plant pathogenic fungus

Fenhexamid (Elevate) 是一种甾醇生物合成抑制剂，对植物病原真菌具有抗真菌活性。 Fenhexamid 用于农业，并在水果和蔬菜中以可测量的量存在。

Antibacterialagent 184 (compound 4j) 是一种真菌抑制剂，对植物病原真菌核盘菌表现出毒性，其对核盘菌的抑制率超过97% (IR>97%)。

Piliformic acid is a fungal metabolite that has been found inN. pseudotrichiaand has diverse biological activities.1,2It is cytotoxic to BC-1 human breast cancer cells (IC50= 5 μg/ml).2Piloformic acid is active againstL. braziliensisamastigotes (IC50= 78.5 μM). It is also active against the plant pathogenic fungiC. gloeosporioides(MIC = 292 μM).1 1.Elias, L.M., Fortkamp, D., Sartori, S.B., et al.The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnoseBraz. J. Microbiol.49(4)840-847(2018) 2.Cota, B.B., Tunes, L.G., Maia, D.N.B., et al.Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)Mem. Inst. Oswaldo Cruz113(2)102-110(2018)

Pyrenocine A is a fungal metabolite that has been found inP. terrestrisand has diverse biological activities.1It inhibits the asexual spore germination of the plant pathogenic fungiF. oxysporum,F. solani,M. hiemalis, andR. stolonifer(EC50s = 14, 20, 20, and 25 μg/ml, respectively). Pyrenocine A is active againstB. subtilis,S. aureus, andE. coli(IC50s = 30, 45, and 200 μg/ml, respectively). It inhibits onion seedling elongation (EC50= 4 μg/ml). Pyrenocine A is also a phytotoxin that inhibits lettuce seed germination and rice seedling elongation.2,3 1.Sparace, S.A., Reeleder, R.D., and Khanizadeh, S.Antibiotic activity of the pyrenocinesCan. J. Microbiol.33(4)327-330(1987) 2.Sato, H., Konoma, K., and Sakamura, S.Phytotoxins produced by onion pink root fungus, Pyrenochaeta terrestrisAgric. BioI. Chem.43(11)2409-2411(1979) 3.Sato, H., Konoma, K., Sakamura, S., et al.X-Ray crystal structure of pyrenocine A, a phytotoxin from Pyrenochaeta terrestrisAgric. BioI. Chem.45(3)795-797(1981)

Flutolanil is a benzanilide fungicide. It is active against a panel of 241 field isolates of the plant pathogenic fungus R. solani when grown in flutolanil-enriched growth media. Flutolanil inhibits R. solani hyphal growth and infection cushion formation on rice plant leaf sheaths. It is toxic to zebrafish embryos, larvae, and adults. Formulations containing flutolanil have been used to control fungal infections on rice crops.

OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M. gallisepticum, M. pneumoniae, and S. aureus. OM173-αA also inhibits the growth of the plant pathogenic fungus P. oryzae and several species of Trichophyton.

Uridine diphosphate glucuronic acid ammonium (UDP-α-D-glucuronic acid ammonium) 是许多植物细胞壁多糖的前体，是生产种子粘液所必需的。Uridine diphosphate glucuronic acid ammonium 是致病真菌新型隐球菌中荚膜多糖合成的关键代谢物。

Dendryphiellin D，一种从Septoria rudbeckiae分离的化合物，后者为盐生植物Karelinia caspia中提取的植物病原真菌。该化合物显著抑制一氧化氮(NO)的生成。

Septeremophilane E, 从真菌 Septoria rudbeckiae 分离得到，该真菌是盐生植物 Karelinia caspia 的植物病原体。该化合物显著抑制一氧化氮(NO)的产生。

Protoneogracillin 是一种呋甾醇糖苷，具有抑制植物病原真菌 P.oryzae 的活性 (MMDC=94.0 μM)，对 K562 癌细胞的细胞毒活性 (IC50=6.6 μM)。

Fenhexamid (Standard) 是 Fenhexamid 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Fenhexamid (Elevate) 是一种甾醇生物合成抑制剂，对植物病原真菌具有抗真菌活性。 Fenhexamid 用于农业，并在水果和蔬菜中以可测量的量存在。

Kushenol I 具有抗炎、抗氧化及改善溃疡性结肠炎作用。于 DSS 诱导的 UC 小鼠模型中，口服给药可改善结肠长度、体重与疾病评分，同时降低 IL-1β、IL-6、IL-17 与 TNF-α 等炎性因子并增加 IL-10 表达。Kushenol I 抑制 AKT、p38 MAPK、PI3K、NLRP3、FOXO1 与 TLR4 等炎症相关信号，强化肠屏障功能，并可调节肠道菌群及提升脾脏 T 细胞比例，支持其在炎症性肠病中的治疗潜力。

2-Methoxyanofinic acid is active against the plant pathogenic fungus Cladosporium cucumerinum.

Ascochin, an isocoumarin derivative and fungal metabolite identified in Ascochyta, demonstrates antimicrobial activity. At a concentration of 0.5 mg/disc, it inhibits Bacillus megaterium (the bacterium), Mycosphaerella violaceum (the plant pathogenic fungus), and Chlorella fusca (the alga) in agar diffusion assays.

性。Cryptosporiopsin A 对 P.viticola、A.cochliodes、P.ultimum 和R.solani 具有抑制作用（MICs=20、40和50 µg/ml）。