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8

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T30601 BTC

BTC is a human G-quadruplexes regulator, inducing dynamic transitions between the ensembles of unfolded conformations to the folded state in G-quadruplexes, altering the rod shaped DNA sequences into globular quadruplexes with a decrease in hydrodynamic r
T37188 BTC AM

BTC AM is a cell-permeable acetoxy-methyl ester of BTC . As BTC AM enters cells, it is hydrolyzed by intracellular esterases to produce BTC. BTC is a low affinity calcium indicator (Kd = 7-26 μM) that displays excitation/emission spectra of 401/529 nm, respectively. It exhibits a shift in the excitation maximum from approximately 480 to 401 nm upon calcium binding, enabling determination of ratiometric calcium measurements. BTC is suitable for detecting elevated calcium levels associated with ac...
T82811 BTC tetrapotassium

BTC tetrapotassium是一种钙指示剂,其Kd值约为7-26 µM,表现出低亲和力。它拥有适合细胞钙成像的特性,如长激发波长(400/485 nm),低对Mg2+的灵敏度,以及用于比率测量的高准确性。
T37189 BTCP maleate

BTCP 与豚鼠脑膜一起预孵育可增加 [3H]TCP 从 PCP 位点的解离速率。
T24857 TBTC

TBTC is a selective agonist of retinoid X receptor α that acts by improving behavioral deficit in Alzheimer's disease model mice.
T82810 BTCy

BTCy为一种近红外(NIR)荧光探针,表现出极性响应并具有针对细胞质膜的靶向性。适用于体内肿瘤组织成像(λex= 561 nm, λem= 600-700 nm)。
T39286 Br-PBTC

Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs). It specifically targets α2β2, α2β4, α4β2, α4β4, (α4β2)2α4, and (α4β2)2β2 subtypes of nAChRs, with EC50 values ranging from 0.1 to 0.6 μM. Br-PBTC exerts its activity by binding to the c-tail region of an α subunit.
T37761 Fura-FF (potassium salt)

Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation.[1] Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively).[1],[2]However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presen...

化合物

BTC
Cat.No: T30601
Synonym:
Target:
BTC AM
Cat.No: T37188
Synonym:
Target:
BTC tetrapotassium
Cat.No: T82811
Synonym:
Target:
BTCP maleate
Cat.No: T37189
Synonym:
Target:
TBTC
Cat.No: T24857
Synonym:
Target:
BTCy
Cat.No: T82810
Synonym:
Target:
Br-PBTC
Cat.No: T39286
Synonym:
Target:
Fura-FF (potassium salt)
Cat.No: T37761
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00058 BTC Protein, Mouse, Recombinant (His)

βcellulin,isoform CRA_a,Btc,Betacellulin,mCG_12529

Mouse E. coli
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Betacellulin is characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family. Betacellulin is expressed in several tissues and tumor cells including kidney, uterus, liver, pancreas and small intestine....
TMPY-01323 Betacellulin Protein, Mouse, Recombinant (His & hFc)

Bcn,betacellulin,βcellulin

Mouse HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of abou...
TMPY-06597 Betacellulin Protein, Rhesus, Recombinant (hFc)

betacellulin,βcellulin

Rhesus HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of abou...
TMPY-03569 Betacellulin Protein, Human, Recombinant (hFc)

betacellulin,βcellulin

Human HEK293
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of abou...

重组蛋白

BTC Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00058
Species: Mouse
Expression System: E. coli
Betacellulin Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01323
Species: Mouse
Expression System: HEK293
Betacellulin Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-06597
Species: Rhesus
Expression System: HEK293
Betacellulin Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03569
Species: Human
Expression System: HEK293
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