10000
100
3
1
| Cat. No. | Product Name | Form | Specificity Of Inhibition |
|---|---|---|---|
| C0005 |
Cell Counting Kit-8 (CCK-8)
Cell Counting Kit-8 (CCK-8) |
Solution in bottle | |
| C0003 |
Phosphatase Inhibitor Cocktail II (100× DMSO)
磷酸酶抑制剂 Cocktail II |
Solution (100× in DMSO) | Alkaline phosphatases, Ser/Thr phosphatases, <em><em>Acid</em></em> and PP1 and PP2A |
| C0002 |
Phosphatase Inhibitor Cocktail I (100× ddH2O)
磷酸酶抑制剂 Cocktail I |
Solution (100× in ddH2O) | <em><em>Acid</em></em> Phosphatase, Alkaline phosphatase, PTPs, ATPases |
| Cat. No. | Product Name | ||
|---|---|---|---|
| EC3000 | TargetMol® 24 道磁力架 | ||
| 强力钕磁铁部件，吸附效率高，可兼容所有磁珠。助力核酸分离、蛋白纯化、细胞分选！可同时分离 24管样品，节省实验时间；操作简单，架身美观小巧，价格优惠。 | |||
| Cat. No. | Product Name | Target | Signaling Pathways |
|---|---|---|---|
| T9956 | VK-28 | Mitochondrial Metabolism; Lipid | Metabolism |
| VK-28 是一种具有神经保护作用的脑渗透性铁螯合剂。 VK-28 抑制基础以及铁诱导的线粒体脂质过氧化。 | |||
| T17258 | WRG-28 | Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
| WRG-28 是一种选择性的、细胞外作用的DDR2变构抑制剂 (IC50:230 nM)。它通过受体的变构调节特异地抑制受体-配体相互作用。它通过靶向 DDR2 抑制肿瘤侵袭和迁移，基质的肿瘤支持作用，能够抑制肺中的转移性乳腺肿瘤细胞定植。 | |||
| T5689 | 20-DEOXYINGENOL | Others; Autophagy | Autophagy; Others |
| 20-Deoxyingenol 是从甘遂的根中分离出的一种二萜类天然产物。它可通过促进体外转录因子 EB 的核易位来促进自噬和溶酶体生物发生，可研究骨关节炎。 | |||
| TP2495 |
Tripeptide-29 Acetate
Tripeptide-29 Acetate(2239-67-0 Free base) |
Others | Others |
| Tripeptide-29 Acetate 是一种研究化学品，可改善皮肤状况并有助于减少细纹和皱纹。 | |||
| TP1863L | Glucagon (19-29), human acetate | Glucagon Receptor | GPCR/G Protein |
| Glucagon (19-29), human acetate 是一种从胰高血糖素加工而来的 COOH 末端片段，是一种有效的胰岛素分泌抑制剂。 | |||
| TP2124L |
Somatostatin 1-28 acetate
Somatostatin 1-28 acetate(74315-46-1 Free base) |
Somatostatin | GPCR/G Protein |
| Somatostatin 1-28 acetate 在人源血浆中循环。 血浆中约 46% 的总生长抑素样免疫反应性是由于 Somatostatin 1-28 acetate 所致。 | |||
| T4751 |
(2R,3R)-Butane-2,3-diol
(2R,3R)-(-)-2,3-丁二醇; levo-2,3-Butanediol; (2R,3R)-(-)-2,3-Butanediol |
Others; Endogenous Metabolite | Others; Metabolism |
| (2R,3R)-(-)-2,3-Butanediol 是内源性代谢产物的一种。 | |||
| TP2316 | Myristoyl Hexapeptide-23 Acetate | Others | Others |
| Anti acne. | |||
| TP1263 |
Fz7-21
(Ac)-LPSDDLEFWCHVMY-NH2 |
Wnt/beta-catenin | Cytoskeletal Signaling; Stem Cells |
| Fz7-21 是一种 Frizzled 7 (FZD 7) 受体的肽抑制剂，能够选择性的与FZD7 CRD亚类结合。它还阻断了WNT3A介导的β-catenin在小鼠L细胞中的稳定作用。它对外源性WNT3A刺激和转染WNT3A或WNT1的HEK293细胞Wnt/β-catenin信号传导有损伤。 | |||
| T67728 | α-Glucosidase-IN-23 | Metabolism | |
| α-Glucosidase-IN-23 是具有口服活性的 α-Glucosidase 抑制剂。α-Glucosidase-IN-23 通过抑制 a-glucosidase 降低血糖 (IC50= 4.48 μM)。α-Glucosidase-IN-23 可用于糖尿病的研究。 | |||
| T5500 | DORA-22 | OX Receptor | Neuroscience; GPCR/G Protein |
| DORA-22 是一种双食欲素受体拮抗剂，可改善轻度压力引起的失眠，对记忆的影响最小。 | |||
| T4S0999 |
(2S)-Isoxanthohumol
(2S)-异黄腐酚; 异黄腐醇; Isoxanthohumol |
Virus Protease; HSV | Microbiology/Virology |
| Isoxanthohumol 是一种由啤酒花原异戊烯基二氢黄酮 Isoxanthohumol 的微生物转化代谢物。 | |||
| TP1246L |
ACTH (22-39) acetate
ACTH (22-39) acetate (37548-29-1 Free base) |
Others | Others |
| ACTH (22-39) acetate 是促肾上腺皮质激素 (ACTH) 的片段，在 N 末端的第 3 位和第 15 位含有两个脯氨酸残基。 | |||
| TN2802 | 20-O-Glucoginsenoside Rf | Others | Others |
| 20-O-Glucoginsenoside Rf 是从人参 Panax ginseng C. A. Mey 中提取的天然产物。 | |||
| T37890L |
GLP-1(28-36)amide acetate
GLP-1(28-36)amide acetate(1225021-13-5 Free base) |
Antioxidant; Glucagon Receptor | GPCR/G Protein; oxidation-reduction |
