ-ASM 981) 是一种免疫亲和素配体,能与胞质受体特异性的结合。
T21369 Mecillinam

Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX

Antibacterial Microbiology/Virology
Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。
T6801 CeMMEC13

Carboxypeptidase; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome
CeMMEC13 是一种异喹啉酮,可选择性抑制 TAF1 的第二个溴结构域,IC50为 2.1 μM。
T26726 AzddMeC

CS-92,Azidodideoxymethylcytidine,Az-Dcme

HIV Protease Microbiology/Virology; Proteases/Proteasome
AzddMeC (Az-Dcme) 是一种具有口服活性、高效性和选择性的 HIV-1 逆转录酶和 HIV-1 复制抑制剂,具有抗逆转录病毒活性。AzddMeC 可用于研究 HIV-1 感染。
T22489 2'-MeCCPA

2-Chloro-N-cyclopentyl-2′-C-methyladenosine

HCV Protease; Adenosine Receptor GPCR/G Protein; Microbiology/Virology; Neuroscience; Proteases/Proteasome
2'-MeCCPA 是一种具有有效性和高选择性的 A1 腺苷受体 (A1AR) 激动剂,对 AR 的 K 值为 1.8 nM。2'-MeCCPA 抑制毛喉素刺激的腺苷酸环化酶活性,IC值为13.1 nM。2'-MeCCPA 具有镇痛活性,可用于研究 HCV 。
T16034 Meclinertant

SR 48692

Others Others
Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in human colon carcinoma (HT-29) cell
T4345 CeMMEC1

CeMMEC1 HCl

Epigenetic Reader Domain; Carboxypeptidase; DNA/RNA Synthesis Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
CeMMEC1 是一种 BRD4 抑制剂,对 TAF1 有很好的亲和力,IC50为0.9 μM。
T4997 Umeclidinium bromide

芜地溴铵,GSK573719A

AChR Neuroscience
Umeclidinium bromide (GSK573719A) 是mAChR 拮抗剂,作用于克隆的人 M1-M5 mAChRs,Ki 为 0.05 到 0.16 nM。
T2141 Mecamylamine hydrochloride

盐酸美加明,Inversine,Mevasin

AChR Neuroscience
Mecamylamine hydrochloride (Mevasin) 是一种易穿过血脑屏障的烟碱拮抗剂,用作高血压的神经节阻滞剂,具有抗神经疾病作用。
T0013 Mecarbinate

优多降,Dimecarbine,Dimecarbin,美卡比酯

HCV Protease Microbiology/Virology; Proteases/Proteasome
Mecarbinate (Dimecarbin) 是抗 HCV 试剂,也是中间体。
T1401 Meclofenoxate hydrochloride

Meclofenoxate (Centrophenoxine) HCl,Lucidril,盐酸甲氯芬酯,Cerutil,盐酸甲氯酚酯,Meclofenoxate HCl

Lipoxygenase; COX; AChR; iGluR Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Meclofenoxate hydrochloride (Lucidril) 是二甲基氨基乙醇和对氯苯氧乙酸的酯,有刺激记忆和提高认知的活性。
T0260 Meclofenamic acid sodium

Meclofenamate Sodium,Movens,Meclomen,甲氯灭酸钠,Meclonax

Gap Junction Protein; COX Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience
Meclofenamic acid sodium (Movens) 是一种非甾体抗炎药,可用于治疗关节炎 、缓解疼痛、痛经和严重月经失血。它是一种非选择性的缝隙连接阻断剂,是一种高选择性的脂肪和肥胖相关酶抑制剂。
T7605 Avermectin B1a

阿维菌素 B1a,Abamectin B1a,Avamectin B1a

Antibiotic; Parasite Microbiology/Virology
Avermectin B1a 是能够使线虫瘫痪的一种抗寄生虫剂。
T15212 Emamectin Benzoate

MK-244,甲胺基阿维菌素苯甲酸盐

Apoptosis; Reactive Oxygen Species; GABA Receptor; Parasite Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
Emamectin Benzoate (MK-244) 是口服有效的神经系统毒物,其通过结合昆虫中的 GABA 受体发挥作用。它是阿维菌素的半合成衍生物之一,具有广谱的杀虫和杀螨活性。它诱导ROS 介导的 DNA 损伤和细胞凋亡。
T7213 Demecarium bromide

