ly6d

LY6D Protein, Mouse, Recombinant (mFc) is expressed in Yeast. The accession number is P35459.

LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane proteins and applies to various biological phenomena in situations in which both target molecule-expressing cells and nonexpressing cells are available. Diseases associated with LY6D include Alzheimer's Disease 16 and Inferior Myocardial Infarction.

Expression system: HEK293 Cells
Length: 20-104, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 20-104, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 20-104, Full Length of Mature Protein
Activity: ELISA

LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. LY6G6D Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 10.22 kDa and the accession number is XP_045246087.1.