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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TNNI3K Polyclonal Antibody

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货号 TMAB-13654

Anti-TNNI3K Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNNI3K。Anti-TNNI3K Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-TNNI3K Polyclonal Antibody

Anti-TNNI3K Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13654

Anti-TNNI3K Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNNI3K。Anti-TNNI3K Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNNI3K Polyclonal Antibody is a Rabbit antibody targeting TNNI3K. Anti-TNNI3K Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Expressed at lower levels in the cytoplasm.
组织特异性Highly expressed in both adult and fetal heart.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景TNNI3K, also known as CARK, is a 936 amino acid serine/threonine-protein kinase that is highly expressed in heart. Overexpression of TNNI3K leads to improved cardiac function by enhancing beating frequency and increasing contractile force and epinephrine response. TNNI3K suppresses phosphorylation of cardiac troponin I and p38/JNK-mediated apoptosis, therefore protecting the myocardium from ischemic injury. Administration of TNNI3K to mice with myocardial infarction improves cardiac performance and attentuates ventricular remodeling, suggesting that TNNI3K could be a promising target in the treatment of cardiac diseases. There are four isoforms of TNNI3K that are produced as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TNNI3K
抗原种属
Human
基因名称
TNNI3K
基因ID
51086
蛋白名称
Serine/threonine-protein kinase TNNI3K
Uniprot ID
Q59H18
功能
May play a role in cardiac physiology.
化学信息
分子量Theoretical: 93 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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