mt-7

MT-7 is a tubulin polymerization inhibitor.

MT-7716 free base is a selective non-peptide agonist of nociceptin receptor (NOP). It is used for promising potential treatment drugs for alcohol abuse and relapse prevention.

MT-7716 HCl hydrate is a NOP receptor agonist.

MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)

PRMT4-IN-1为PRMT4高选择性抑制剂(IC50=3.2 nM)，能有效降低MCF7细胞的相对活力。

：JS1310 是一种选择性的 PRMT7 抑制剂，对人 PRMT7 的 IC50 为 5 μM。JS1310 对不同癌细胞均表现出抗癌效果。

Dersimelagon phosphate is a selective melanocortin-1 receptor (MC1R) agonist that increases skin melanin without sun exposure and is being developed to increase light tolerance in EPP XLP patients.

DMT7是一种可电离的阳离子脂质（pKa = 6.5），适用于生成脂质纳米颗粒（LNPs），用于在体内递送mRNA和抗癌药物。

S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) 是一种选择性的褪黑激素配体 MT1 和 MT2 拮抗剂，对 MT1 和 MT2 的 Ki 值分别为 0.5 和 112 nM。

3-Oxobetulin acetate is a derivative of the cholesterol biosynthesis inhibitor betulin. It inhibits the growth of P388 murine lymphocytic leukemia cells (EC50 = 0.12 µg ml), as well as human MCF-7 breast, SF-268 CNS, H460 lung, and KM20L2 colon cancer cells (GI50s = 8, 10.6, 5.2, and 12.7 µg ml, respectively), but not BxPC-3 pancreas or DU145 prostate cancer cells (GI50s = >10 µg ml for both). 3-Oxobetulin acetate inhibits replication of X4 tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblastoid cells (IC50 = 13.4 µM). It is also active against L. donovani amastigotes when used at a concentration of 50 µM.