nitrofurantoin

Nitrofurantoin (Furadantine) 是一种具有口服活性的广谱内酰胺酶抗菌剂。它是一种抗生素，可研究尿路感染。

Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as calculi and abscess formation, in a rat model ofP. vulgarisurinary tract infection.2Formulations containing nitrofurantoin have been used to treat urinary tract infections. 1.Rocha, H., Da Silva Teles, E., and Barros, M.Site of action of nitrofurantoin in experimental urinary tract infectionAppl. Microbiol.18(4)547-549(1969) 2.Hossack, D.J.N.Proteus vulgaris urinary tract infections in rats; treatment with nitrofuran derivativesBr. J. Pharmacol. Chemother.19(2)306-312(1962)

Nitrofurantoin Sodium is a sodium salt form of nitrofurantoin, a synthetic derivative of imidazolidinedione (hydantoin) that inhibits bacterial DNA, RNA, and cell wall protein synthesis.

Furagin (Furazidine) 是 nitrofurantoin 类似物，有抗菌活性，用于尿路感染。

Cudraxanthone L shows the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.

Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to inhibit growth and metastasis of brea

Gardenolic acid B shows promising hepatoprotective effects on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells. Gardenolic acid B shows significant effects on terminating early pregnancy in rats.

AHD BSA 是呋喃妥因 (AHD) 与牛血清白蛋白 (BSA) 缀合的抗原-佐剂偶联物。该缀合通过偶联抗原和蛋白佐剂来增强疫苗模型中的抗原特异性抗体的产生。缀合物不影响蛋白质折叠或主要表位的完整性，并可促进交叉呈递和抗原特异性 T 细胞的生成。