gabac

Gaboxadol hydrochloride 是 GABAA 受体激动剂和 GABAC 受体拮抗剂，是非阿片类试剂，可用于缓解疼痛和促进睡眠的研究。它在亚基 α1β2γ2 显示部分激动剂功效，在 α5 亚基显示出一个完整的受体激动剂功效以及在 α4β3δ 亚基也有激动作用。

Gabaculine is an irreversible inhibitor of GABA transaminase (GABA-T; Ki: 2.9 μM). Gabaculine alters plastid development and differentially affects the abundance of plastid-encoded DPOR and nuclear-encoded GluTR.

GABAA agonist

GABAA-ρ antagonist

(R)-3-Amino-4-hydroxybutanoic acid（(R)-3-氨基-4-羟基丁酸）是一种丝氨酸衍生物，是人重组rho1 GABA(C)受体的完全激动剂，同时也是GABA A 和GABA B 受体的调节剂

Muscimol hydrochloride是Muscimol的盐形式。Muscimol是毒蝇伞（Amanita muscaria）的主要精神活性成分，是一种强效和选择性GABAA受体激动剂和部分GABAC受体激动剂，同时对GABAB受体无活性。常用于中枢神经科学研究，具有镇痛、抗焦虑和神经保护作用，具有可以透过血脑屏障和可以口服的优点。

(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.

Guanidinoacetic acid (Standard)（胍基乙酸标准品）在肝脏中发生甲基化反应转化为肌酸并参与能量代谢调控，作为标准品能够用于定量检测，研究肌酸合成通路，遗传性代谢疾病（如胍基乙酸甲基转移酶缺乏症），神经系统疾病，也能作为营养补充剂提高运动表现。Guanidinoacetic acid 是 AMP 活化蛋白激酶（AMPK）的调节剂，能够作为抑制剂下调miR - 133a的表达，是 GABAC 受体的拮抗剂。

Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.