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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Renalase Antibody (2K659)

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货号 TMAB-12187

Anti-Renalase Antibody (2K659) 是一种 Rabbit 抗体，靶向 Renalase。Anti-Renalase Antibody (2K659) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Renalase Antibody (2K659)

Anti-Renalase Antibody (2K659)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12187

Anti-Renalase Antibody (2K659) 是一种 Rabbit 抗体，靶向 Renalase。Anti-Renalase Antibody (2K659) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Renalase Antibody (2K659) is a Rabbit antibody targeting Renalase. Anti-Renalase Antibody (2K659) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2K659
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney.
抗原信息
免疫原
A synthesized peptide: human Renalase
抗原种属
Human
基因名称
RNLS
基因ID
55328
蛋白名称
Renalase
Uniprot ID
Q5VYX0
功能
Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis (By similarity). According to PubMed:17385068, is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity.
化学信息
分子量Theoretical: 38 kDa. Actual: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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