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Search Results for " duocarmycin sa "
Targets Recommended: Others ADC Cytotoxin

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Cat. No. Product Name Target Signaling Pathways
T11118 Duocarmycin SA

Others; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Others
Duocarmycin SA is an extremely potent cytotoxic agent and antitumor antibiotic that induces sequence-selective alkylation of duplex DNA, with an IC50 of 10 pM. It demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells when combined with proton radiation in vitro.
T12813L Seco-Duocarmycin SA

DNA Alkylation; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.
T12813 (S)-Seco-Duocarmycin SA

Others; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Others
(S)-Seco-Duocarmycin SA is a DNA alkylator, acts as a ADC cytotoxin for antibody-drug conjugates.
T18293 Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA

Others; Drug-Linker Conjugates for ADC Antibody-drug Conjugate/ADC Related; Others
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker that incorporates the antitumor antibiotic Duocarmycin SA, connected through the Mal-PEG4-VC-PAB-DMEA-Seco linker, for targeted cancer therapy.

化合物

Duocarmycin SA
Cat.No: T11118
Synonym:
Target: Others, ADC Cytotoxin
Seco-Duocarmycin SA
Cat.No: T12813L
Synonym:
Target: DNA Alkylation, ADC Cytotoxin
(S)-Seco-Duocarmycin SA
Cat.No: T12813
Synonym:
Target: Others, ADC Cytotoxin
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
Cat.No: T18293
Synonym:
Target: Others, Drug-Linker Conjugates for ADC
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