temporin a

Temporin A, a short alpha-helical antimicrobial peptide derived from the skin of Rana temporaria, exhibits a wide-ranging efficacy against Gram-positive bacteria. It directly interacts with the cell membrane of microorganisms and remains non-toxic to erythrocytes at antimicrobial concentrations. Additionally, Temporin A demonstrates antifungal properties against yeast-like Candida albicans.

Temporin L, a potent antimicrobial peptide, exhibits activity against Gram-negative bacteria and yeast strains, as well as demonstrating antiendotoxin properties.

Temporin B作为一种抗菌肽，具有针对Legionella pneumophila的抗菌活性。

Temporin C，一种针对Legionella pneumophila具有抗菌活性的肽类化合物。

Temporin F是针对Legionella pneumophila具有抗菌活性的肽类化合物。

Temporin G为针对Legionella pneumophila具有抗菌活性的肽类化合物。

Temporin K为针对Legionella pneumophila具有活性的抗菌肽。

Temporin-Sha 是一种抗菌肽，具有广泛的生物活性。它对革兰氏阳性菌（如李特斯菌，MIC = 6.25 μM）、革兰氏阴性菌（如大肠杆菌，MIC = 10 μM）以及耐药菌株（如耐Methicillin金黄色葡萄球菌）有效。Temporin-Sha 还对白色念珠菌（MIC = 25 μM）、酿酒酵母（MIC = 12 μM）、利什曼原虫的前鞭毛体和无鞭毛体（IC50 = 9-20 μM）以及锥虫（IC50 = 17 μM）具有抑制作用。此外，Temporin-Sha 对HSV-1具有抗病毒活性，并展示出抗癌效果，在乳腺癌细胞MCF-7和肺癌细胞H460中表现出细胞毒性。