Temporin A, a short alpha-helical antimicrobial peptide derived from the skin of Rana temporaria, exhibits a wide-ranging efficacy against Gram-positive bacteria. It directly interacts with the cell membrane of microorganisms and remains non-toxic to erythrocytes at antimicrobial concentrations. Additionally, Temporin A demonstrates antifungal properties against yeast-like Candida albicans.
Temporin L, a potent antimicrobial peptide, exhibits activity against Gram-negative bacteria and yeast strains, as well as demonstrating antiendotoxin properties.