地美溴铵,BC-48

AChE Neuroscience
Demecarium bromide (BC-48) 是一种有效的cholinesterase 抑制剂,Kiapp=0.15 μM,它可用研究于青光眼。
T11990 Meclofenamic acid

甲氯芬那酸,Meclofenamate

Others; Gap Junction Protein Cytoskeletal Signaling; Others
Meclofenamic acid (Meclofenamate) 是一种非特异性 gap-junction 阻滞剂和特异性脂肪量和肥胖相关 (FTO) 酶抑制剂。 Meclofenamic acid 具有抗炎活性。
T0260L Meclofenamate sodium hydrate

INF 4668,CI583,CI-583,INF-4668,CI 583,INF4668

Meclofenamate sodium is a potent non-steroidal anti-inflammatory agent, which can specifically inhibit chemokine-induced human polymorphonuclear leukocyte function: chemotaxis, degranulation, and superoxide anion free radical production.
T70250 Demeclocycline calcium

Demeclocycline calcium is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.
T20632 Mecoprop

Mepro,Morogal,Mecprop,Methoxone,Mecoturf

Mecoprop is an herbicide used to control broadleaf weeds.
T24442 Mecrylate

Mecrylate polymerizes in contact with moisture. It is used as a tissue adhesive. It also has higher homologs have hemostatic and antibacterial properties.
T38512 2,3-Dehydro-3,4-dihydro ivermectin

2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes ( IC 50 s=13.8 and 3.6 μM, respectively) without inducing cytotoxicity to macrophages ( IC 50 = 65.5 μM).
TP2430 Cucumechinoside D

Cucumechinoside D is a natural bioactive chemical.
T39715 MeCY5-NHS ester potassium

Sulfo-Cyanine5 NHS ester potassium,MeCY5-NHS ester potassium

MeCY5-NHS ester (potassium) is a reactive dye designed for labeling proteins and nucleic acids.
T22874 Ivermectin B1a-d2

Others Others
Deuterated ivermectin B1a
T31893 Furmecyclox

BAS 389,BAS-389,BAS 389F,BAS389,GUS 215

Furmecyclox is a biochemical.
T71873 Temechine hydrobromide

Temechine hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors.
T14082 AB-MECA

Others Others
AB-MECA is a high affinity A3 adenosine receptor agonist. It has high affinity for recombinant A1 and A3 receptors.
T70311 Demecarium Free Base

Demecarium Free Base is a quaternary ammonium compound that serves as a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically, demecarium inactivates both pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown and increasing acetylcholine activity.
T24690 Pyrromecaine HCl

Bumecaine hydrochloride,Pyrromecaine

Pyrromecaine is a local anesthetic used for surface anesthesia. Pyromecaine has a wide spectrum of antiarrhythmic action, exerts a favorable effect on the contractility of the left ventricle, and on the myocardial blood flow following the ligation of the
T24641 Pimeclone hydrochloride

NU852,NSC 18727,NU 582,Pimeclone HCl,NU-582

Pimeclone hydrochloride is a psychostimulant or a respiratory stimulant drug.
T31815 Flumecinol

Zyxorin

Flumecinol is a hepatic enzyme (cytochrome P-450 monooxygenases) inducer.
T24881 Thymectacin

NB 1011,NB-1011,NB1011

Thymectacin is a small molecule phosphoramidite derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine with potential antineoplastic activity.
T35756 Avermectin B1a monosaccharide

Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a . It is lethal to C. elegans with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a monosaccharide also stimulates conductance in isolated shore crab muscle.
T35733 Doramectin aglycone

Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.
T125077 Mecambridine

Mecambridine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125077。
T32016 Guamecycline

Guamecyclinum,Guameciclina

Guamecycline is a biochemical.
T35755 Avermectin B1a aglycone

Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance.
T64965 Avermectin

Avermectin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64965。
T31401 S-(+)-Mecamylamine hydrochloride

NIH-11008,TC-5214,Dexmecamylamine HCl,NIH11008,TC 5214,NIH 11008,TC5214

Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.

