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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DNAJC3 Polyclonal Antibody

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货号 TMAB-05242

Anti-DNAJC3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DNAJC3。Anti-DNAJC3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DNAJC3 Polyclonal Antibody

Anti-DNAJC3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05242

Anti-DNAJC3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DNAJC3。Anti-DNAJC3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-DNAJC3 Polyclonal Antibody is a Rabbit antibody targeting DNAJC3. Anti-DNAJC3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum.
组织特异性Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DNAJC3 may act as an inhibitor of both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2/PKR to catalyze phosphorylation of the EIF2A. It also functions as a Co-chaperone of HSPA8/HSC70 and is involved in the unfolded protein response (UPR) during ER stress. It has been reported that this protein stimulates the ATPase activity of HSPA8/HSC70.DNAJC3 is also involved in ativiral defense - it is activated in response to infection by influenza virus through the dissociation of DNAJB1. DNAJC3 is widely expressed and can be found at high levels in the testis and pancreas (expression in cell lines is variable).
抗原信息
免疫原
KLH conjugated synthetic peptide: human p58ipk
抗原种属
Human
基因名称
DNAJC3
基因ID
5611
蛋白名称
DnaJ homolog subfamily C member 3
Uniprot ID
Q13217
功能
Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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