| GLP-1(28-36)amide acetate 抑制线粒体通透性转变，具有抗氧化、抗糖尿病和心脏保护活性。 | |||
| TP2083L |
Ac9-25 acetate
Ac9-25 acetate(284040-76-2 free base) |
Others | Others |
| Ac9-25 acetate 通过 FPR 激活中性粒细胞还原的烟酰胺腺嘌呤二核苷酸磷酸氧化酶。 | |||
| TP2358 | KRPEP-2D acetate | Raf | MAPK |
| KRPEP-2D acetate was identified as a K-Ras(G12D) selective inhibitory peptide against the G12D mutant of K-Ras, which is a key member of the Ras protein family and an attractive cancer therapeutic target. | |||
| T9812 | Tubulin inhibitor 24 | Microtubule Associated | Cytoskeletal Signaling |
| Tubulin inhibitor 24 是一种 tubulin 抑制剂，可以抑制微管蛋白聚合，以浓度依赖性方式诱导细胞周期停滞在 G2/M 期， 具有抗肿瘤活性且无明显毒性。 | |||
| T9612 | Antibacterial agent 27 | Anti-infection | Microbiology/Virology |
| Antibacterial agent 27 是抗菌化合物，显示出有效的抗念珠菌活性。 | |||
| TP2489 |
Tetrapeptide-21 Acetate
Tetrapeptide-21 Acetate(960608-17-7 Free base) |
Others | Others |
| Tetrapeptide-21 Acetate 是一种新型生物活性纯四肽，具有基于皮肤自身结构的抗衰老特性，可用于护肤配方。 | |||
| TPL0186 | Compound 1769-24-0 | ||
| TP1140L | Neuropeptide Y (29-64), amide, human acetate | Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
| Neuropeptide Y (29-64), amide, human acetate 参与阿尔茨海默病 (AD) 并保护大鼠皮质神经元免受 β-淀粉样蛋白毒性。 | |||
| TQ0099 |
20-O-Acetylingenol-3-angelate
Euphorbia factor Pe1; 巨大戟醇-3-O-当归酸-20-乙酸酯 |
Others | Others |
| 20-O-Acetylingenol-3-angelate 是一种天然化合物。 | |||
| TP1914L1 |
BAM (8-22) acetate
BAM (8-22) acetate(412961-36-5 free base) |
Others | Others |
| BAM (8-22) acetate 是脑啡肽原 A 的蛋白水解产物。BAM (8-22) acetate 可激活 Mas 相关的 G 蛋白偶联受体 (Mrgprs)、MrgprC11 和 hMrgprX1，并以 Mrgpr 依赖性方式诱导小鼠抓挠。 | |||
| TP1957L | PKI (5-24) Acetate(99534-03-9 free base) | PKA | Tyrosine Kinase/Adaptors |
| PKI (5-24) Acetate is a high affinity PKA inhibitor (Ki = 2.3 nM). | |||
| TP1248L |
ACTH 11-24 acetate(4237-93-8 free base)
Adrenocorticotropic Hormone (11-24) acetate |
Melanocortin Receptor | Neuroscience; GPCR/G Protein |
| ACTH (11-24) acetate is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells. | |||
| TP1214L |
β-Amyloid 15-21 acetate
Beta-Amyloid (15-21) acetate |
Beta Amyloid | Neuroscience |
| β-amyloid (15-21) acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation. | |||
| T21983L |
PKI 14-22 amide, myristoylated Acetate
PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base) |
PKA | Tyrosine Kinase/Adaptors |
| PKI 14-22 amide, myristoylated Acetate 抑制 cAMP 依赖性蛋白激酶 (PKA) 并阻断脊髓给药 8-溴-cAMP 产生的痛觉过敏。 | |||
| T60150 | (1S,2R)-Alicapistat | Cysteine Protease | Proteases/Proteasome |
| (1S,2R)-Alicapistat ((1S,2R)-ABT-957) 是一种具有口服活性的人钙激活中性蛋白酶 (calpains 1和2) 的选择性抑制剂，可能用于阿尔茨海默病 (AD) 的研究。 Alicapistat 可减轻羰基还原的代谢倾向，对calpain 1的IC50为 395 nM。 | |||
| T7566L |
GRGDSPK 2TFA(111119-28-9(free base))
EMD 56574 |
Others | Others |
| GRGDSPK 2TFA(111119-28-9(free base)) 是一种抑制肽，用于 RGD 介导的整合素和细胞外基质分子之间的粘附。 | |||
| TP1430 |
DTP3 TFA (1809784-29-9 free base)
DTP3 TFA |
Others | Others |
| DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. | |||
| T6S2243 |
Alisol A 24-acetate
Alisol A 24-monoacetate; Alisol A monoacetate; 泽泻醇A24-醋酸酯 |
Others | Others |
| Alisol A 24-acetate 是一种天然产物。 | |||
| T5398 |
BMS 599626 2HCl (873837-23-1(HCl))
AC480 dihydrochloride |
HER | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
| BMS-599626 (AC480) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc. | |||
| T39392L |
C-Type Natriuretic Peptide (CNP) (1-22), human acetate
