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Anti-SIRT5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIRT5。Anti-SIRT5 Polyclonal Antibody 可用于 WB,FCM。
Anti-SIRT5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIRT5。Anti-SIRT5 Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-SIRT5 Polyclonal Antibody is a Rabbit antibody targeting SIRT5. Anti-SIRT5 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion matrix. Mitochondrion intermembrane space. |
| 组织特异性 | Widely expressed. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Sirtuins (SIRT1-7) are human homologs of the yeast Sir2 (silent information regulator-2) protein and are divided into four main classes: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. In S. cerevisiae, Sir2 deacetylates histones in an NAD-dependent manner, which regulates silencing at the telomeric, rDNA (ribosomal RNA) and silent mating-type loci. The human SIRT proteins are NAD-dependent deacetylases that act as intracellular regulators and are thought to have ribosyltransferase activity. SIRT5 (NAD-dependent deacetylase sirtuin-5), also known as SIR2L5, is a 310 amino acid member of the class III sirtuins. Localized to mitochrondria and expressed throughout the body, SIRT5 is an NAD-dependent deacetylase that may link metabolic aging processes in humans. SIRT5 contains one deacetylase-sirtuin-type domain and can be deactivated by suramin, a drug that blocks the binding of various growth factors. Two isoforms of SIRT5 exist due to alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human SIRT5 |
| 抗原种属 | Human |
| 基因名称 | SIRT5 |
| 基因ID | |
| 蛋白名称 | NAD-dependent protein deacylase sirtuin-5, mitochondrial |
| Uniprot ID |
| 分子量 | Theoretical: 30 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |