首页 工具
登录

搜索结果

Search Results for "CDKI-73"
Targets Recommended: CDK Apoptosis

1

抑制剂 & 化合物

61

化合物库

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

Cat. No. Product Name
CL0056 CDK inhibitor kit

CL0137 E1/E2/E3 Enzyme inhibitor kit

CL0136 ATM/ATR inhibitor kit

L1610 FDA 上市激酶抑制剂库

280 compounds
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、RAF、EGFR、MEK、SAPK、GSK、MLCK、Src-family、IKK、PDGFR、VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.
CL0067 Sodium Channel inhibitor kit

L1600 激酶抑制剂库

2230 compounds
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
L3400 临床期小分子药物库

3142 compounds
A unique collection of 3142 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS);
L6900 稀有天然产物库

284 compounds
A unique collection of 284 rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS);
L2191 抗乳腺癌化合物库

1965 compounds
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;
L8100 细胞周期化合物库

695 compounds
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
NY1000 天然产物衍生物库

4000 compounds
The library consists of more than 4,000 members belonging 22 scaffolds (average 180 compounds per scaffold).
L9411 半胱氨酸共价化合物库

72 compounds
The cysteine ​​covalent library contains 72 compounds.
DC1170 特权片段注释化合物库-Oxidoreductases

DC1150 特权片段注释化合物库-GPCR Family B

DC1100 特权片段注释化合物库-GPCR Frizzled family

DC1030 特权片段注释化合物库-Epigenetics

DC1200 特权片段注释化合物库-Isomerases

DC1040 特权片段注释化合物库-Transferases

DC1140 特权片段注释化合物库-Ligand-gated

DC1190 特权片段注释化合物库-Sigma Opioid receptors

DC1180 特权片段注释化合物库-Lyases

DC1050 特权片段注释化合物库-Voltage-gated

DC1010 特权片段注释化合物库-GPCR Family A

DC1160 特权片段注释化合物库-Toll-like and Il-1 receptors

DC1060 特权片段注释化合物库-Kinases

DC1220 特权片段注释化合物库-Aminoacyltransferases

DC1000 特权片段注释化合物库

DC1110 特权片段注释化合物库-Proteases

DC1210 特权片段注释化合物库-Phosphatases

CL0103 mGluR agonist/antagonist/modulator kit

DC1130 特权片段注释化合物库-Phosphodiesterases

DC1090 特权片段注释化合物库-Ligases

DC1230 特权片段注释化合物库-Beta amyloid A4 protein

DC1020 特权片段注释化合物库-Spiro Library

DC1080 特权片段注释化合物库-GPCR Taste family

DC1070 特权片段注释化合物库-GPCR Family C

DC1120 特权片段注释化合物库-Thrombopoietin receptors

CL0102 Akt inhibitor/activator kit

DQ3000 Factor XIa化合物库

CL0139 ROS inhibitor kit

CL0068 VEGFR inhibitor kit

CL0126 Androgen Receptor antagonist kit

L6020 天然产物单体化合物库

CL0132 DHFR inhibitor kit

CL0061 Histone Methyltransferase inhibitor kit

L6700 抗癌天然产物库

1800 compounds
A unique collection of 1800 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
CL0059 Dopamine Receptor inhibitor kit

L1380 转录因子库

704 compounds
Well-chosen 704 compounds with unique structures targeting transcription factor;
L8400 血液病分子库

524 compounds
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
DF4600 类药性天然产物库

L6400 海洋天然产物库

94 compounds
A unique collection of 94 marine natural products for high throughput screening (HTS) and high content screening (HCS);
L1580 GPCR库Plus

338 compounds
Well-chosen 338 GPCR targeting compounds with unique structures;
L2196 抗卵巢癌化合物库

1888 compounds
L1500 GPCR靶点分子库

1633 compounds
A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;
L9830 抗帕金森病化合物库

908 compounds
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
VM1400 多样性核心库Part2

DF4500 多样性核心库Part1

L2190 抗肺癌化合物库

1735 compounds
A unique collection of 1735 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study;
L6030 天然产物衍生物虚筛化合物库

L9410 共价抑制剂库

941 compounds
A unique collection of 941 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.
CL0092 GSK-3 inhibitor kit

