fluoxetine

Fluoxetine (LY-110140) 是一种高度特异性的血清素摄取抑制剂，是选择性 5-羟色胺 (5-HT) 再吸收抑制剂。Fluoxetine 具有抗抑郁活性。

Norfluoxetine Hydrochloride (Norfluoxetine HCl) 是氟西汀的活性代谢物。氟西汀是一种抗抑郁药。

N-Nitroso fluoxetine is a derivative of fluoxetine.1It is genotoxic toS. typhimuriumwhen used at concentrations ranging from 0.06 to 0.12 mg/ml.

meta-Fluoxetine (hydrochloride) 可用于生命科学领域的相关研究。其产品编号为 T37474，CAS号为 79088-29-2。

Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.

Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.

(±)-Fluoxetine-d4 Oxalate 是 (±)-Fluoxetine Oxalate 的氘代化合物。(±)-Fluoxetine Oxalate 的 CAS 号为 114414-02-7。

DB03417 is a compound listed in web page: https: go.drugbank.com drugs DB03417. DB03417 is a potential tryptase inhibitor.

Fluoxetine hydrochloride (Lilly110140) 是一种高度特异性血清素摄取抑制剂。它被用作抗抑郁药，并且通常比传统的抗抑郁药具有更可接受的副作用特征。

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewater effluent.

Norfluoxetine 是抗抑郁药 Fluoxetine 的活性代谢物，也是血清素吸收的选择性抑制剂。

Norfluoxetine-d5 Hydrochloride 是 Norfluoxetine Hydrochloride 的氘代化合物。Norfluoxetine Hydrochloride 的 CAS 号为 57226-68-3。Norfluoxetine Hydrochloride 是氟西汀的活性代谢物。氟西汀是一种抗抑郁药。

(S)-Norfluoxetine，Norfluoxetine 的 S 对映体，属于选择性血清素再摄取抑制剂类化合物。此化合物能提升异孕醇酮的浓度，并有助于减少社交孤立小鼠的攻击行为。

(R)-Norfluoxetine 是 Norfluoxetine 的 (R)-对映体，同时也是一种有效的血清素再摄取抑制剂，Ki 值为 13 nM。它被应用于抑郁症研究。

Seganserin 是一种非选择性5-羟色胺2-HT 受体拮抗剂，可逆转了氟西汀和喹帕嗪对黄体酮诱导的食欲亢进，抑郁和痛觉的抑制作用，逆转氟西汀和喹帕嗪诱导的抗抑郁和镇痛作用。

M40 acetate(143896-17-7 free base) 是一种有效的、非选择性的甘丙肽受体拮抗剂（GAL1 和 GAL2 的 Ki 值分别为 1.82 和 5.1 nM），在体外抑制大鼠脑中甘丙肽 (1-29) 的结合 (IC50 = 3 - 15 nM)。减弱氟西汀的抗抑郁作用并阻止甘丙肽诱导的体内食物摄入。在剂量 > 100 nM 时，对外周 GAL2 受体也表现出较弱的部分激动剂活性。

Seproxetine HCl, a more active enantiomer of N-desmethyl metabolite fluoxetine, works by selectively inhibiting the serotonin uptake carrier.

Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM.