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  • 抑制剂&激动剂
    42
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    2
    TargetMol | Recombinant_Protein
  • 染料试剂
    3
    TargetMol | Dye_Reagents
  • 天然产物
    11
    TargetMol | Natural_Products
  • 同位素
    1
    TargetMol | Isotope_Products
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    2
    TargetMol | Antibody_Products
  • 分子与细胞研究
    7
    TargetMol | Inhibitors_Agonists
  • PE(10:0/10:0)
    T66959
    PE(10:0 10:0) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T66959。
    • ¥ 2098
    5日内发货
    规格
    数量
  • C10 Ceramide (d18:1/10:0)
    Ceramide (d18:1 10:0), N-decanoyl-D-erythro-Sphingosine, C10 Ceramide, Cer(d18:1 10:0)
    T85193111122-57-7
    C10 Ceramide (d18:1 10:0) 是一种脂质分子,可用于生命科学相关研究,其 CAS 号为 111122-57-7。
    • 待询
    8-10周
    规格
    数量
  • 16:0-10 Doxyl PC
    TCL-00120188004-25-3
    16:0-10 Doxyl PC 一种在生化反应中使用的试剂。
    • 待询
    5日内发货
    规格
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  • 1,2-Didecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
    TCL-00291322647-25-6
    1,2-Didecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (10:0 PG) sodium 一种在生化反应中使用的试剂。
    • 待询
    5日内发货
    规格
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  • 18:0 (9,10dibromo) PC
    TCL-00119217075-01-9
    18:0 (9,10dibromo) PC 一种在生化反应中使用的试剂。
    • 待询
    5日内发货
    规格
    数量
  • Dextran sulfate sodium salt (MW 6500-10000)
    9011-18-1
    TXB-00495
    Dextran sulfate sodium salt (MW 6500-10000) (DSS (MW 6500-10000)) 是一种带负电荷的硫酸化多糖,具有抗病毒、抗菌、抗炎、抗纤维化和促进伤口愈合的特性。它可作为细胞培养基中的添加剂以防止细胞聚集,还可作为化妆品中的凝胶形成剂。
    • 待询
    5日内发货
    规格
    数量
  • Polyvinyl alcohol (Mw 9000-10000)
    9002-89-5
    TYD-01473
    Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) 又称为 PVA,是一种水溶性乙烯基聚合物,能作为非离子表面活性剂。Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) 也可用作可生物降解的聚合物,广泛应用于粘合剂、涂料、纺织品、陶瓷和化妆品。
    • 待询
    5日内发货
    规格
    数量
  • Theaflavin 3,3′-digallate
    茶黄素-3,3'-双没食子酸, Theaflavin 3,3′-di-O-gallate, Theaflavin 3, TFDG
    T542930462-35-2
    Theaflavin 3,3'-digallate 是一种寨卡病毒蛋白酶抑制剂,IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制,可抑制 gp41 和 NS2B-3 蛋白酶的活性,并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚,有抗肿瘤作用。
    • ¥ 686
    In stock
    规格
    数量
  • COR659
    T36520544450-68-2
    COR659 是一种有效的 GABAB 的阳性变构调节剂。COR659具有缓解大鼠对酒精和巧克力成瘾的作用。
    • ¥ 343
    In stock
    规格
    数量
    TargetMol | Inhibitor Sale
  • Pipernonaline
    T12400088660-10-0
    Pipernonaline 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124000,CAS号为 88660-10-0。
    • 待询
    规格
    数量
  • 7-Acetoxy-15-methoxy-10-O-methyldihydrobotrydial
    T125441196796-12-0
    7-Acetoxy-15-methoxy-10-O-methyldihydrobotrydial 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125441,CAS号为 196796-12-0。
    • 待询
    规格
    数量
  • ER degrader 10
    T2047753035311-43-1
    ER degrader 10 (Compound 51) 是一种口服有效的雌激素受体 (ER) 选择性降解剂和拮抗剂,其DC50为0.43 nM,IC50为0.56 nM。它能够抑制ER阳性细胞的增殖,IC50范围在0至15 nM。对hERG通道的抑制作用较弱,IC50大于40 μM。该化合物具有良好的血脑屏障通透性,其脑 血浆比 (Kp) 为3.05。在小鼠模型中,ER degrader 10 展示了抗肿瘤活性。
    • 待询
    10-14周
    规格
    数量
  • Janthitrem F
    Janthitrem E monoacetate
    T3226190986-52-0
    Janthitrem f, as a 10-0-acetyljanthitrem e or janthitrem e monoacetate, is a type ofnaphthopyran. Janthitrem F is prepared by Penicillium janthinellum. Tremorgenic mycotoxi.
    • ¥ 10600
    待询
    规格
    数量
  • JB 1-0
    T3227778617-10-4
    JB 1-0 is a bioactive chemical.
