pf 04991532

PF-04991532 is an effective, hepatoselective glucokinase activator. It has EC50s of 80 and 100 nM in human and rat, respectively.

(R)-PF-04991532 是PF-04991532 的 R 型异构体。PF-04991532 是一种有效的肝选择性葡萄糖激酶激活剂。