73
11
7
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TNU0952 |
2’-Fluoro-5MeC (Bz)-3’-phosphoramidite
|
||
2'-Fluoro-5MeC (Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite. | |||
T75225 | Rev 2’-O-MOE-5MeC(Bz)-5’-amidite | ||
Rev 2’-O-MOE-5MeC(Bz)-5’-amidite 是一种嘌呤核苷类似物,广泛应用于靶向惰性淋巴系统恶性肿瘤的抗癌研究中。其抗肿瘤机制主要通过抑制 DNA 合成和诱导细胞凋亡 (apoptosis) 实现。 | |||
T2006 |
Omecamtiv mecarbil
CK-1827452 |
ATPase; Myosin | Cytoskeletal Signaling; Membrane transporter/Ion channel |
Omecamtiv mecarbil (CK-1827452) 是一种心脏特异性的肌球蛋白激活剂,用于研究心脏相关疾病。 | |||
T4059 |
Selamectin
UK-124114,司拉克丁,塞拉菌素 |
Chloride channel; P-gp; Parasite | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
Selamectin (UK-124114) 是半合成的大环内酯,是一种驱虫剂,可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂,可激活神经元和咽肌中的谷氨酸门控氯离子通道,以预防恶丝虫,淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂,IC50为 120 nM。 | |||
T60055 |
Chromeceptin
2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile |
Akt; IGF-1R; mTOR | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors |
Chromeceptin 是 IGF 信号通路的抑制剂,可减少肿瘤球的数量,并抑制 AKT/mTOR 通路。 | |||
T67758 |
Pumecitinib
|
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Pumecitinib 是一种Janus 激酶(JAK)抑制剂。Pumecitinib 显示出抗炎活性。 | |||
T21727 |
Ivermectin B1a
|
SARS-CoV; Parasite | Microbiology/Virology |
Ivermectin B1a 是 Avermectin B1a 的一种衍生物,是 Ivermectin 的主要成分。Ivermectin 是广谱的抗寄生虫剂。Ivermectin 也是抗 SARS-CoV-2/COVID-19 的候选药物。 | |||
T7560 |
Pivmecillinam hydrochloride
匹美西林盐酸盐,FL-1039 hydrochloride,盐酸匹美西林 |
Antibacterial; Antibiotic | Microbiology/Virology |
Pivmecillinam hydrochloride (FL-1039 hydrochloride) 是Mecillinam 的口服活性前药,是一种广谱青霉素抗生素,对革兰氏阴性菌有活性,可用作氨苄青霉素。 | |||
T5836 |
Eprinomectin
依普菌素,MK-397 |
Parasite | Microbiology/Virology |
Eprinomectin (MK-397) 是一种阿维菌素,具有驱虫,杀虫杀螨活性。 | |||
T40652 |
Meclizine
Meclozine |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Meclizine (Meclozine) (Meclozine)具有抗组胺作用,可可逆地抑制组胺与H1受体的相互作用。Meclizine 是哌嗪类H1拮抗剂的一个成员。Meclizine 是一种有效的抗运动病剂。Meclizine 可通过血脑屏障。Meclizine 是小鼠组成型雄烷受体(CAR)的激动剂配体,也是人CAR 的反向激动剂。Meclizine 可用于polyQ 毒性疾病的研究,如亨廷顿病。 | |||
T1110 |
Meclizine dihydrochloride
Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪 |
Apoptosis; Histamine Receptor | Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Meclizine dihydrochloride (NSC28728) 是一种组胺 H1 拮抗剂,用于治疗妊娠期间的晕动病、眩晕和恶心以及放射病。它是小鼠组成型雄甾烷受体激动剂,是人 CAR 的反向激动剂。它可透过血脑屏障,可用于多聚谷氨酰胺毒性障碍方面的研究。 | |||
T2648 |
Pimecrolimus
SDZ-ASM 981,ASM 981,吡美莫司 |
Others | Others |
Pimecrolimus (SDZ-ASM 981) 是一种免疫亲和素配体,能与胞质受体特异性的结合。 | |||
T21369 |
Mecillinam
Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX |
Antibacterial | Microbiology/Virology |
Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。 | |||
T6801 |
CeMMEC13
|
Carboxypeptidase; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome |
CeMMEC13 是一种异喹啉酮,可选择性抑制 TAF1 的第二个溴结构域,IC50为 2.1 μM。 | |||
T26726 |
AzddMeC
CS-92,Azidodideoxymethylcytidine,Az-Dcme |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
AzddMeC (Az-Dcme) 是一种具有口服活性、高效性和选择性的 HIV-1 逆转录酶和 HIV-1 复制抑制剂,具有抗逆转录病毒活性。AzddMeC 可用于研究 HIV-1 感染。 | |||
T22489 |
2'-MeCCPA
2-Chloro-N-cyclopentyl-2′-C-methyladenosine |
HCV Protease; Adenosine Receptor | GPCR/G Protein; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