化合物

2’-Fluoro-5MeC   (Bz)-3’-phosphoramidite
Cat.No: TNU0952
Synonym:
Target:
Rev 2’-O-MOE-5MeC(Bz)-5’-amidite
Cat.No: T75225
Synonym:
Target:
Omecamtiv mecarbil
Cat.No: T2006
Synonym: CK-1827452
Target: ATPase, Myosin
Selamectin
Cat.No: T4059
Synonym: UK-124114,司拉克丁,塞拉菌素
Target: Chloride channel, P-gp, Parasite
Chromeceptin
Cat.No: T60055
Synonym: 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
Target: Akt, IGF-1R, mTOR
Pumecitinib
Cat.No: T67758
Synonym:
Target: JAK
Ivermectin B1a
Cat.No: T21727
Synonym:
Target: SARS-CoV, Parasite
Pivmecillinam hydrochloride
Cat.No: T7560
Synonym: 匹美西林盐酸盐,FL-1039 hydrochloride,盐酸匹美西林
Target: Antibacterial, Antibiotic
Eprinomectin
Cat.No: T5836
Synonym: 依普菌素,MK-397
Target: Parasite
Meclizine
Cat.No: T40652
Synonym: Meclozine
Target: Histamine Receptor
Meclizine dihydrochloride
Cat.No: T1110
Synonym: Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪
Target: Apoptosis, Histamine Receptor
Pimecrolimus
Cat.No: T2648
Synonym: SDZ-ASM 981,ASM 981,吡美莫司
Target: Others
Mecillinam
Cat.No: T21369
Synonym: Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX
Target: Antibacterial
CeMMEC13
Cat.No: T6801
Synonym:
Target: Carboxypeptidase, DNA/RNA Synthesis
AzddMeC
Cat.No: T26726
Synonym: CS-92,Azidodideoxymethylcytidine,Az-Dcme
Target: HIV Protease
2'-MeCCPA
Cat.No: T22489
Synonym: 2-Chloro-N-cyclopentyl-2′-C-methyladenosine
Target: HCV Protease, Adenosine Receptor
Meclinertant
Cat.No: T16034
Synonym: SR 48692
Target: Others
CeMMEC1
Cat.No: T4345
Synonym: CeMMEC1 HCl
Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis
Umeclidinium bromide
Cat.No: T4997
Synonym: 芜地溴铵,GSK573719A
Target: AChR
Mecamylamine hydrochloride
Cat.No: T2141
Synonym: 盐酸美加明,Inversine,Mevasin
Target: AChR
Mecarbinate
Cat.No: T0013
Synonym: 优多降,Dimecarbine,Dimecarbin,美卡比酯
Target: HCV Protease
Meclofenoxate hydrochloride
Cat.No: T1401
Synonym: Meclofenoxate (Centrophenoxine) HCl,Lucidril,盐酸甲氯芬酯,Cerutil,盐酸甲氯酚酯,Meclofenoxate HCl
Target: Lipoxygenase, COX, AChR, iGluR
Meclofenamic acid sodium
Cat.No: T0260
Synonym: Meclofenamate Sodium,Movens,Meclomen,甲氯灭酸钠,Meclonax
Target: Gap Junction Protein, COX
Avermectin B1a
Cat.No: T7605
Synonym: 阿维菌素 B1a,Abamectin B1a,Avamectin B1a
Target: Antibiotic, Parasite
Emamectin Benzoate
Cat.No: T15212
Synonym: MK-244,甲胺基阿维菌素苯甲酸盐
Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite
Demecarium bromide
Cat.No: T7213
Synonym: 地美溴铵,BC-48
Target: AChE
Meclofenamic acid
Cat.No: T11990
Synonym: 甲氯芬那酸,Meclofenamate
Target: Others, Gap Junction Protein
Meclofenamate sodium hydrate
Cat.No: T0260L
Synonym: INF 4668,CI583,CI-583,INF-4668,CI 583,INF4668
Target:
Demeclocycline calcium
Cat.No: T70250
Synonym:
Target:
Mecoprop
Cat.No: T20632
Synonym: Mepro,Morogal,Mecprop,Methoxone,Mecoturf
Target:
Mecrylate
Cat.No: T24442
Synonym:
Target:
2,3-Dehydro-3,4-dihydro ivermectin
Cat.No: T38512
Synonym:
Target:
Cucumechinoside D
Cat.No: TP2430
Synonym:
Target:
MeCY5-NHS ester potassium
Cat.No: T39715
Synonym: Sulfo-Cyanine5 NHS ester potassium,MeCY5-NHS ester potassium
Target:
Ivermectin B1a-d2
Cat.No: T22874
Synonym:
Target: Others
Furmecyclox
Cat.No: T31893
Synonym: BAS 389,BAS-389,BAS 389F,BAS389,GUS 215
Target:
Temechine hydrobromide
Cat.No: T71873
Synonym:
Target:
AB-MECA
Cat.No: T14082
Synonym:
Target: Others
Demecarium Free Base
Cat.No: T70311
Synonym:
Target:
Pyrromecaine HCl
Cat.No: T24690
Synonym: Bumecaine hydrochloride,Pyrromecaine
Target:
Pimeclone hydrochloride
Cat.No: T24641
Synonym: NU852,NSC 18727,NU 582,Pimeclone HCl,NU-582
Target:
Flumecinol
Cat.No: T31815
Synonym: Zyxorin
Target:
Thymectacin
Cat.No: T24881
Synonym: NB 1011,NB-1011,NB1011
Target:
Avermectin B1a monosaccharide
Cat.No: T35756
Synonym:
Target:
Doramectin aglycone
Cat.No: T35733
Synonym:
Target:
Mecambridine
Cat.No: T125077
Synonym:
Target:
Guamecycline
Cat.No: T32016
Synonym: Guamecyclinum,Guameciclina
Target:
Avermectin B1a aglycone
Cat.No: T35755
Synonym:
Target:
Avermectin
Cat.No: T64965
Synonym:
Target:
S-(+)-Mecamylamine hydrochloride
Cat.No: T31401
Synonym: NIH-11008,TC-5214,Dexmecamylamine HCl,NIH11008,TC 5214,NIH 11008,TC5214
Target:
Cat. No. Product Name Target Signaling Pathways
T0969 Doramectin