化合物库

CDK inhibitor kit
CL0056
Compounds: 0
E1/E2/E3 Enzyme inhibitor kit
CL0137
Compounds: 0
ATM/ATR inhibitor kit
CL0136
Compounds: 0
FDA 上市激酶抑制剂库
L1610
Compounds: 280
Sodium Channel inhibitor kit
CL0067
Compounds: 0
激酶抑制剂库
L1600
Compounds: 2230
临床期小分子药物库
L3400
Compounds: 3142
稀有天然产物库
L6900
Compounds: 284
抗乳腺癌化合物库
L2191
Compounds: 1965
细胞周期化合物库
L8100
Compounds: 695
天然产物衍生物库
NY1000
Compounds: 4000
半胱氨酸共价化合物库
L9411
Compounds: 72
特权片段注释化合物库-Oxidoreductases
DC1170
Compounds: 0
特权片段注释化合物库-GPCR Family B
DC1150
Compounds: 0
特权片段注释化合物库-GPCR Frizzled family
DC1100
Compounds: 0
特权片段注释化合物库-Epigenetics
DC1030
Compounds: 0
特权片段注释化合物库-Isomerases
DC1200
Compounds: 0
特权片段注释化合物库-Transferases
DC1040
Compounds: 0
特权片段注释化合物库-Ligand-gated
DC1140
Compounds: 0
特权片段注释化合物库-Sigma Opioid receptors
DC1190
Compounds: 0
特权片段注释化合物库-Lyases
DC1180
Compounds: 0
特权片段注释化合物库-Voltage-gated
DC1050
Compounds: 0
特权片段注释化合物库-GPCR Family A
DC1010
Compounds: 0
特权片段注释化合物库-Toll-like and Il-1 receptors
DC1160
Compounds: 0
特权片段注释化合物库-Kinases
DC1060
Compounds: 0
特权片段注释化合物库-Aminoacyltransferases
DC1220
Compounds: 0
特权片段注释化合物库
DC1000
Compounds: 0
特权片段注释化合物库-Proteases
DC1110
Compounds: 0
特权片段注释化合物库-Phosphatases
DC1210
Compounds: 0
mGluR agonist/antagonist/modulator kit
CL0103
Compounds: 0
特权片段注释化合物库-Phosphodiesterases
DC1130
Compounds: 0
特权片段注释化合物库-Ligases
DC1090
Compounds: 0
特权片段注释化合物库-Beta amyloid A4 protein
DC1230
Compounds: 0
特权片段注释化合物库-Spiro Library
DC1020
Compounds: 0
特权片段注释化合物库-GPCR Taste family
DC1080
Compounds: 0
特权片段注释化合物库-GPCR Family C
DC1070
Compounds: 0
特权片段注释化合物库-Thrombopoietin receptors
DC1120
Compounds: 0
Akt inhibitor/activator kit
CL0102
Compounds: 0
Factor XIa化合物库
DQ3000
Compounds: 0
ROS inhibitor kit
CL0139
Compounds: 0
VEGFR inhibitor kit
CL0068
Compounds: 0
Androgen Receptor antagonist kit
CL0126
Compounds: 0
天然产物单体化合物库
L6020
Compounds: 0
DHFR inhibitor kit
CL0132
Compounds: 0
Histone Methyltransferase inhibitor kit
CL0061
Compounds: 0
抗癌天然产物库
L6700
Compounds: 1800
Dopamine Receptor inhibitor kit
CL0059
Compounds: 0
转录因子库
L1380
Compounds: 704
血液病分子库
L8400
Compounds: 524
类药性天然产物库
DF4600
Compounds: 0
海洋天然产物库
L6400
Compounds: 94
GPCR库Plus
L1580
Compounds: 338
抗卵巢癌化合物库
L2196
Compounds: 1888
GPCR靶点分子库
L1500
Compounds: 1633
抗帕金森病化合物库
L9830
Compounds: 908
多样性核心库Part2
VM1400
Compounds: 0
多样性核心库Part1
DF4500
Compounds: 0
抗肺癌化合物库
L2190
Compounds: 1735
天然产物衍生物虚筛化合物库
L6030
Compounds: 0
共价抑制剂库
L9410
Compounds: 941
GSK-3 inhibitor kit
CL0092
Compounds: 0
Cat. No. Product Name Target Signaling Pathways
T14919 CDKI-73

CDK; Apoptosis Apoptosis; Cell Cycle/Checkpoint
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.

化合物

CDKI-73
T14919
synonym:
Target: CDK, Apoptosis