2'-MeCCPA 是一种具有有效性和高选择性的 A1 腺苷受体 (A1AR) 激动剂,对 AR 的 K 值为 1.8 nM。2'-MeCCPA 抑制毛喉素刺激的腺苷酸环化酶活性,IC值为13.1 nM。2'-MeCCPA 具有镇痛活性,可用于研究 HCV 。 | |||
T16034 |
Meclinertant
SR 48692 |
Others | Others |
Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in human colon carcinoma (HT-29) cell | |||
T4345 |
CeMMEC1
CeMMEC1 HCl |
Epigenetic Reader Domain; Carboxypeptidase; DNA/RNA Synthesis | Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
CeMMEC1 是一种 BRD4 抑制剂,对 TAF1 有很好的亲和力,IC50为0.9 μM。 | |||
T4997 |
Umeclidinium bromide
芜地溴铵,GSK573719A |
AChR | Neuroscience |
Umeclidinium bromide (GSK573719A) 是mAChR 拮抗剂,作用于克隆的人 M1-M5 mAChRs,Ki 为 0.05 到 0.16 nM。 | |||
T2141 |
Mecamylamine hydrochloride
盐酸美加明,Inversine,Mevasin |
AChR | Neuroscience |
Mecamylamine hydrochloride (Mevasin) 是一种易穿过血脑屏障的烟碱拮抗剂,用作高血压的神经节阻滞剂,具有抗神经疾病作用。 | |||
T0013 |
Mecarbinate
优多降,Dimecarbine,Dimecarbin,美卡比酯 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Mecarbinate (Dimecarbin) 是抗 HCV 试剂,也是中间体。 | |||
T1401 |
Meclofenoxate hydrochloride
Meclofenoxate (Centrophenoxine) HCl,Lucidril,盐酸甲氯芬酯,Cerutil,盐酸甲氯酚酯,Meclofenoxate HCl |
Lipoxygenase; COX; AChR; iGluR | Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Meclofenoxate hydrochloride (Lucidril) 是二甲基氨基乙醇和对氯苯氧乙酸的酯,有刺激记忆和提高认知的活性。 | |||
T0260 |
Meclofenamic acid sodium
Meclofenamate Sodium,Movens,Meclomen,甲氯灭酸钠,Meclonax |
Gap Junction Protein; COX | Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience |
Meclofenamic acid sodium (Movens) 是一种非甾体抗炎药,可用于治疗关节炎 、缓解疼痛、痛经和严重月经失血。它是一种非选择性的缝隙连接阻断剂,是一种高选择性的脂肪和肥胖相关酶抑制剂。 | |||
T7605 |
Avermectin B1a
阿维菌素 B1a,Abamectin B1a,Avamectin B1a |
Antibiotic; Parasite | Microbiology/Virology |
Avermectin B1a 是能够使线虫瘫痪的一种抗寄生虫剂。 | |||
T15212 |
Emamectin Benzoate
MK-244,甲胺基阿维菌素苯甲酸盐 |
Apoptosis; Reactive Oxygen Species; GABA Receptor; Parasite | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB |
Emamectin Benzoate (MK-244) 是口服有效的神经系统毒物,其通过结合昆虫中的 GABA 受体发挥作用。它是阿维菌素的半合成衍生物之一,具有广谱的杀虫和杀螨活性。它诱导ROS 介导的 DNA 损伤和细胞凋亡。 | |||
T7213 |
Demecarium bromide
地美溴铵,BC-48 |
AChE | Neuroscience |
Demecarium bromide (BC-48) 是一种有效的cholinesterase 抑制剂,Kiapp=0.15 μM,它可用研究于青光眼。 | |||
T11990 |
Meclofenamic acid
甲氯芬那酸,Meclofenamate |
Others; Gap Junction Protein | Cytoskeletal Signaling; Others |
Meclofenamic acid (Meclofenamate) 是一种非特异性 gap-junction 阻滞剂和特异性脂肪量和肥胖相关 (FTO) 酶抑制剂。 Meclofenamic acid 具有抗炎活性。 | |||
T0260L |
Meclofenamate sodium hydrate
INF 4668,CI583,CI-583,INF-4668,CI 583,INF4668 |
||
Meclofenamate sodium is a potent non-steroidal anti-inflammatory agent, which can specifically inhibit chemokine-induced human polymorphonuclear leukocyte function: chemotaxis, degranulation, and superoxide anion free radical production. | |||
T70250 |
Demeclocycline calcium
|
||
Demeclocycline calcium is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis. | |||
T20632 |
Mecoprop
Mepro,Morogal,Mecprop,Methoxone,Mecoturf |
||
Mecoprop is an herbicide used to control broadleaf weeds. | |||
T24442 |
Mecrylate
|
||
Mecrylate polymerizes in contact with moisture. It is used as a tissue adhesive. It also has higher homologs have hemostatic and antibacterial properties. | |||
T38512 |
2,3-Dehydro-3,4-dihydro ivermectin
|
||