Dectomax,Cyclohexylavermectin B1,多拉菌素

Others; Antibiotic; Parasite Microbiology/Virology; Others
Doramectin (Dectomax) 是 Ivermectin 的衍生物。它是一种抗寄生虫抗生素。它具有在 NMRI 小鼠感染模型中抗曼氏链球菌作用。
T0956 Avermectin B1

Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素

Antibiotic; Parasite; Autophagy Autophagy; Microbiology/Virology
Avermectin B1 是驱虫杀虫剂。
T37508 Meconin

Endogenous Metabolite Metabolism
Meconine 是一种人内源性代谢产物。
TL0015 Pyromeconic acid

3-羟基-4氢-吡喃-4-酮,3-hydroxy-4H-pyran-4-one

Anti-infection Microbiology/Virology
Pyromeconic acid (3-hydroxy-4H-pyran-4-one) 及其衍生物是核酸内切酶的有效抑制剂
T1400 Demeclocycline hydrochloride

地美环素,Declomycin,Clortetrin,盐酸地美环素,Detravis,Demeclocycline HCl

ribosome; Antibacterial; Antibiotic Microbiology/Virology
Demeclocycline hydrochloride (Declomycin) 是四环素类抗生素,可治疗粉刺,莱姆病和支气管炎。
T0281 Meclocycline sulfosalicylate salt

磺基水杨酸甲氯环素,Meclutin,Mecloderm,甲环素磺基水杨酸盐,Meclan Cream

Antibacterial; Antibiotic Microbiology/Virology
Meclocycline sulfosalicylate salt (Mecloderm) 是一种具有广谱抗菌活性的四环素抗生素,可预防皮肤细菌感染。
T1131 Ivermectin

MK-933,伊维菌素

Mitophagy; GluCls; P2X Receptor; SARS-CoV; HIV Protease; Antibiotic; Parasite; Autophagy; HSV Autophagy; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Ivermectin (MK-933) 是谷氨酸门控氯离子通道激活剂,具有抗寄生虫活性。它特异性抑制Impα/β1 介导的核导入,还抑制牛疱疹病毒 1 复制并抑制BoHV-1DNA 聚合酶的核输入。它具有很强的抗病毒活性。它也是P2X4和 α7nAChRs 的正异构效应物。
T35743 Ivermectin B1a aglycone

Ivermectin B1a aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.
T40929 Mechercharmycin A

Mechercharmycin A, a cytotoxic compound, was isolated from Thermoactinomyces sp. YM3-251, a marine source. It demonstrates potent antitumor activity.
T11842 Levomecol

Others Others
Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthesis by blocking peptidyl transferase.
T35752 Xanthoquinodin A1

Xanthoquinodin A1

Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1Xanthoquinodin A1 is active againstB. subtilis,M. luteus,S. aureus,A. laidlawii, andB. fragilisin a disc assay when used at a concentration of 1 mg/ml. It is also active againstB. cereus(MIC = 0.44 μM).2Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cance...

