桑属

1-Deoxynojirimycin (Moranoline) 是一种口服具有活性的 α-葡萄糖苷酶抑制剂。它具有降血糖、减肥和抗病毒的活性。它抑制餐后血糖，预防糖尿病。

Kuwanon E 是从桑树中提取得到的黄酮类化合物，具有潜在的抗炎活性，抑制TNF-α 和 IL-1β 分泌，抑制 LPS 刺激的巨噬细胞中 NF-κB 核易位。

Kuwanon U (4'-methoxykuwanon E) 是一种来自桑树的化合物，是一种胆碱酯酶抑制剂，具有抗菌活性，抑制乙酰胆碱酯酶 （AChE） 和丁酰胆碱酯酶 （BChE），通过阻止 ATP 结合在 SERCA1 的胞质区域发挥抑制作用，可用于研究糖尿病和细菌感染。

Moracin M 是桑白皮中的一种酚类成分，有效的磷酸二酯酶 4 (PDE4) 抑制剂，对于 PDE4D2，PDE4B2，PDE5A1 和 PDE9A2 的 IC50 分别为 2.9 μM，4.5 μM，> 40 μM 和 > 100 μM。Moracin M 具有抗炎活性。

Quercetin-3-O-glucose-6''-acetate (6 -O-Acetylisoquercitrin) 是 NADPH 氧化酶的抑制剂。 Quercetin-3-O-glucose-6''-acetate 具有抗氧化活性。

Mulberrofuran C(桑葚呋喃 C)是存在于Morus alba中的苯并呋喃，对Aβ₁₋₄₂自聚集、tau蛋白聚集、AChE具有抑制作用，具有抗氧化活性和神经保护作用，具有抗阿尔茨海默病的潜力。

Kuwanon A 抑制一氧化氮的产生 (IC50: 10.5 μM)。Kuwanon A 是从桑树 (Morus alba L.) 中分离出来的黄酮衍生物。

3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone 是一种来自桑叶的黄酮类化合物，具有细胞毒性，可诱导细胞凋亡。

Sanggenol L 是一种来自是桑树根皮的化合物，抑制细胞生长，通过激活半胱天冬酶级联反应和细胞凋亡诱导因子促进黑色素瘤皮肤癌细胞的凋亡细胞死亡。 Sanggenol L 具有抗癌活性和抗增殖作用，可用于研究前列腺癌。

Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells agai

Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α² and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.

Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.

Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exhibits potent in vitro inhibitory ac

cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage.

Mulberrofuran K shows potent anti-oxidation activities.

Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation of melan-a cells, it also exhibits superoxide scavenging activity that is involved in the protection against auto-oxidation, suggests that mulberroside F may be us

Zarzissine exhibits cytotoxicity against three human and murine tumor cell lines.

2',4'-Dihydroxy-7-methoxy-8-prenylflavan 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2720，CAS号为 331954-16-6。

Mulberrofuran H exhibits potent antifungal activity against phytopathogenic fungi Colletotrichum orbiculare, Phytophthora capsici, Corynespora cassiicola and Fusarium oxysporum.

Sanggenon N shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 23.45 ± 4.72 uM. It inhibits lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages.

trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening o

Kuwanon B belongs to the class of organic compounds known as 3-prenylated flavones. Within the cell, kuwanon B is primarily located in the membrane (predicted from logP). Outside of the human body, kuwanon b can be found in fruits. This makes kuwanon b a

Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation.

Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.