il 3

IL-17A antagonist 3 is an IL-17A antagonist.

IL-17 modulator 3 (US20200247785A1) is a chemical compound that acts as an IL-17 modulator. It has potential applications in researching inflammation, cancer, and autoimmune diseases.

IL-17Amodulator-3 是IL-17A 的调节剂。IL-17Amodulator-3 抑制 IL-17A A，IC50值 ＜10 μM。IL-17Amodulator-3 可以用于炎症、癌症和自身免疫疾病的研究。

IL-17Ainhibitor 3 (Example 602) 作为一种高效的IL-17A抑制剂，主要用于银屑病相关研究。

Anti-MouseIL-3Antibody (MP2-8F8) 是一种源自大鼠的IgG1抗体抑制剂，针对小鼠IL-3。

Anti-MouseIL-15Antibody (AIO.3) 是来源于大鼠的IgG2a, λ 型抗体抑制剂，专用于针对小鼠IL-15。

IL-17-IN-3 (compound 11) 是一种IL-17A的抑制剂，其IC50值为35 nM。在一项针对大鼠的耐受性研究中，以高达300 mg kg 天的剂量连续四天给药后，没有观察到IL-17-IN-3引起任何不良反应。

Anti-MouseIL-17AAntibody (17F3) 是一种小鼠源性的IgG1, κ抗体，专门用于抑制小鼠IL-17A。

Anti-IL-6 Antibody (3Y665) 是一种靶向人 IL-6 的单克隆抗体，是一种 mouse (varialbe region) human (kappa IgG1 constant) chimeric 抗体。

Anti-IL-5 Antibody (3U370) 是一种靶向人 IL-5 的单克隆抗体，是一种 Rabbit IgG 抗体。

Anti-Mouse IL-6 Antibody (MP5-20F3) 是一种大鼠来源的抗小鼠IL-6 的 IgG1, κ 抗体抑制剂。

Anti-Mouse IL-25 Antibody (2C3) 是一种来源于小鼠的IgG1, κ型抗体抑制剂，专门用于对抗小鼠IL-25。

Anti-IL-6R Antibody (3I165) 是一种靶向人 IL-6R 的单克隆抗体，是一种 Mouse IgG1 抗体。

Amlexanox (AA673) 是一种特异性的 IKKε和 TBK1抑制剂，其 IC50=1-2 μM。

Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素， 是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性，可用于研究溃疡性结肠炎。

Hydrocortisone phosphate is the pharmaceutical term for cortisol, which is a steroid hormone, in the glucocorticoid class of hormones, increases blood sugar through gluconeogenesis, to suppress the immune system, and to aid in the metabolism of fat, protein, and carbohydrate.

Difenamizole HCl is the salt form of Difenamizole, a non-steroidal anti-inflammatory drug (NSAID) and analgesic of the pyrazolone group related to metamizole. It has monoaminergic properties, including inhibition of monoamine oxidase, augmentation of pargyline-induced elevation of striatal dopamine levels, inhibition of K+-induced striatal dopamine release, and inhibition of the reuptake of dopamine.

BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.

Tozorakimab (MEDI-3506) 是一种针对 IL-33 的人免疫球蛋白 G1 单克隆抗体，通过 ST2 和 RAGE EGFR 抑制 IL-33 信号传导，减轻炎症和上皮功能障碍，可用于研究慢性阻塞性肺病。

3-Hydroxykynurenamine, also known as 3-Hydroxy-L-kynurenamine or 3-HKA, is a biogenic amine produced via an alternative pathway of tryptophan metabolism. In vitro, 3-HKA has an anti-inflammatory profile by inhibiting the IFN-γ mediated STAT1 NF-κΒ pathway in both mouse and human dendritic cells (DCs) with a consequent decrease in the release of pro-inflammatory chemokines and cytokines, most notably TNF, IL-6, and IL12p70. 3-HKA has protective effects in an experimental mouse model of psoriasis by decreasing skin thickness, erythema, scaling and fissuring, reducing TNF, IL-1β, IFN-γ, and IL-17 production, and inhibiting generation of effector CD8+ T cells. Similarly, in a mouse model of nephrotoxic nephritis, besides reducing inflammatory cytokines, 3-HKA improves proteinuria and serum urea nitrogen, overall ameliorating immune-mediated glomerulonephritis and renal dysfunction.This compound is unstable in powder form and other related salt forms are recommended.

Amygdalin (Laetrile) 是一种植物葡萄糖苷，分离自蔷薇果实的果核中，如杏，桃，杏仁，樱桃和李子。

Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) 是一种核苷二磷酸。它是一种潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用，也可以调节白 IL-6 stat-3 途径。

Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA 受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。

Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。