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Anti-SIRT5 Polyclonal Antibody

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货号 TMAB-12818

Anti-SIRT5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIRT5。Anti-SIRT5 Polyclonal Antibody 可用于 WB,FCM。

Anti-SIRT5 Polyclonal Antibody

Anti-SIRT5 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12818

Anti-SIRT5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SIRT5。Anti-SIRT5 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-SIRT5 Polyclonal Antibody is a Rabbit antibody targeting SIRT5. Anti-SIRT5 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion matrix. Mitochondrion intermembrane space.
组织特异性Widely expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Sirtuins (SIRT1-7) are human homologs of the yeast Sir2 (silent information regulator-2) protein and are divided into four main classes: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. In S. cerevisiae, Sir2 deacetylates histones in an NAD-dependent manner, which regulates silencing at the telomeric, rDNA (ribosomal RNA) and silent mating-type loci. The human SIRT proteins are NAD-dependent deacetylases that act as intracellular regulators and are thought to have ribosyltransferase activity. SIRT5 (NAD-dependent deacetylase sirtuin-5), also known as SIR2L5, is a 310 amino acid member of the class III sirtuins. Localized to mitochrondria and expressed throughout the body, SIRT5 is an NAD-dependent deacetylase that may link metabolic aging processes in humans. SIRT5 contains one deacetylase-sirtuin-type domain and can be deactivated by suramin, a drug that blocks the binding of various growth factors. Two isoforms of SIRT5 exist due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SIRT5
抗原种属
Human
基因名称
SIRT5
基因ID
蛋白名称
NAD-dependent protein deacylase sirtuin-5, mitochondrial
Uniprot ID
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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