Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product Name	CAS No.	Purity
TN4637	Neogrifolin 化合物 TN4637	23665-96-5	98%
TN4637	Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...
TN4683	Nyasol 化合物 TN4683	96895-25-9	98%
TN4683	Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ...
T19378	Ipfencarbazone 三唑酰草胺	212201-70-2	98%
T19378	Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.
TN4179	Haginin A 化合物 TN4179	74174-29-1	98%
TN4179	Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activ...
TN5050	Sprengerinin C 化合物 TN5050	88861-91-0	98%
TN5050	Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
TN5100	Taspine 化合物 TN5100	602-07-3	98%
TN5100	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
T12397	KP-23172 化合物 T12397	331253-86-2	98%
T12397	KP-23172 is a inhibitor of PI3-K/Akt pathway.
TN2691	2',3'-Dehydrosalannol 化合物 TN2691	97411-50-2	98%
TN2691	2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits ca...
TN3539	Broussonin A 化合物 TN3539	73731-87-0	98%
TN3539	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tra...
TN4356	Jolkinolide A 化合物 TN4356	37905-07-0	98%
TN4356	Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly in...
T14152	Akt1 and Akt2-IN-1 化合物 T14152	893422-47-4	98%
T14152	Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
TN3152	6-Acetonyldihydrochelerythrine 化合物 TN3152	22864-92-2	98%
TN3152	6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
TN4245	Icariside D2 化合物 TN4245	38954-02-8	98%
TN4245	Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression o...
TN4213	Hirsutenone 化合物 TN4213	41137-87-5	98%
TN4213	Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
T3229	Cytochalasin D 细胞松弛素D	22144-77-0	98%
T3229	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertiliz...
TN1245	3-Deoxysappanchalcone 3-去氧苏木查尔酮	112408-67-0	98%
TN1245	3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.
TN3323	Monomethyl lithospermate 紫草酸单甲酯	933054-33-2	98%
TN3323	Monomethyl lithospermate (Lithospermic acid monomethyl ester) 具有潜在的抗病毒活性，通过激活PI5K/Akt信号传导，减轻体内大脑中动脉闭塞小鼠缺血性中风损伤，并在体外保护氧葡萄糖剥夺/复氧诱导的SHSY-3Y细胞。Monomethyl lithosperma...
TN3753	Dalbergioidin 化合物 TN3753	30368-42-4	98%
TN3753	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces...
TN1549	Damnacanthal 化合物Damnacanthal	477-84-9	98%
TN1549	Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
TMA0291	Dehydroglyasperin D 化合物 TMA0291	517885-72-2	98%
TMA0291	Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...