steroidogenesis

Gibberellic acid (GA3) 是由真菌 Gibberella fujikuroi 命名而来。它能够调节植物发育和生长的过程（包括种子发育和发芽，茎和根的生长，细胞分裂和开花时间）。

Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K，是抗寄生虫，抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂，也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。

Phthalic acid mono-2-ethylhexyl ester (Phthalic Acid Monooctyl Ester) 是diethylhexyl phthalate (DEHP) 的主要生物活性代谢物，能够抑制 CYP17 的 17，20 裂合酶特性。

Diethylumbelliferyl phosphate (DEUP) 作为一种选择性的强效胆固醇酯酶抑制剂，能防止胆固醇被运输到类固醇生成细胞的线粒体，从而有效抑制类固醇的生成。在体外环境中，DEUP不会对蛋白激酶活性A造成抑制。此外，其IC50值为 11.6 μM，表明该化合物能够在一定程度上阻止膳食胆固醇的吸收。

Pregnanetriol is a metabolite of 17α-hydroxyprogesterone .1,2It is formed from 17α-hydroxyprogesterone by reduction of the C-20 ketone.2Urinary levels of pregnanetriol are elevated in patients with 21-hydroxylase deficiency and congenital adrenal hyperplasia.3,4 1.Kamrath, C., Hartmann, M.F., Boettcher, C., et al.Diagnosis of 21-hydroxylase deficiency by urinary metabolite ratios using gas chromatography-mass spectrometry analysis: Reference values for neonates and infantsJ. Steroid Biochem. Mol. Biol.15610-16(2016) 2.Schiffer, L., Barnard, L., Baranowski, E.S., et al.Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive reviewJ. Steroid Biochem. Mol. Biol.194105439(2019) 3.Disorders of steroidogenesis guide to steroid profiling and biochemical diagnosis1(2019) 4.Shackleton, C.H.L.Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesisLipids47(1)1-12(2012)

Propylparaben sodium (propyl parahydroxybenzoate) is a naturally occurring antimicrobial preservative found in plants and bacteria. Widely utilized in cosmetics, pharmaceuticals, and foods, this compound impairs antral follicle growth and steroidogenic function by modifying the cell-cycle, apoptosis, and steroidogenesis pathways. Additionally, propylparaben sodium reduces sperm count and motility in rats.

Azastene is a progesterone antagonist that has been shown to inhibit ovarian & adrenal steroidogenesis in rats.

ACTH (6-24) (human)（腎上腺皮質激素（6-24））是腎上腺皮質激素的片段。該化合物作為ACTH (1-39) 和 ACTH (5-24) 引起的類固醇生成的競爭性抑制劑，具有相應的Kd值分別為13.4和3.4nM。此外，ACTH (6-24) (human) 能夠抑制 hPTH 1-34 所誘導的皮質酮產生以及cAMP的累積。