his pro

His-Pro is a dipeptide comprising histidyl and proline.

Cyclo(his-pro) 是一种口服具有活力的，结构上与促甲状腺激素释放激素相关的环状二肽。它能够抑制NF-κB 核积累，也能够穿越脑血屏障并影响多种炎症和应激反应。

His-Pro hydrochloride is a dipeptide compound comprising histidyl and proline.

PGlu-3-methyl-His-Pro-NH2 TFA enhances binding to pituitary TRH receptors, thereby increasing the stimulation of thyroid-stimulating hormone (TSH) release from the pituitary.

Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2].

pGlu-His-Pro-Gly-NH2（Glp-His-Pro-Gly-NH2）为含四氨基酸肽类化合物，可激发促性腺激素、黄体生成素（LH）与促卵泡激素（FSH）释放。

(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P 是一种选择性的 NK1receptor 拮抗剂。

Protirelin (Thyroliberin) 是高度保守的神经肽，具有促甲状腺激素水平的激素控制作用，及神经调节功能。

Protirelin Acetate(24305-27-9 free base) (Thyroliberin Acetate) 是一种三肽，可刺激促甲状腺素和催乳素的释放。

Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽，序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。

UCF 101 是竞争性的促凋亡蛋白酶Omi HtrA2选择性抑制剂。它对 MI R 损伤具有明显的心脏保护作用，还具有一定的神经保护作用。它在 543 nm 处具有天然的红色荧光，可用于监视其进入哺乳动物细胞的能力。

Angiotensin 1/2 (5-7) is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays a

Angiotensin 1 2 (5-7) acetate 是一种具有 H2N-Ile-His-Pro-OH 序列的肽。血管紧张素是一种寡肽，是一种激素和一种强大的双肽原。它来源于前体分子血管紧张素原，一种在肝脏中产生的血清球蛋白。它在肾素-血管紧张素系统中起重要作用。

Antho-rpamide II is a biologically active neuropeptide isolated from the sea anemone Anthopleura elegantissima.

CH 66 is an inhibitor of renin.

RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome.

R-PEP 27 is an inhibitor of potent renin, decreased plasma angiotensin II, and blood pressure in normal volunteers.

Histidylprolineamide is the N-terminal of TRH.

Thyrotropin-releasing hormone, deamido- is a biochemical.

Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system used3. Other effects of AM include increasing the tolerance of cells to oxidative stress and hypoxic injury and angiogenesis. AM is seen as a positive influence in diseases such as hypertension, myocardial infarction, chronic obstructive pulmonary disease and other cardiovascular diseases, whereas it can be seen as a negative factor in potentiating the potential of cancerous cells to extend their blood supply and cause cell proliferation.

Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. It is also used as therapy for gender identity disorder.

Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性，因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮，是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大，并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。

[Leu144,Arg147]-PLP (139-151)是髓鞘脂蛋白(PLP)的一种突变肽段，包含位于144和147位置的色氨酸到亮氨酸以及组氨酸到精氨酸的替换。使用[Leu144, Arg147]-PLP (139-151)（50 µg）乳化于完全弗氏佐剂(CFA)免疫后，能增加小鼠脾脏中的IL-4水平。它在体外抑制Th1细胞激活，但在体内不抑制，其中它诱导调节性T细胞的产生。用[Leu144, Arg147]-PLP (139-151)预免疫可以延迟由脑炎肽PLP (178-191)、髓磷脂少突细胞蛋白(MOG) (92-106)或髓鞘基础蛋白(MBP)在小鼠中诱导的实验性自身免疫性脑炎(EAE)的发病。

Tiger17是一种环状肽，属于tigerinin-RC1和tigerinin-RC2的衍生物，这两种化合物是在螃蟹吃蛙（F. cancrivora）皮肤分泌物中发现的抗微生物肽。在5至20µg/ml的浓度范围内使用时，Tiger17能增加HaCaT角质形成细胞和人类皮肤成纤维细胞的增殖，并且在20µg/ml的浓度下增加HaCaT细胞的迁移。此外，Tiger17还能增加RAW 264.7巨噬细胞的招募及其TGF-β1和IL-6的分泌。在全层皮肤创伤的小鼠模型中，局部应用20µg/ml的Tiger17能加速伤口闭合和重新上皮化的速度。