2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes ( IC 50 s=13.8 and 3.6 μM, respectively) without inducing cytotoxicity to macrophages ( IC 50 = 65.5 μM). | |||
TP2430 |
Cucumechinoside D
|
||
Cucumechinoside D is a natural bioactive chemical. | |||
T39715 |
MeCY5-NHS ester potassium
Sulfo-Cyanine5 NHS ester potassium,MeCY5-NHS ester potassium |
||
MeCY5-NHS ester (potassium) is a reactive dye designed for labeling proteins and nucleic acids. | |||
T22874 |
Ivermectin B1a-d2
|
Others | Others |
Deuterated ivermectin B1a | |||
T31893 |
Furmecyclox
BAS 389,BAS-389,BAS 389F,BAS389,GUS 215 |
||
Furmecyclox is a biochemical. | |||
T71873 |
Temechine hydrobromide
|
||
Temechine hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors. | |||
T14082 |
AB-MECA
|
Others | Others |
AB-MECA is a high affinity A3 adenosine receptor agonist. It has high affinity for recombinant A1 and A3 receptors. | |||
T70311 |
Demecarium Free Base
|
||
Demecarium Free Base is a quaternary ammonium compound that serves as a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically, demecarium inactivates both pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown and increasing acetylcholine activity. | |||
T24690 |
Pyrromecaine HCl
Bumecaine hydrochloride,Pyrromecaine |
||
Pyrromecaine is a local anesthetic used for surface anesthesia. Pyromecaine has a wide spectrum of antiarrhythmic action, exerts a favorable effect on the contractility of the left ventricle, and on the myocardial blood flow following the ligation of the | |||
T24641 |
Pimeclone hydrochloride
NU852,NSC 18727,NU 582,Pimeclone HCl,NU-582 |
||
Pimeclone hydrochloride is a psychostimulant or a respiratory stimulant drug. | |||
T31815 |
Flumecinol
Zyxorin |
||
Flumecinol is a hepatic enzyme (cytochrome P-450 monooxygenases) inducer. | |||
T24881 |
Thymectacin
NB 1011,NB-1011,NB1011 |
||
Thymectacin is a small molecule phosphoramidite derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine with potential antineoplastic activity. | |||
T35756 |
Avermectin B1a monosaccharide
|
||
Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a . It is lethal to C. elegans with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a monosaccharide also stimulates conductance in isolated shore crab muscle. | |||
T35733 |
Doramectin aglycone
|
||
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone. | |||
T125077 |
Mecambridine
|
||
Mecambridine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125077。 | |||
T32016 |
Guamecycline
Guamecyclinum,Guameciclina |
||
Guamecycline is a biochemical. | |||
T35755 |
Avermectin B1a aglycone
|
||
Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance. | |||
T64965 | Avermectin | ||
Avermectin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64965。 | |||
T31401 |
S-(+)-Mecamylamine hydrochloride
NIH-11008,TC-5214,Dexmecamylamine HCl,NIH11008,TC 5214,NIH 11008,TC5214 |
||
Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0969 |
Doramectin
Dectomax,Cyclohexylavermectin B1,多拉菌素 |
Others; Antibiotic; Parasite | Microbiology/Virology; Others |
Doramectin (Dectomax) 是 Ivermectin 的衍生物。它是一种抗寄生虫抗生素。它具有在 NMRI 小鼠感染模型中抗曼氏链球菌作用。 | |||
T0956 |
Avermectin B1
Avermectin B1a-Avermectin B1b mixt.,Abamectin,阿维菌素 |
Antibiotic; Parasite; Autophagy | Autophagy; Microbiology/Virology |
