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kt 109

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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
  • KT109
    KT-109,KT 109
    T277521402612-55-8
    KT109 is a selective inhibitor of DAGLβ (IC50 = 42 nM). KT109-treated wild-type mice displayed reductions in LPS-induced allodyni as well as in DAGL-β (- -) micea. Repeated KT109 administration prevented the expression of LPS-induced allodynia, without ev
    • ¥ 9120
    6-8周
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  • (S)-KT109
    (S)-KT109
    T381482055172-61-5
    (S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (S)-KT109 is a less potent inhibitor of DAGLβ (IC50 = 39.81 nM), DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and α β-hydrolase domain-containing protein 6 (ABHD6; IC50 = 630.9 nM) than (R)-KT109 .
    • 待估
    35日内发货
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  • (R)-KT109
    (R)-KT109
    T380312055172-60-4
    (R)-KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (R)-KT109 is an inhibitor of DAGLβ (IC50 = 0.79 nM) and of DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol . It also inhibits α β-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R)-KT109 is more potent at DAGLβ, DAGLα, and ABHD6 than (S)-KT109 .
    • 待估
    35日内发货
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  • KT109 N2 Regioisomer
    T851522749638-90-0
    KT109 N2 regioisomer, an N2-carbamoylated variant of the diacylglycerol lipase β (DAGLβ) inhibitor KT109, serves as an internal standard for KT109 quantification.
    • 待询
    8-10周
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