天然产物

Doramectin
Cat.No: T0969
Synonym: Dectomax,Cyclohexylavermectin B1,多拉菌素
Target: Others, Antibiotic, Parasite
Avermectin B1
Cat.No: T0956
Synonym: Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素
Target: Antibiotic, Parasite, Autophagy
Meconin
Cat.No: T37508
Synonym:
Target: Endogenous Metabolite
Pyromeconic acid
Cat.No: TL0015
Synonym: 3-羟基-4氢-吡喃-4-酮,3-hydroxy-4H-pyran-4-one
Target: Anti-infection
Demeclocycline hydrochloride
Cat.No: T1400
Synonym: 地美环素,Declomycin,Clortetrin,盐酸地美环素,Detravis,Demeclocycline HCl
Target: ribosome, Antibacterial, Antibiotic
Meclocycline sulfosalicylate salt
Cat.No: T0281
Synonym: 磺基水杨酸甲氯环素,Meclutin,Mecloderm,甲环素磺基水杨酸盐,Meclan Cream
Target: Antibacterial, Antibiotic
Ivermectin
Cat.No: T1131
Synonym: MK-933,伊维菌素
Target: Mitophagy, GluCls, P2X Receptor, SARS-CoV, HIV Protease, Antibiotic, Parasite, Autophagy, HSV
Ivermectin B1a aglycone
Cat.No: T35743
Synonym:
Target:
Mechercharmycin A
Cat.No: T40929
Synonym:
Target:
Levomecol
Cat.No: T11842
Synonym:
Target: Others
Xanthoquinodin A1
Cat.No: T35752
Synonym: Xanthoquinodin A1
Target:
Cat. No. Product Name Species Expression System
TMPY-03728 CCL28 Protein, Human, Recombinant (His)

MEC,SCYA28,chemokine (C-C motif) ligand 28,CCK1

Human E. coli
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues an...
TMPJ-00019 CCL28 Protein, Human, Recombinant

Small-Inducible Cytokine A28,Protein CCK1,CCL28,SCYA28,C-C M...

Human E. coli
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expresse...
TMPJ-00460 MECR Protein, Human, Recombinant (His)

Nuclear Receptor-Binding Factor 1,HsNrbf-1NRBF-1,MEC

Human HEK293 Cells
Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain...
TMPH-03521 MecA Protein, S. aureus, Recombinant (His & SUMO)

Staphylococcus aureus E. coli
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P60186.
TMPH-03035 M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)

Myrmecia pilosula Baculovirus Insect Cells
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplant...
TMPJ-00998 MECP2 Protein, Human, Recombinant (His)

Methyl-CpG-binding protein 2,MeCp-2 protein,MEC...

Human HEK293 Cells
The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may ...
TMPH-02254 Trypsin-1 Protein, Human, Recombinant (His & Myc)

Human E. coli
Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.

重组蛋白

CCL28 Protein, Human, Recombinant (His)
Cat.No: TMPY-03728
Species: Human
Expression System: E. coli
CCL28 Protein, Human, Recombinant
Cat.No: TMPJ-00019
Species: Human
Expression System: E. coli
MECR Protein, Human, Recombinant (His)
Cat.No: TMPJ-00460
Species: Human
Expression System: HEK293 Cells
MecA Protein, S. aureus, Recombinant (His & SUMO)
Cat.No: TMPH-03521
Species: Staphylococcus aureus
Expression System: E. coli
M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)
Cat.No: TMPH-03035
Species: Myrmecia pilosula
Expression System: Baculovirus Insect Cells
MECP2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00998
Species: Human
Expression System: HEK293 Cells
Trypsin-1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02254
Species: Human
Expression System: E. coli
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