sulfated

CCK (26-30) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% when used at a concentration of 0.1 mM.

CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% when used at a concentration of 0.1 mM.

Acetyl-Hirudin (54-65) (sulfated) directly binds to thrombin-rHCII(L444R) and hinders the interaction between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin, which stabilizes the complex.

Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2 1.Niehrs, C., Huttner, W.B., Carvallo, D., et al.Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferasesJ. Biol. Chem.265(16)9314-9318(1990) 2.Payne, M.H., Krstenansky, J.L., Yates, M.T., et al.Positional effects of sulfation in hirudin and hirudin PA related anticoagulant peptidesJ. Med. Chem.34(3)1184-1187(1991)

CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.

CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 uMol/kg.

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) 是一种具有高亲和力的Hirugen类肽，其与凝血酶的KD值小于100 nM。作为抗血栓剂，它能有效抑制凝血酶诱导的纤维蛋白凝块生成，其IC50值为0.087 μM。

CCK Octapeptide, non-sulfated acetate 是一种合成的胆囊收缩素脱硫酸肽。

Hirudin (55-65) (sulfated) 为 Hirudin 的一种抗凝血片段，是一种特定的凝血酶抑制剂，具体作用为阻止血液凝固。

[Thr28, Nle31]-Cholecystokinin (25-33) 是一种具备CCK8所有生物活性的胆囊收缩素 (CCK) 类似物，表现出食欲抑制功效。它在胃肠道系统和中枢神经系统中担任激素和神经递质角色。此肽通过 Thr28 和 Nle31 的特殊替代，展现出在酸性条件下的高稳定性，并能抵抗空气氧化（防止蛋氨酸受损）。其主要构象特征为以Thr4为核心的γ转角和Gly5分隔的C末端螺旋片段。

Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) 是一种由8个氨基酸组成的胆囊收缩素-8。

De-N-sulfated heparin (Heparin I-H) sodium salt 是一种高纯度生化试剂，适合作为生物材料或有机合成中间体，广泛应用于生命科学领域的研究与实验。

Cholecystokinin Octapeptide, desulfated TFA, is a synthetic octapeptide derived from Cholecystokinin (CCK) that has undergone desulfation.

Caerulein, desulfated TFA is Caerulein after desulfurization.Caerulein is a deceptide with the same five carboxy-terminating amino acids as gastrin and cholecystatin (CCK)..

Caerulein, desulfated (FI-6934, desulfated) 是 Caerulein 水解后形成的脱硫化合物，是一种神经肽，具有较低的平滑肌活性，可刺激脂肪酶分泌，抑制胃酸分泌。

Caerulein, desulfated ammonium 是 Caerulein 水解后形成的脱硫 Caerulein，是一种神经肽，具有较低的平滑肌活性，可刺激脂肪酶分泌，抑制胃酸分泌。

Quinidine sulfate dihydrate (Pitayine Sodium) 是抗心律失常剂，能够阻断 K+通道(IC50:19.9 μM)。它是细胞色素 P450db 的选择性抑制剂，可用于研究疟疾。

Quinine sulfate dihydrate 在钾通道阻滞剂中起主要作用。它也被用作抗疟疾、抗胆碱能、抗高血压和降糖药。它抑制线粒体atp 调节的钾通道。它也被用来研究生物结晶血红素，血红素，在疟疾寄生虫的代谢和研究血红素(FP)复合物的毒性。

Lithocholic acid 3-sulfate disodium (Sulfolithocholic acid disodium) 可作为 RORgammat 配体，抑制 Th17 细胞分化。Lithocholic acid 3-sulfate disodium 是石胆酸（LCA）的硫酸化产物，可诱导细胞损伤。

AZ1366 is a potent tankyrase inhibitor that enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Combination AZ1366 and irinotecan achieved greater anti-tumor effects compared to monotherapy. Activity was limited to CRC explants that displayed irinotecan resistance and increased protein levels of tankyrase and NuMA.

Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40 6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). It also inhibits the organic anion transporter (OAT) isoforms OAT1 and OAT3 (Kis = 34.2 and 74.4 µM, respectively for the rat transporters) in S2 proximal tubule cells. Indoxyl sulfate (0.2 and 1 mM) increases superoxide anion and nitric oxide levels in isolated human mononuclear blood cells. It increases serum creatinine and blood urea nitrogen (BUN) levels in the 5 6 nephrectomized rat model of chronic renal failure when administered at a dose of 50 mg kg.

Glycolithocholic acid 3-sulfate (disodium) 是抑制HIV-1复制的化合物，同时它也被用于HIV感染和胆囊疾病的研究。

Chenodeoxycholic acid 3-sulfate disodium, a bile acid, closely corresponds with the extent of hepatic dysfunction [1].

N-β-D-Glucopyranosyloctanamide 一种在生化反应中使用的试剂。