血管内皮生长因子家族 (Vascular Endothelial Growth Factors, VEGFs)

Expression system: Baculovirus Insect Cells
Length: 1-191, Full Length
Activity: Cell Activity

Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF) vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessels and endothelial cell growth, increasing microvascular permeability, promoting cell migration and inhibiting apoptosis. Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms. The lymphangiogenesis may be promoted by upregulation of VEGF121, which may in turn act in part via induction of VEGF-C. It binds to the FLT1 VEGFR1 and KDR VEGFR2 receptors, heparan sulfate and heparin. NRP1 Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

VEGFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is O43915.

PLGF PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.

VEGFC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P49767.

Expression system: HEK293 Cells
Length: 108-223, Full Length of Mature Protein
Activity: ELISA、Cells

Expression system: HEK293 Cells
Length: 22-207, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 27-191, Full Length of Mature Protein of Isoform VEGF165
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 27-191, Full Length of Mature Protein of Isoform VEGF165
Activity: ELISA

Expression system: HEK293 Cells
Length: 27-191, Full Length of Mature Protein of Isoform VEGF165
Activity: ELISA

VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.

VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.

PLGF PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.

VEGF165 Protein, Danio rerio (zebrafish), Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is O73682.

VEGF165B Protein, Human, Recombinant is expressed in Baculovirus-Insect Cells. The accession number is P15692-8.

VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.

VEGF164 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli. The accession number is Q00731-2.

VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.

VEGF121 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is P15692-9.

VEGFD Protein, Human, Recombinant is expressed in CHO Cells. The accession number is O43915.

Expression system: P. pastoris (Yeast)
Length: 51-511, Full Length of Mature Protein
Activity: Not Tested

Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.

VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9.

VEGF110 Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is NP_001191313.1.