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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-THRB Polyclonal Antibody

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货号 TMAB-13516

Anti-THRB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 THRB。Anti-THRB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM,ELISA。

Anti-THRB Polyclonal Antibody

Anti-THRB Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13516

Anti-THRB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 THRB。Anti-THRB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM,ELISA。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-THRB Polyclonal Antibody is a Rabbit antibody targeting THRB. Anti-THRB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM,ELISA.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIFFCMELISA
推荐剂量
IHC-P: 1:200-800; IHC-Fr: 1:400-800; IF: 1:100-500; FCM: 1μg/Test; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the biological activities of thyroid hormone (T3). Thyroid hormone receptor b2 (TRb2) is a high affinity receptor for triiodothyronine which belongs to the nuclear hormone receptor family and the NR1 subfamily. It is composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain. Defects in the receptor result in generalized thyroid hormone resistance (GTHR). GTHR is transmitted as an autosomal dominant trait, but an autosomal recessive form also exists. The disease is characterized by goiter, abnormal mental functions, increased susceptibility to infections, abnormal growth and bone maturation, tachycardia and deafness. GTHR patients also have high levels of circulating thyroid hormones (T3-T4), with normal or slightly elevated thyroid stimulating hormone.
抗原信息
免疫原
Recombinant Protein: human THRB protein
抗原种属
Human
基因名称
THRB
基因ID
7068
蛋白名称
Thyroid hormone receptor beta
Uniprot ID
P10828
功能
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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