C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base) |
Others | Others |
| C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂，一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。 | |||
| T7616L |
A 779 TFA(159432-28-7 free base)
A 779 3TFA(159432-28-7(free base)) |
RAAS | Endocrinology/Hormones |
| A 779(3TFA) is a potent antagonist of angiotensin-(1-7) receptor | |||
| TP1345 | Kisspeptin-10, human (TFA)(374675-21-5,FREE) | GPR | GPCR/G Protein; Endocrinology/Hormones |
| Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression | |||
| T8832 |
Eledoisin trifluoroacetate (69-25-0 free base)
Eledoisin trifluoroacetate |
Others | Others |
| Eledoisin trifluoroacetate (69-25-0 free base) 是从某些小章鱼（Eledone spp.，Mollusca）的后唾液腺中提取或合成获得的肽。它的作用类似于 P 物质的作用；它是一种有效的血管扩张剂，可增加毛细血管的通透性。 | |||
| TP1033L |
Transdermal Peptide acetate(888486-23-5 free base)
TD 1 (peptide) acetate |
ATPase | Membrane transporter/Ion channel |
| Transdermal Peptide (TD 1 peptide) acetate is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transde | |||
| TP1219 |
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
ANP (1-28), human, porcineANP(1-28) |
||
| Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate cyclase, has been found to protect against reoxygenation-induced hypercontracture in isolated cardiomyocytes by increasing cyclic guanosine monophosphate synthesis; ANP also contribut | |||
| T7680 |
GSNKGAIIGLM(131602-53-4(free base))
BETA-淀粉样蛋白片断25-35; Amyloid beta-peptide(25-35) |
Beta Amyloid | Neuroscience |
| GSNKGAIIGLM(131602-53-4(free base)) 是阿尔茨海默病淀粉样蛋白 β-肽的片段 Aβ(25-35)。 | |||
| T60161 | CP-289 | Complement System | Immunology/Inflammation |
| CP-289是一种有效的C5a受体拮抗剂，IC50为1μM。 | |||
| TP1686L | JAG-1, scrambled TFA(402941-23-5 free base） | Others | Others |
| JAG-1, scrambled TFA(402941-23-5 free base) 是 JAG-1(188-204) 的加扰序列。 | |||
| T60125 | (2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid | Others | Others |
| (2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid是化学合成中间体。 | |||
| TN7074 | (2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid | Antibiotic | Microbiology/Virology |
| (2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid 对克氏锥虫的 EC50 值为 73.5 μM。 | |||
| TP1004L |
Beta-MSH (1-22) (human) acetate
Beta-MSH (1-22) (human) acetate (17908-57-5 Free base); 醋酸Β-促黑激素(人) |
Melanocortin Receptor | Neuroscience; GPCR/G Protein |
| Beta-MSH (1-22) (human) acetate 是一种 22 肽，是一种内源性黑皮质素 4 受体 (MC4-R) 激动剂。 | |||
| TP1687L | CEF20 acetate(153045-21-7 free base) | Others | Others |
| CEF20 acetate is a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503). | |||
| T4248 | T.cruzi Inhibitor (1350920-22-7(free base)) | Antibiotic | Microbiology/Virology |
| T.cruzi Inhibitor (1350920-22-7(free base)) 是一种克氏锥虫抑制剂。 | |||
| TP1386L1 | Mastoparan acetate(72093-21-1 free base) | Others | Others |
| Mastoparan acetate(72093-21-1 free base) 是一种来自黄蜂毒液的肽毒素。它的化学结构为 Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2。 | |||
| T35351L |
GO-203 acetate
GO-203 acetate (1222186-26-6 Free base) |
Others | Others |
| GO-203 acetate 是一种有效的 MUC1-C 癌蛋白抑制剂。 GO-203 acetate 对细胞内蛋白质表现出抗癌活性。 | |||
| T13616 |
Cis-9,10-Epoxystearic acid
cis-9,10-Epoxystearic acid; cis-9,10-Epoxyoctadecanoic acid |
Endogenous Metabolite | Metabolism |
| cis-9,10-Epoxystearic acid 是来自人血液和尿液的内源性成分。它可以通过油酸和非酶环氧化反应从油酸中制备。 | |||
沪公网安备 31010602006700号