Avermectin B1 是驱虫杀虫剂。 | |||
T37508 |
Meconin
|
Endogenous Metabolite | Metabolism |
Meconine 是一种人内源性代谢产物。 | |||
TL0015 |
Pyromeconic acid
3-羟基-4氢-吡喃-4-酮,3-hydroxy-4H-pyran-4-one |
Anti-infection | Microbiology/Virology |
Pyromeconic acid (3-hydroxy-4H-pyran-4-one) 及其衍生物是核酸内切酶的有效抑制剂 | |||
T1400 |
Demeclocycline hydrochloride
地美环素,Declomycin,Clortetrin,盐酸地美环素,Detravis,Demeclocycline HCl |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Demeclocycline hydrochloride (Declomycin) 是四环素类抗生素,可治疗粉刺,莱姆病和支气管炎。 | |||
T0281 |
Meclocycline sulfosalicylate salt
磺基水杨酸甲氯环素,Meclutin,Mecloderm,甲环素磺基水杨酸盐,Meclan Cream |
Antibacterial; Antibiotic | Microbiology/Virology |
Meclocycline sulfosalicylate salt (Mecloderm) 是一种具有广谱抗菌活性的四环素抗生素,可预防皮肤细菌感染。 | |||
T1131 |
Ivermectin
MK-933,伊维菌素 |
Mitophagy; GluCls; P2X Receptor; SARS-CoV; HIV Protease; Antibiotic; Parasite; Autophagy; HSV | Autophagy; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome |
Ivermectin (MK-933) 是谷氨酸门控氯离子通道激活剂,具有抗寄生虫活性。它特异性抑制Impα/β1 介导的核导入,还抑制牛疱疹病毒 1 复制并抑制BoHV-1DNA 聚合酶的核输入。它具有很强的抗病毒活性。它也是P2X4和 α7nAChRs 的正异构效应物。 | |||
T35743 |
Ivermectin B1a aglycone
|
||
Ivermectin B1a aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity. | |||
T40929 |
Mechercharmycin A
|
||
Mechercharmycin A, a cytotoxic compound, was isolated from Thermoactinomyces sp. YM3-251, a marine source. It demonstrates potent antitumor activity. | |||
T11842 |
Levomecol
|
Others | Others |
Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthesis by blocking peptidyl transferase. | |||
T35752 |
Xanthoquinodin A1
Xanthoquinodin A1 |
||
Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value of 0.02 μg/ml.1Xanthoquinodin A1 is active againstB. subtilis,M. luteus,S. aureus,A. laidlawii, andB. fragilisin a disc assay when used at a concentration of 1 mg/ml. It is also active againstB. cereus(MIC = 0.44 μM).2Xanthoquinodin A1 is cytotoxic to KB, MCF-7, and NCI H187 cance... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03728 |
CCL28 Protein, Human, Recombinant (His)
MEC,SCYA28,chemokine (C-C motif) ligand 28,CCK1 |
Human | E. coli |
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues an... | |||
TMPJ-00019 |
CCL28 Protein, Human, Recombinant
Small-Inducible Cytokine A28,Protein CCK1,CCL28,SCYA28,C-C M... |
Human | E. coli |
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expresse... | |||
TMPJ-00460 |
MECR Protein, Human, Recombinant (His)
Nuclear Receptor-Binding Factor 1,HsNrbf-1NRBF-1,MEC |
Human | HEK293 Cells |
Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain... | |||
TMPH-03521 |
MecA Protein, S. aureus, Recombinant (His & SUMO)
|
Staphylococcus aureus | E. coli |
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P60186. | |||
TMPH-03035 |
M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)
|
Myrmecia pilosula | Baculovirus Insect Cells |
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplant... | |||
TMPJ-00998 |
MECP2 Protein, Human, Recombinant (His)
Methyl-CpG-binding protein 2,MeCp-2 protein,MEC... |
Human | HEK293 Cells |
The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may ... | |||
TMPH-02254 |
Trypsin-1 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates. |