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Search Results for " duvelisib hydrochloride(1261590-48-0 free base) "
Targets Recommended: PI3K

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Cat. No. Product Name Target Signaling Pathways
T11129L Duvelisib (R enantiomer) hydrochloride

IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl

PI3K PI3K/Akt/mTOR signaling
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) 是 PI3K 抑制剂。Duvelisib (R enantiomer) hydrochloride 是 Duvelisib 的活性较低的对映体。
T1988 Duvelisib

INK1197,IPI-145,度维利塞

PI3K PI3K/Akt/mTOR signaling
Duvelisib (INK1197) 是 p100δ的选择性抑制剂,能够作用于 p110δ (IC50:2.5 nM)、p110γ (IC50:27.4 nM)、p110β (IC50:85 nM) 和 p110α (IC50:1602 nM)。
T11129 Duvelisib (R enantiomer)

Duvelisib R enantiomer,IPI-145 R enantiomer,INK1197 R enantiomer

PI3K PI3K/Akt/mTOR signaling
Duvelisib R enantiomer (IPI-145 R enantiomer) 是一种 Duvelisib 的对映异构体,活性较低。 它是一种 PI3K 抑制剂。
T70802 Duvelisib hydrate

Others Others
Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike oth...

化合物

Duvelisib (R enantiomer) hydrochloride
Cat.No: T11129L
Synonym: IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl
Target: PI3K
Duvelisib
Cat.No: T1988
Synonym: INK1197,IPI-145,度维利塞
Target: PI3K
Duvelisib (R enantiomer)
Cat.No: T11129
Synonym: Duvelisib R enantiomer,IPI-145 R enantiomer,INK1197 R enantiomer
Target: PI3K
Duvelisib hydrate
Cat.No: T70802
Synonym:
Target: Others
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