| Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T17706 | BzNH-BS
化合物 T17706
|
T17706 | 98% |
|
| BzNH-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide, which are connected by linkers. MeBS as a ligand for cellular inhibit... | ||||
| T16905 | SNIPER(BRD)-1
化合物 T16905
|
2095244-54-3 | 98% |
|
| SNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation of BR... | ||||
| T18689 | SNIPER(ABL)-033
化合物 T18689
|
2222354-18-7 | 98% |
|
| SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of ... | ||||
| T18690 | SNIPER(ABL)-039
化合物 T18690
|
2222354-29-0 | 98% |
|
| SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 1... | ||||
| T17545 | Biotin-BS
化合物 T17545
|
T17545 | 98% |
|
| Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of... | ||||
| T18692 | SNIPER(ABL)-047
化合物 T18692
|
T18692 | 98% |
|
| SNIPER(ABL)-047, conjugating HG-7-85-01 (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 2 μM[1]. | ||||
| T18691 | SNIPER(ABL)-044
化合物 T18691
|
T18691 | 98% |
|
| SNIPER(ABL)-044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].... | ||||
| T13838 | PROTAC CRABP-II Degrader-3
化合物 T13838
|
1225383-41-4 | 98% |
|
| PROTAC CRABP-II Degrader-3 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1. | ||||
| T18693 | SNIPER(ABL)-049
化合物 T18693
|
T18693 | 98% |
|
| SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM[1]. | ||||
| T13891 | SNIPER(TACC3)-1
化合物 T13891
|
T13891 | 98% |
|
| SNIPER(TACC3)-1 targets TACC3 protein degradation via the ubiquitin-proteasome pathway.It induces cancer cell death. | ||||
| T18687 | SNIPER(ABL)-020
化合物 T18687
|
T18687 | 98% |
|
| SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1]. | ||||
| T13837 | PROTAC CRABP-II Degrader-2
化合物 T13837
|
1225383-38-9 | 98% |
|
| PROTAC CRABP-II Degrader-2 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1. | ||||
| T18605 | PROTAC ERα Degrader-2
化合物 T18605
|
1351169-29-3 | 98% |
|
| PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. ... | ||||
| T18686 | SNIPER(ABL)-019
化合物 T18686
|
T18686 | 98% |
|
| SNIPER(ABL)-019, conjugating Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1]. | ||||
| T18635 | PROTAC RAR Degrader-1
化合物 T18635
|
1351169-27-1 | 98% |
|
| PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degr... | ||||
| T18684 | SNIPER(ABL)-013
化合物 T18684
|
T18684 | 98% |
|
| SNIPER(ABL)-013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 20 μM[1]. | ||||
| T18694 | SNIPER(ABL)-050
化合物 T18694
|
T18694 | 98% |
|
| SNIPER(ABL)-050, conjugating Imatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1]. | ||||
| T18695 | SNIPER(ABL)-058
化合物 T18695
|
2222354-61-0 | 98% |
|
| SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10... | ||||
| T13836 | PROTAC CRABP-II Degrader-1
化合物 T13836
|
1225383-40-3 | 98% |
|
| PROTAC CRABP-II Degrader-1 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1. | ||||
| T18688 | SNIPER(ABL)-024
化合物 T18688
|
2222355-77-1 | 98% |
|
| SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM[1]... | ||||
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