sodium chloride

Sodium chloride，符合Ph. Eur. BP USP的分析规格，含铝量≤0.00002%，是一种无机盐，可作为生化试剂用于生命科学研究。

Cyclopenthiazide (Cyclomethiazide) 是一种噻嗪类利尿剂，用于治疗高血压和心力衰竭。减少钙离子和尿酸的排泄，增加钠和钾离子的排泄。

Maralixibat Chloride (LUM001 chloride) 是一种钠依赖性的胆汁酸转运抑制剂，可阻止胆汁酸在肠肝内的再循环

Trichlormethiazide (Naqua) 是一种口服具有活力的噻嗪类利尿剂，具有降压作用。它能够提高急性肾功能衰竭大鼠的尿量、Na 和 K 排泄，并有改善降低的肌酐清除率。

Meticrane (Arresten) 是一种磺胺类衍生物，具有类似噻嗪类利尿剂的活性，可于研究原发性高血压。

QX-314 chloride 是钠离子通道电荷阻滞剂，具有膜不渗透性。

Inulin 是一种自菊科和百合科植物的贮藏多糖，是非消化性碳水化合物果聚糖。它通常用作益生元，糖替代品，脂肪替代品，质地改良剂，在胃中起有益作用。

QX-222 chloride (Lidocaine N-Methyl Hydrochloride) 是 Lignocaine 的一种三甲基类似物，是有效的 Na+通道阻滞剂。

Chlorazanil hydrochloride 是Chlorazanil 的盐酸盐形式。Chlorazanil 为三嗪衍生物，是一种口服有效的利尿剂，可以阻止钠和氯在远曲小管的吸收。

Chlorazanil 是一种三嗪衍生物，也是一种口服有效的新型非毒性利尿剂，可以阻止钠和氯在远曲小管的吸收。

Ethacrynate Sodium, the sodium salt form of ethacrynic acid, could inhibit symport of chloride, potassium, and sodium primarily in the ascending limb of Henle, but also in the proximal and distal tubules.

AY 31906 is a high ceiling diuretic with a relative potassium-sparing effect. AY 31906 has been shown to produce significant increases in the fractional excretion of sodium and chloride in dogs at a dose that produces no statistically significant changes

Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulation in mice when administered intradermally at doses ranging from 1 to 300 nmol site, which is inhibited by the BB2 bombesin receptor agonist RC-3095 and reduced in mast cell-deficient mice. Neuromedin C (3.2 nmol kg, i.p.) reduces rat glucose consumption by approximately 50% for up to one hour.

Hydrochlorothiazide impurity C is a potential impurity found in commercial hydrochlorothiazide preparations. [1] Hydrochlorothiazide is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter in the distal and collecting duct nephron segments.[2][3][4]

5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.

Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotransporter in the distal convoluted tubule of the kidney, which prevents reabsorption of sodium and chloride leading to a reduction in plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including the isoforms CAVB, VII, IX, XII, and XIII (Kis = 2.8-23 nM) and, to a lesser extent, CAI, CAII, IV, VA, and VI (Kis = 138-1,347 nM), which may mediate its sustained vasodilatory activity. Dietary administration of chlorthalidone (8 mg per animal per day) reduces arterial hypertension and prevents or reduces ventricular hypertrophy induced by deoxycorticosterone acetate (DOCA) in salt-hypertensive rats. Formulations containing chlorthalidone have been used alone or in combination with other antihypertensive agents to lower arterial blood pressure and as adjuvants to address edema caused by cardiac or renal disorders.

Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 cells expressing human and rat UT (EC50s = 0.47 and 0.78 nM, respectively) but decreases intracellular calcium concentration in goby (G. mirabilis) enterocytes when used at a concentration of 500 nM.2Urotensin II (20 mU/ml) stimulates active sodium and chloride absorption across isolated goby posterior intestine in 5% seawater-adapted solution.3In vivo, urotensin II (1.5-150 nmol/kg) decreases diastolic blood pressure and increases heart rate in anesthetized rats.4It also reduces the pressor responses to sympathetic nerve stimulation, norepinephrine , and vasopressin in pithed rats when administered at a dose of 150 nmol/kg. 1.Ames, R.S., Sarau, H.M., Chambers, J.K., et al.Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14Nature401(6750)282-286(1999) 2.Loretz, C.A., and Assad, J.A.Urotensin II lowers cytoplasmic free calcium concentration in goby enterocytes: Measurements using quin2Gen. Comp. Endocrinol.64(3)355-361(1986) 3.Loretz, C.A., Freel, R.W., and Bern, H.A.Specificity of response of intestinal ion transport systems to a pair of natural peptide hormone analogs: Somatostatin and urotensin IIGen. Comp. Endocrinol.52(2)198-206(1983) 4.Gibson, A., Wallace, P., and Bern, H.A.Cardiovascular effects of urotensin II in anesthetized and pithed ratsGen. Comp. Endocrinol.64(3)435-439(1986)

Bumetanide sodium is a potent loop diuretic that acts as a blocker for the sodium-potassium-chloride cotransporter (NKCC). It selectively inhibits NKCC1 and NKCC2, with IC50 values of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively [1] [2].

Taplucainium chloride is a sodium channel blocker with applications as a pain reliever.

Peginterferon α-2a (PEG-IFN α2a) 主要用于抑制慢性乙型及丙型肝炎.其配方中含有氯化钠、苯甲醇、吐温 80、醋酸、醋酸钠及注射用水等辅料.

Metolazone-d7 是 Metolazone 的氘代化合物。Metolazone 的 CAS 号为 17560-51-9。Metolazone 具有抗心力衰竭和高血压作用。

3-Methyl-9H-Fluoren-9-one对Sodium- chloride-dependent glycine transporter 2具有抑制活性，广泛应用于生物化学实验和药物合成研究。

Sodium lactate ringer's solution 是一种等渗晶体溶液，用于调节体液、电解质及酸碱平衡，并在围手术期 (perioperative) 补液中发挥作用。该溶液由乳酸钠、氯化钠、氯化钾和氯化钙的灭菌水溶液组成 (RL, 130 mEq sodium L, 274 mOsm L)。

Phosphocholine Chloride Sodium Salt 是一种有机化合物，含有磷酸盐、胆碱和氯离子。它主要用于制备药物输送系统中的细胞膜和脂质体。此化合物在制药行业中具有多种用途，尤其是作为稳定剂和表面活性剂。此外，它还被用作乳化剂和调理剂，在化妆品及个人护理产品的生产中发挥作用。