    • ¥ 10600
    待询
    规格
    数量
  • O-7460
    T357861572051-31-0
    In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol by attacking DAG at the sn-1 position. O-7460 is a selective inhibitor of 2-AG biosynthesis via DAGLα (IC50 = 690 nM). It demonstrates much weaker inhibition towards human monoacylglycerol lipase and rat brain fatty acid amide hydrolase (IC50s > 10 μM) and does not bind to CB1 or CB2 cannabinoid receptors (Kis > 10 μM). At 0-12 mg kg, i.p. in mice, O-7460 was reported to dose-dependently inhibit high-fat diet intake and reduce body weight.
    • 待估
    35日内发货
    规格
    数量
  • CAY10744
    T361952375613-31-1
    CAY10744 is a topoisomerase II-α poison.1 It inhibits topoisomerase II-α by 78.9% when used at a concentration of 20 μM. CAY10744 is selective for topoisomerase II-α over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 μM. It inhibits proliferation of HCT15 colon, T47D breast, DU145 prostate, and HeLa cervical cancer cells (IC50s = 0.014, 0.00267, 0.072, and 2.46 μM, respectively). CAY10744 induces apoptosis in T47D cells when used at concentrations of 10 and 30 μM. CAY10744 (12 mg/kg per day) reduces tumor growth in an MDA-MB-231 orthotopic mouse model of breast cancer. |1. Kadayat, T.M., Park, S., Shrestha, A., et al. Discovery and biological evaluations of halogenated 2,4-diphenyl indeno[1,2-b]pyridinol derivatives as potent topoisomerase IIa-targeted chemotherapeutic agents for breast cancer. J. Med. Chem. 62, 8194-8234 (2019).
    • 待估
    35日内发货
    规格
    数量
  • Ganglioside GD1b Mixture (sodium salt)
    Ganglioside GD1b Mixture (sodium salt)
    T3686119553-76-5
    Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside GD1b mixture contains ganglioside GD1b molecular species with C18:1 and C20:1 fatty acyl chains.
    • 待估
    35日内发货
    规格
    数量
  • JC-171
    T381062112809-98-8
    JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages[1]. JC-171 (0-100 μM) blocks NLRP3 inflammasome activation and IL-1β production in primary macrophages dose dependently[1]. Cell Viability Assay[1] Cell Line: J774A.1 murine macrophage cells JC-171 treatment delays the progression and reduces the severity of experimental autoimmune encephalomyelitis (EAE) in mouse[1]. Animal Model: Mice immunized subcutaneously with 200 μg Myelin oligodendrocyte glycoprotein (MOG) 35-55 peptide emulsified in Complete Freund's Adjuvant (CFA) on day 0 followed by injection of 200 ng of pertussis toxin. [1]. Chunqing Guo, et al. Development and Characterization of a Hydroxyl-Sulfonamide Analogue, 5-Chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide, as a Novel NLRP3 Inflammasome Inhibitor for Potential Treatment of Multiple Sclerosis. ACS Chem Neurosci. 2017 Oct 18;8(10):2194-2201.
    • ¥ 2130
    5日内发货
    规格
    数量
  • Mpro inhibitor N3 hemihydrate
    T38174
    Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS-CoV and MERS-CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV-229E, FIPV, and MHV-A59 with individual IC50 of 4.0 μM, 8.8 μM, and 2.7 μM, respectively[1][2]. Mpro inhibitor N3 hemihydrate (0-0.64 μM) is able to penetrate cells to inhibit the replication of IBV viruses, probably at the beginning of infection in embryos[3]. [1]. Jin Z, et al. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors. Nature. 2020;582(7811):289-293.[2]. Yang H, et al. Design of wide-spectrum inhibitors targeting coronavirus main proteases [published correction appears in PLoS Biol. 2005 Nov;3(11):e428]. PLoS Biol. 2005;3(10):e324.[3]. Wang F, et al. Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design. Sci Rep. 2016;6:22677. Published 2016 Mar 7.
    • ¥ 1093
    待询
    规格
    数量
  • HDAC1/2-IN-3
    HDAC1 2-IN-3
    T395672121516-17-2
    HDAC1/2-IN-3 is an inhibitor of both HDAC1 and HDAC2, demonstrating IC50 values of 0-5 nM and 5-10 nM, respectively.
    • ¥ 10600
    6-8周
    规格
    数量
  • Tricaprin
    三癸酸甘油酯, 甘油三癸酸酯, Tridecanoin, TG(10:0 10:0 10:0), Glyceryl tridecanoate, Glycerol Tridecanoate, Glycerol tricaprate
    T5227621-71-6
    Glycerol Tridecanoate 是癸酸的一种口服具有活性前体 (DA precursor),能够被水解为癸酸。它是中链甘油三酸酯 (MCT) 的主要成分,具有抗雄激素和抗高血糖特性。 它能够用做食品,药品,化妆品中的添加剂。
    • ¥ 118
    In stock
    规格
    数量
  • N-Benzyloxycarbonyl-tert-leucine
    T6609862965-10-0
    N-Benzyloxycarbonyl-tert-leucine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66098,CAS号为 62965-10-0。
    • 待询
    5日内发货
    规格
    数量
  • N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
    T66148289042-10-0
    N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66148,CAS号为 289042-10-0。
    • 待询
    5日内发货
    规格
    数量