anti-insect

Isoasatone A 是一种具有抗虫作用的天然产物，分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶，产生抗S. litura 作用。

Itch-Targeting Compound 1是一种止痒化合物，对昆虫叮咬的反应、对环境过敏原的反应、皮肤感染、外部恶臭或肾透析患者发生的瘙痒均可有效预防或治疗。

Thiacloprid 属于氯烟碱类杀虫剂，主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性，通过疏水或氢相互作用，结合到小沟槽中，改变 DNA 的结构和稳定性。

Nerolidol acetate是一种具有抗癌、抗炎、抗菌和抗虫的活性的天然倍半萜。Nerolidol acetate可抑制寄生虫活动，抑制吸血虫病、线虫病以及疟疾等。Nerolidol acetate可保护细胞免受脂质、蛋白质和 DNA 的氧化损伤，对小鼠海马神经细胞具有保护作用。

Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. cervinatalarvae weight gain and food consumption. 1.Gallagher, R.T., Latch, G.C., and Keogh, R.G.The janthitrems: Fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pasturesAppl. Environ. Microbiol.39(1)272-273(1980) 2.Babu, J.V., Popay, A.J., Miles, C.O., et al.Identification and structure elucidation of janthitrems A and D from Penicillium janthinellum and determination of the tremorgenic and anti-insect activity of janthitrems A and BJ. Agric. Food Chem.66(50)13116-13125(2018)

7(Z)-Tricosene是一种昆虫信息素和内源性代谢物，用于交配和种间识别。

ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.

Juvenile hormone B 3 (Juvenile hormone III bisepoxide) (mixture of diastereomers) 是一种倍半萜类激素。它可以从果蝇和黑腹果蝇等高等双翅目昆虫的翅体 (CA) 中分离，具有抗变态活性。Juvenile hormone B 3 (mixture of diastereomers) 通过与幼虫激素 (JH) 受体 (Met和Gce) 的直接作用，诱导Kr-h1的表达，可用于昆虫致死性研究。

Arjunetin是一种发现于Terminalia arjuna的天然产物，对SARS-CoV-2具有结合亲和力，具有潜在的抗病毒活性。

Lactupicrin是一种发现于Chicory的天然产物，具有镇痛、镇静、抗疟疾和保护动脉粥样硬化的作用,能够抑制NF-κB活化和LDLR1生成，对酵母的Alpha-glucosidase具有抑制作用(IC50= 14.71 µM)。

Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect

Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.

Rubrosterone is a steroid and C19 steroid found in certain plants and insects, exhibiting anti-diabetic activity.

Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemical barrier against the intrusion of the parasite.