mgc-12802

Expression system: HEK293 Cells
Length: 21-291, Partial
Activity: SPR

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: Not Tested

CD19 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 58.65 kDa and the accession number is NP_001171569.1.

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-287, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: Not Tested

CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.

CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is XP_005591597.1.

Expression system: HEK293 Cells
Length: 1-287, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: Not Tested

CD19 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.11 kDa and the accession number is NP_001013255.2.