血管内皮生长因子受体 (Vascular Endothelial Growth Factor Receptors, VEGFRs) 是血管内皮生长因子(Vascular Endothelial Growth Factor ,VEGF)的受体。VEGFR有三种主要亚型,编号为1、2和3。根据选择性剪接,它们可能是膜结合的 (mbVEGFR) 或可溶的 (sVEGFR)。 VEGFR的细胞外部分由 7 个免疫球蛋白样结构域、一个跨膜区域和一个包含分裂酪氨酸激酶结构域的细胞内部分组成。VEGFR-2 似乎介导了几乎所有已知的细胞对 VEGF 的反应。VEGFR-1 的功能尚不明确,尽管它被认为可以调节 VEGFR-2 信号传导。VEGFR-1 的另一个功能是充当虚拟/诱饵受体,将 VEGF 从 VEGFR-2 结合中隔离出来。VEGFR-1 (sFlt1) 的可变剪接形式不是膜结合蛋白,而是分泌的,主要用作诱饵。VEGFR-3 介导淋巴管生成以响应 VEGF-C 和 VEGF-D。VEGFR抑制剂用于治疗癌症。
Cat. No. | Product Name / Synonyms | Species | Expression System |
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TMPJ-00414 | VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated
|
Human | Human Cells |
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in ... | |||
TMPJ-00593 | VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)
|
Human | Human Cells |
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in ... | |||
TMPK-00445 | VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosi... | |||
TMPK-00446 | VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated
VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated
|
Human | HEK293 |
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosi... | |||
TMPK-00450 | VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class... | |||
TMPK-00451 | VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class... | |||
TMPK-00454 | VEGFR2/KDR Protein, Human, Recombinant (His & Avi)
VEGFR2/KDR Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, t... | |||
TMPK-00645 | VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
|
Rhesus macaque | HEK293 |
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, t... | |||
TMPY-00119 | FLT1 Protein, Human, Recombinant (hFc)
FLT1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor F... | |||
TMPY-01044 | VEGFR2/KDR Protein, Human, Recombinant (hFc)
VEGFR2/KDR Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-01069 | VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are recept... | |||
TMPY-01937 | VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are recept... | |||
TMPY-02108 | FLT1 Protein, Human, Recombinant (aa 1-756, His)
FLT1 Protein, Human, Recombinant (aa 1-756, His)
|
Human | HEK293 |
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor F... | |||
TMPY-02678 | VEGFR2/KDR Protein, Rat, Recombinant (His)
VEGFR2/KDR Protein, Rat, Recombinant (His)
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Rat | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-02736 | VEGFR2/KDR Protein, Mouse, Recombinant (His)
VEGFR2/KDR Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-02858 | VEGFR2/KDR Protein, Mouse, Recombinant (hFc)
VEGFR2/KDR Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-03202 | VEGFR2/KDR Protein, Rat, Recombinant (hFc)
VEGFR2/KDR Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-03299 | FLT1 Protein, Rat, Recombinant (His)
FLT1 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor F... | |||
TMPY-04530 | VEGFR2/KDR Protein, Human, Recombinant (His & GST)
VEGFR2/KDR Protein, Human, Recombinant (His & GST)
|
Human | Baculovirus-Insect Cells |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04794 | VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... |