IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).IGF-I (24-41) (TFA) is amino acids 24 to 41 fragment of Insulin-likeGrowth
NBI-31772 hydrate is a powerful inhibitor of the interaction between insulin-likegrowthfactor (IGF) and IGF-binding proteins (IGFBPs). It acts as a nonpeptide ligand, effectively releasing bioactive IGF-I from the IGF-I IGFBP-3 complex (Ki values for all six human subtypes range from 1-24 nM). This compound demonstrates significant anxiolytic and antidepressant-like effects [1] [2] [3].
IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-likeGrowthFactor I (IGF-I), which contributes to systemic GH activities and exhibits various properties such as anabolic, antioxidant, anti-inflammatory, and cytoprotective.
S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-likegrowthfactor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.